Once we've done our custom isel for these nodes, I think we should be calling removeDeadNode to prune them out of the DAG. Table driven isel ultimately either calls morphNodeTo which modifies a node and doesn't leave dead nodes. Or it emits new nodes and then calls removeDeadNode as part of Opc_CompleteMatch.
If you run a simple multiply test case like this through llc with -debug you'll see a umul_lohi node get printed as part of the dump for Instruction Selection ends.
define i64 @foo(i64 %a, i64 %b) local_unnamed_addr #0 { entry: %conv = zext i64 %a to i128 %conv1 = zext i64 %b to i128 %mul = mul nuw nsw i128 %conv1, %conv %shr = lshr i128 %mul, 64 %conv2 = trunc i128 %shr to i64 ret i64 %conv2 }