diff --git a/clang/include/clang/AST/OpenMPClause.h b/clang/include/clang/AST/OpenMPClause.h
--- a/clang/include/clang/AST/OpenMPClause.h
+++ b/clang/include/clang/AST/OpenMPClause.h
@@ -7561,14 +7561,49 @@
 };
 
 /// This represents 'destroy' clause in the '#pragma omp depobj'
-/// directive.
+/// directive or the '#pragma omp interop' directive..
 ///
 /// \code
 /// #pragma omp depobj(a) destroy
+/// #pragma omp interop destroy(obj)
 /// \endcode
-/// In this example directive '#pragma omp depobj' has 'destroy' clause.
+/// In these examples directive '#pragma omp depobj' and '#pragma omp interop'
+/// have a 'destroy' clause. The 'interop' directive includes an object.
 class OMPDestroyClause final : public OMPClause {
+  friend class OMPClauseReader;
+
+  /// Location of '('.
+  SourceLocation LParenLoc;
+
+  /// Location of interop variable.
+  SourceLocation VarLoc;
+
+  /// The interop variable.
+  Stmt *InteropVar = nullptr;
+
+  /// Set the interop variable.
+  void setInteropVar(Expr *E) { InteropVar = E; }
+
+  /// Sets the location of '('.
+  void setLParenLoc(SourceLocation Loc) { LParenLoc = Loc; }
+
+  /// Sets the location of the interop variable.
+  void setVarLoc(SourceLocation Loc) { VarLoc = Loc; }
+
 public:
+  /// Build 'destroy' clause with an interop variable expression \a InteropVar.
+  ///
+  /// \param InteropVar The interop variable.
+  /// \param StartLoc Starting location of the clause.
+  /// \param LParenLoc Location of '('.
+  /// \param VarLoc Location of the interop variable.
+  /// \param EndLoc Ending location of the clause.
+  OMPDestroyClause(Expr *InteropVar, SourceLocation StartLoc,
+                   SourceLocation LParenLoc, SourceLocation VarLoc,
+                   SourceLocation EndLoc)
+      : OMPClause(llvm::omp::OMPC_destroy, StartLoc, EndLoc),
+        LParenLoc(LParenLoc), VarLoc(VarLoc), InteropVar(InteropVar) {}
+
   /// Build 'destroy' clause.
   ///
   /// \param StartLoc Starting location of the clause.
@@ -7581,11 +7616,24 @@
       : OMPClause(llvm::omp::OMPC_destroy, SourceLocation(), SourceLocation()) {
   }
 
+  /// Returns the location of '('.
+  SourceLocation getLParenLoc() const { return LParenLoc; }
+
+  /// Returns the location of the interop variable.
+  SourceLocation getVarLoc() const { return VarLoc; }
+
+  /// Returns the interop variable.
+  Expr *getInteropVar() const { return cast_or_null<Expr>(InteropVar); }
+
   child_range children() {
+    if (InteropVar)
+      return child_range(&InteropVar, &InteropVar + 1);
     return child_range(child_iterator(), child_iterator());
   }
 
   const_child_range children() const {
+    if (InteropVar)
+      return const_child_range(&InteropVar, &InteropVar + 1);
     return const_child_range(const_child_iterator(), const_child_iterator());
   }
 
diff --git a/clang/include/clang/AST/RecursiveASTVisitor.h b/clang/include/clang/AST/RecursiveASTVisitor.h
--- a/clang/include/clang/AST/RecursiveASTVisitor.h
+++ b/clang/include/clang/AST/RecursiveASTVisitor.h
@@ -3210,7 +3210,8 @@
 }
 
 template <typename Derived>
-bool RecursiveASTVisitor<Derived>::VisitOMPDestroyClause(OMPDestroyClause *) {
+bool RecursiveASTVisitor<Derived>::VisitOMPDestroyClause(OMPDestroyClause *C) {
+  TRY_TO(TraverseStmt(C->getInteropVar()));
   return true;
 }
 
diff --git a/clang/include/clang/Sema/Sema.h b/clang/include/clang/Sema/Sema.h
--- a/clang/include/clang/Sema/Sema.h
+++ b/clang/include/clang/Sema/Sema.h
@@ -10998,8 +10998,11 @@
                                   SourceLocation VarLoc, SourceLocation EndLoc);
 
