There are quite a few places in the code base that do something like the following to set the high or low bits in an APInt.
KnownZero |= APInt::getHighBitsSet(BitWidth, BitWidth - 1);
For BitWidths larger than 64 this creates a short lived APInt with malloced storage. I think it might even call malloc twice. Its better to just provide methods that can set the necessary bits without the temporary APInt.
I'll update usages that benefit in a separate patch.