Currently in some places we use signed type to represent size of an access and put explicit casts from unsigned to signed.
For example: int64_t EarlierSize = int64_t(Loc.Size.getValue());
Even though it doesn't loos bits (immidiatly) it may overflow and we end up with negative size. Potentially that cause later code to work incorrectly. A simple expample is a check that size is not negative.
I think it would be safer and clearer if we use unsigned type for the size and handle it appropriately.