   /// Called on well-formed 'destroy' clause.
-  OMPClause *ActOnOpenMPDestroyClause(SourceLocation StartLoc,
+  OMPClause *ActOnOpenMPDestroyClause(Expr *InteropVar, SourceLocation StartLoc,
+                                      SourceLocation LParenLoc,
+                                      SourceLocation VarLoc,
                                       SourceLocation EndLoc);
+
   /// Called on well-formed 'threads' clause.
   OMPClause *ActOnOpenMPThreadsClause(SourceLocation StartLoc,
                                       SourceLocation EndLoc);
diff --git a/clang/lib/AST/OpenMPClause.cpp b/clang/lib/AST/OpenMPClause.cpp
--- a/clang/lib/AST/OpenMPClause.cpp
+++ b/clang/lib/AST/OpenMPClause.cpp
@@ -1807,8 +1807,13 @@
   OS << ")";
 }
 
-void OMPClausePrinter::VisitOMPDestroyClause(OMPDestroyClause *) {
+void OMPClausePrinter::VisitOMPDestroyClause(OMPDestroyClause *Node) {
   OS << "destroy";
+  if (Expr *E = Node->getInteropVar()) {
+    OS << "(";
+    E->printPretty(OS, nullptr, Policy);
+    OS << ")";
+  }
 }
 
 template<typename T>
diff --git a/clang/lib/AST/StmtProfile.cpp b/clang/lib/AST/StmtProfile.cpp
--- a/clang/lib/AST/StmtProfile.cpp
+++ b/clang/lib/AST/StmtProfile.cpp
@@ -552,7 +552,10 @@
     Profiler->VisitStmt(C->getInteropVar());
 }
 
-void OMPClauseProfiler::VisitOMPDestroyClause(const OMPDestroyClause *) {}
+void OMPClauseProfiler::VisitOMPDestroyClause(const OMPDestroyClause *C) {
+  if (C->getInteropVar())
+    Profiler->VisitStmt(C->getInteropVar());
+}
 
 template<typename T>
 void OMPClauseProfiler::VisitOMPClauseList(T *Node) {
diff --git a/clang/lib/Parse/ParseOpenMP.cpp b/clang/lib/Parse/ParseOpenMP.cpp
--- a/clang/lib/Parse/ParseOpenMP.cpp
+++ b/clang/lib/Parse/ParseOpenMP.cpp
@@ -2865,7 +2865,6 @@
   case OMPC_unified_shared_memory:
   case OMPC_reverse_offload:
   case OMPC_dynamic_allocators:
-  case OMPC_destroy:
     // OpenMP [2.7.1, Restrictions, p. 9]
     //  Only one ordered clause can appear on a loop directive.
     // OpenMP [2.7.1, Restrictions, C/C++, p. 4]
@@ -2929,6 +2928,17 @@
   case OMPC_uses_allocators:
     Clause = ParseOpenMPUsesAllocatorClause(DKind);
     break;
+  case OMPC_destroy:
+    if (DKind != OMPD_interop) {
+      if (!FirstClause) {
+        Diag(Tok, diag::err_omp_more_one_clause)
+            << getOpenMPDirectiveName(DKind) << getOpenMPClauseName(CKind) << 0;
+        ErrorFound = true;
+      }
+      Clause = ParseOpenMPClause(CKind, WrongDirective);
+      break;
+    }
+    LLVM_FALLTHROUGH;
   case OMPC_init:
   case OMPC_use:
     Clause = ParseOpenMPInteropClause(CKind, WrongDirective);
@@ -3160,6 +3170,10 @@
     return Actions.ActOnOpenMPUseClause(InteropVarExpr.get(), Loc,
                                         T.getOpenLocation(), VarLoc, RLoc);
 
