diff --git a/llvm/lib/Analysis/InstructionSimplify.cpp b/llvm/lib/Analysis/InstructionSimplify.cpp
--- a/llvm/lib/Analysis/InstructionSimplify.cpp
+++ b/llvm/lib/Analysis/InstructionSimplify.cpp
@@ -4321,10 +4321,14 @@
   // Compute the (pointer) type returned by the GEP instruction.
   Type *LastType = GetElementPtrInst::getIndexedType(SrcTy, Ops.slice(1));
   Type *GEPTy = PointerType::get(LastType, AS);
-  if (VectorType *VT = dyn_cast<VectorType>(Ops[0]->getType()))
-    GEPTy = VectorType::get(GEPTy, VT->getElementCount());
-  else if (VectorType *VT = dyn_cast<VectorType>(Ops[1]->getType()))
-    GEPTy = VectorType::get(GEPTy, VT->getElementCount());
+  for (Value *Op : Ops) {
+    // If one of the operands is a vector, the result type is a vector of
+    // pointers. All vector operands must have the same number of elements.
+    if (VectorType *VT = dyn_cast<VectorType>(Op->getType())) {
+      GEPTy = VectorType::get(GEPTy, VT->getElementCount());
+      break;
+    }
+  }
 
   // getelementptr poison, idx -> poison
   // getelementptr baseptr, poison -> poison
diff --git a/llvm/test/Transforms/InstSimplify/gep.ll b/llvm/test/Transforms/InstSimplify/gep.ll
--- a/llvm/test/Transforms/InstSimplify/gep.ll
+++ b/llvm/test/Transforms/InstSimplify/gep.ll
@@ -315,3 +315,32 @@
   %gep = getelementptr inbounds i32, i32* %c1, i64 %ashr
   ret i32* %gep
 }
+
+define <8 x i32*> @gep_vector_index_op2_poison([144 x i32]* %ptr) {
+; CHECK-LABEL: @gep_vector_index_op2_poison(
+; CHECK-NEXT:    ret <8 x i32*> poison
+;
+  %res = getelementptr inbounds [144 x i32], [144 x i32]* %ptr, i64 0, <8 x i64> poison
+  ret <8 x i32*> %res
+}
+
+%t.1 = type { i32, [144 x i32] }
+
+define <8 x i32*> @gep_vector_index_op3_poison(%t.1* %ptr) {
+; CHECK-LABEL: @gep_vector_index_op3_poison(
+; CHECK-NEXT:    ret <8 x i32*> poison
+;
+  %res = getelementptr inbounds %t.1, %t.1* %ptr, i64 0, i32 1, <8 x i64> poison
+  ret <8 x i32*> %res
+}
+
+%t.2 = type { i32, i32 }
+%t.3 = type { i32, [144 x %t.2 ] }
+
+define <8 x i32*> @gep_vector_index_op3_poison_constant_index_afterwards(%t.3* %ptr) {
+; CHECK-LABEL: @gep_vector_index_op3_poison_constant_index_afterwards(
+; CHECK-NEXT:    ret <8 x i32*> poison
+;
+  %res = getelementptr inbounds %t.3, %t.3* %ptr, i64 0, i32 1, <8 x i64> poison, i32 1
+  ret <8 x i32*> %res
+}