The Python code generated by SWIG is compatible with both Python 2 and Python 3. The -py3 option enables Python 2 incompatible features such as function annotations and abstract base classes.
Given that this only affects the generated code (and as such doesn't cause merge conflicts downstream) we're happy to enable it, i.e. this doesn't conflict with our ask in https://lists.llvm.org/pipermail/lldb-dev/2020-August/016388.html.