+  if (Kind == OMPC_destroy)
+    return Actions.ActOnOpenMPDestroyClause(InteropVarExpr.get(), Loc,
+                                            T.getOpenLocation(), VarLoc, RLoc);
+
   llvm_unreachable("Unexpected interop variable clause.");
 }
 
diff --git a/clang/lib/Sema/SemaOpenMP.cpp b/clang/lib/Sema/SemaOpenMP.cpp
--- a/clang/lib/Sema/SemaOpenMP.cpp
+++ b/clang/lib/Sema/SemaOpenMP.cpp
@@ -14441,7 +14441,9 @@
     Res = ActOnOpenMPDynamicAllocatorsClause(StartLoc, EndLoc);
     break;
   case OMPC_destroy:
-    Res = ActOnOpenMPDestroyClause(StartLoc, EndLoc);
+    Res = ActOnOpenMPDestroyClause(/*InteropVar=*/nullptr, StartLoc,
+                                   /*LParenLoc=*/SourceLocation(),
+                                   /*VarLoc=*/SourceLocation(), EndLoc);
     break;
   case OMPC_if:
   case OMPC_final:
@@ -14599,19 +14601,13 @@
   return new (Context) OMPDynamicAllocatorsClause(StartLoc, EndLoc);
 }
 
-OMPClause *Sema::ActOnOpenMPDestroyClause(SourceLocation StartLoc,
-                                          SourceLocation EndLoc) {
-  return new (Context) OMPDestroyClause(StartLoc, EndLoc);
-}
-
 StmtResult Sema::ActOnOpenMPInteropDirective(ArrayRef<OMPClause *> Clauses,
                                              SourceLocation StartLoc,
                                              SourceLocation EndLoc) {
 
   // OpenMP 5.1 [2.15.1, interop Construct, Restrictions]
   // At least one action-clause must appear on a directive.
-  // TODO: also add 'destroy' here.
-  if (!hasClauses(Clauses, OMPC_init, OMPC_use, OMPC_nowait)) {
+  if (!hasClauses(Clauses, OMPC_init, OMPC_use, OMPC_destroy, OMPC_nowait)) {
     StringRef Expected = "'init', 'use', 'destroy', or 'nowait'";
     Diag(StartLoc, diag::err_omp_no_clause_for_directive)
         << Expected << getOpenMPDirectiveName(OMPD_interop);
@@ -14662,8 +14658,11 @@
       const auto *UC = cast<OMPUseClause>(C);
       VarLoc = UC->getVarLoc();
       DRE = dyn_cast_or_null<DeclRefExpr>(UC->getInteropVar());
+    } else if (ClauseKind == OMPC_destroy) {
+      const auto *DC = cast<OMPDestroyClause>(C);
+      VarLoc = DC->getVarLoc();
+      DRE = dyn_cast_or_null<DeclRefExpr>(DC->getInteropVar());
     }
-    // TODO: 'destroy' clause to be added here.
 
     if (!DRE)
       continue;
@@ -14723,8 +14722,7 @@
 
   // OpenMP 5.1 [2.15.1, interop Construct, Restrictions]
   // The interop-var passed to init or destroy must be non-const.
-  // TODO: 'destroy' clause too.
-  if (Kind == OMPC_init &&
+  if ((Kind == OMPC_init || Kind == OMPC_destroy) &&
       isConstNotMutableType(SemaRef, InteropVarExpr->getType())) {
     SemaRef.Diag(VarLoc, diag::err_omp_interop_variable_expected)
         << /*non-const*/ 1;
@@ -14773,6 +14771,19 @@
       OMPUseClause(InteropVar, StartLoc, LParenLoc, VarLoc, EndLoc);
 }
 
+OMPClause *Sema::ActOnOpenMPDestroyClause(Expr *InteropVar,
+                                          SourceLocation StartLoc,
+                                          SourceLocation LParenLoc,
+                                          SourceLocation VarLoc,
+                                          SourceLocation EndLoc) {
+  if (InteropVar &&
+      !isValidInteropVariable(*this, InteropVar, VarLoc, OMPC_destroy))
+    return nullptr;
+
+  return new (Context)
+      OMPDestroyClause(InteropVar, StartLoc, LParenLoc, VarLoc, EndLoc);
+}
+
 OMPClause *Sema::ActOnOpenMPVarListClause(
     OpenMPClauseKind Kind, ArrayRef<Expr *> VarList, Expr *DepModOrTailExpr,
     const OMPVarListLocTy &Locs, SourceLocation ColonLoc,
diff --git a/clang/lib/Sema/TreeTransform.h b/clang/lib/Sema/TreeTransform.h
--- a/clang/lib/Sema/TreeTransform.h
+++ b/clang/lib/Sema/TreeTransform.h
@@ -2196,6 +2196,18 @@
                                           VarLoc, EndLoc);
   }
 
