This is an ever-recurring issue (see https://bugs.llvm.org/show_bug.cgi?id=39427 and https://bugs.llvm.org/show_bug.cgi?id=35978) but I believe that thanks to https://reviews.llvm.org/D54472 we can now ship a decent implementation of this.
Basically the fact that llvm::is_trivially_copyable has a consistent behavior across compilers should prevent any ABI issue, and using in-place new instead of memcpy should keep compiler bugs away.