+  /// Build a new OpenMP 'destroy' clause.
+  ///
+  /// By default, performs semantic analysis to build the new OpenMP clause.
+  /// Subclasses may override this routine to provide different behavior.
+  OMPClause *RebuildOMPDestroyClause(Expr *InteropVar, SourceLocation StartLoc,
+                                     SourceLocation LParenLoc,
+                                     SourceLocation VarLoc,
+                                     SourceLocation EndLoc) {
+    return getSema().ActOnOpenMPDestroyClause(InteropVar, StartLoc, LParenLoc,
+                                              VarLoc, EndLoc);
+  }
+
   /// Rebuild the operand to an Objective-C \@synchronized statement.
   ///
   /// By default, performs semantic analysis to build the new statement.
@@ -9343,8 +9355,15 @@
 template <typename Derived>
 OMPClause *
 TreeTransform<Derived>::TransformOMPDestroyClause(OMPDestroyClause *C) {
-  // No need to rebuild this clause, no template-dependent parameters.
-  return C;
+  ExprResult ER;
+  if (Expr *IV = C->getInteropVar()) {
+    ER = getDerived().TransformExpr(IV);
+    if (ER.isInvalid())
+      return nullptr;
+  }
+  return getDerived().RebuildOMPDestroyClause(ER.get(), C->getBeginLoc(),
+                                              C->getLParenLoc(), C->getVarLoc(),
+                                              C->getEndLoc());
 }
 
 template <typename Derived>
diff --git a/clang/lib/Serialization/ASTReader.cpp b/clang/lib/Serialization/ASTReader.cpp
--- a/clang/lib/Serialization/ASTReader.cpp
+++ b/clang/lib/Serialization/ASTReader.cpp
@@ -12156,7 +12156,11 @@
   C->setVarLoc(Record.readSourceLocation());
 }
 
-void OMPClauseReader::VisitOMPDestroyClause(OMPDestroyClause *) {}
+void OMPClauseReader::VisitOMPDestroyClause(OMPDestroyClause *C) {
+  C->setInteropVar(Record.readSubExpr());
+  C->setLParenLoc(Record.readSourceLocation());
+  C->setVarLoc(Record.readSourceLocation());
+}
 
 void OMPClauseReader::VisitOMPUnifiedAddressClause(OMPUnifiedAddressClause *) {}
 
diff --git a/clang/lib/Serialization/ASTWriter.cpp b/clang/lib/Serialization/ASTWriter.cpp
--- a/clang/lib/Serialization/ASTWriter.cpp
+++ b/clang/lib/Serialization/ASTWriter.cpp
@@ -6231,7 +6231,11 @@
   Record.AddSourceLocation(C->getVarLoc());
 }
 
-void OMPClauseWriter::VisitOMPDestroyClause(OMPDestroyClause *) {}
+void OMPClauseWriter::VisitOMPDestroyClause(OMPDestroyClause *C) {
+  Record.AddStmt(C->getInteropVar());
+  Record.AddSourceLocation(C->getLParenLoc());
+  Record.AddSourceLocation(C->getVarLoc());
+}
 
 void OMPClauseWriter::VisitOMPPrivateClause(OMPPrivateClause *C) {
   Record.push_back(C->varlist_size());
diff --git a/clang/test/OpenMP/interop_ast_print.cpp b/clang/test/OpenMP/interop_ast_print.cpp
--- a/clang/test/OpenMP/interop_ast_print.cpp
+++ b/clang/test/OpenMP/interop_ast_print.cpp
@@ -41,6 +41,12 @@
   //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
   #pragma omp interop use(I)
 
+  //PRINT: #pragma omp interop destroy(I)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
+  #pragma omp interop destroy(I)
+
   //PRINT: #pragma omp interop init(target : IRef)
   //DUMP: OMPInteropDirective
   //DUMP: OMPInitClause
@@ -53,6 +59,12 @@
   //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'IRef'
   #pragma omp interop use(IRef)
 
+  //PRINT: #pragma omp interop destroy(IRef)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'IRef'
+  #pragma omp interop destroy(IRef)
+
   const omp_interop_t CI = (omp_interop_t)0;
   //PRINT: #pragma omp interop use(CI)
   //DUMP: OMPInteropDirective
@@ -80,6 +92,16 @@
   //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
   #pragma omp interop device(dev) depend(inout:ap) use(I)
 
+  //PRINT: #pragma omp interop device(dev) depend(inout : ap) destroy(I)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDeviceClause
+  //DUMP: DeclRefExpr{{.*}}'dev' 'int'
+  //DUMP: OMPDependClause
+  //DUMP: DeclRefExpr{{.*}}'ap' 'int *'
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
+  #pragma omp interop device(dev) depend(inout:ap) destroy(I)
+
   //PRINT: #pragma omp interop init(prefer_type(1,2,3,4,5,6), targetsync : I)
   //DUMP: OMPInteropDirective
   //DUMP: OMPInitClause
@@ -150,6 +172,30 @@
   //DUMP: OMPUseClause
   //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'J'
   #pragma omp interop use(I) use(J)
+
+  //PRINT: #pragma omp interop destroy(I) destroy(J)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'J'
+  #pragma omp interop destroy(I) destroy(J)
+
+  //PRINT: #pragma omp interop init(target : I) destroy(J)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPInitClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'J'
+  #pragma omp interop init(target:I) destroy(J)
+
+  //PRINT: #pragma omp interop destroy(I) use(J)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'I'
+  //DUMP: OMPUseClause
+  //DUMP: DeclRefExpr{{.*}}'omp_interop_t'{{.*}}Var{{.*}}'J'
+  #pragma omp interop destroy(I) use(J)
 }
 
 //DUMP: FunctionTemplateDecl{{.*}}fooTemp
@@ -200,6 +246,12 @@
   //DUMP: DeclRefExpr{{.*}}ParmVar{{.*}}'t' 'T'
   #pragma omp interop use(t)
 
+  //PRINT: #pragma omp interop destroy(t)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}ParmVar{{.*}}'t' 'T'
+  #pragma omp interop destroy(t)
+
   //DUMP: FunctionDecl{{.*}}barTemp 'void (void *)'
   //DUMP: TemplateArgument type 'void *'
   //DUMP: ParmVarDecl{{.*}}t 'void *'
@@ -211,6 +263,10 @@
   //DUMP: OMPUseClause
   //DUMP: DeclRefExpr{{.*}}ParmVar{{.*}}'t' 'void *'
   //PRINT: #pragma omp interop use(t)
+  //DUMP: OMPInteropDirective
+  //DUMP: OMPDestroyClause
+  //DUMP: DeclRefExpr{{.*}}ParmVar{{.*}}'t' 'void *'
+  //PRINT: #pragma omp interop destroy(t)
 }
 
 void bar()
diff --git a/clang/test/OpenMP/interop_messages.cpp b/clang/test/OpenMP/interop_messages.cpp
--- a/clang/test/OpenMP/interop_messages.cpp
+++ b/clang/test/OpenMP/interop_messages.cpp
@@ -17,6 +17,9 @@
   //expected-error@+1 {{use of undeclared identifier 'NoDeclVar'}}
   #pragma omp interop use(NoDeclVar) use(Another)
 
+  //expected-error@+1 {{use of undeclared identifier 'NoDeclVar'}}
+  #pragma omp interop destroy(NoDeclVar) destroy(Another)
+
   //expected-error@+2 {{expected interop type: 'target' and/or 'targetsync'}}
   //expected-error@+1 {{expected expression}}
   #pragma omp interop init(InteropVar) init(target:Another)
@@ -38,6 +41,9 @@
   //expected-error@+1 {{interop variable must be of type 'omp_interop_t'}}
   #pragma omp interop use(IntVar) use(Another)
 
+  //expected-error@+1 {{interop variable must be of type 'omp_interop_t'}}
+  #pragma omp interop destroy(IntVar) destroy(Another)
+
   //expected-error@+1 {{interop variable must be of type 'omp_interop_t'}}
   #pragma omp interop init(prefer_type(1,"sycl",3),target:SVar) \
                       init(target:Another)
@@ -45,6 +51,9 @@
   //expected-error@+1 {{interop variable must be of type 'omp_interop_t'}}
   #pragma omp interop use(SVar) use(Another)
 
+  //expected-error@+1 {{interop variable must be of type 'omp_interop_t'}}
+  #pragma omp interop destroy(SVar) destroy(Another)
+
   int a, b;
   //expected-error@+1 {{expected variable of type 'omp_interop_t'}}
   #pragma omp interop init(target:a+b) init(target:Another)
@@ -52,10 +61,16 @@
   //expected-error@+1 {{expected variable of type 'omp_interop_t'}}
   #pragma omp interop use(a+b) use(Another)
 
+  //expected-error@+1 {{expected variable of type 'omp_interop_t'}}
+  #pragma omp interop destroy(a+b) destroy(Another)
+
   const omp_interop_t C = (omp_interop_t)5;
   //expected-error@+1 {{expected non-const variable of type 'omp_interop_t'}}
   #pragma omp interop init(target:C) init(target:Another)
 
+  //expected-error@+1 {{expected non-const variable of type 'omp_interop_t'}}
+  #pragma omp interop destroy(C) destroy(Another)
+
   //expected-error@+1 {{prefer_list item must be a string literal or constant integral expression}}
   #pragma omp interop init(prefer_type(1.0),target:InteropVar) \
                       init(target:Another)
@@ -79,9 +94,18 @@
   //expected-error@+1 {{interop variable 'InteropVar' used in multiple action clauses}}
   #pragma omp interop use(InteropVar) use(InteropVar)
 
+  //expected-error@+1 {{interop variable 'InteropVar' used in multiple action clauses}}
+  #pragma omp interop destroy(InteropVar) destroy(InteropVar)
+
   //expected-error@+1 {{interop variable 'InteropVar' used in multiple action clauses}}
   #pragma omp interop init(target:InteropVar) use(InteropVar)
 
+  //expected-error@+1 {{interop variable 'InteropVar' used in multiple action clauses}}
+  #pragma omp interop init(target:InteropVar) destroy(InteropVar)
+
+  //expected-error@+1 {{interop variable 'InteropVar' used in multiple action clauses}}
+  #pragma omp interop use(InteropVar) destroy(InteropVar)
+
   //expected-error@+1 {{directive '#pragma omp interop' cannot contain more than one 'device' clause}}
   #pragma omp interop init(target:InteropVar) device(0) device(1)
 
@@ -99,5 +123,7 @@
   #pragma omp interop init(prefer_type(1,"sycl",3),target:InteropVar) nowait
   //expected-error@+1 {{'omp_interop_t' type not found; include <omp.h>}}
   #pragma omp interop use(InteropVar) nowait
+  //expected-error@+1 {{'omp_interop_t' type not found; include <omp.h>}}
+  #pragma omp interop destroy(InteropVar) nowait
 }
 #endif
diff --git a/clang/tools/libclang/CIndex.cpp b/clang/tools/libclang/CIndex.cpp
--- a/clang/tools/libclang/CIndex.cpp
+++ b/clang/tools/libclang/CIndex.cpp
@@ -2286,7 +2286,10 @@
   Visitor->AddStmt(C->getInteropVar());
 }
 
-void OMPClauseEnqueue::VisitOMPDestroyClause(const OMPDestroyClause *) {}
+void OMPClauseEnqueue::VisitOMPDestroyClause(const OMPDestroyClause *C) {
+  if (C->getInteropVar())
+    Visitor->AddStmt(C->getInteropVar());
+}
 
 void OMPClauseEnqueue::VisitOMPUnifiedAddressClause(
     const OMPUnifiedAddressClause *) {}
diff --git a/llvm/include/llvm/Frontend/OpenMP/OMP.td b/llvm/include/llvm/Frontend/OpenMP/OMP.td
--- a/llvm/include/llvm/Frontend/OpenMP/OMP.td
+++ b/llvm/include/llvm/Frontend/OpenMP/OMP.td
@@ -1650,6 +1650,7 @@
   let allowedClauses = [
     VersionedClause<OMPC_Device>,
     VersionedClause<OMPC_Depend>,
+    VersionedClause<OMPC_Destroy>,
     VersionedClause<OMPC_Init>,
     VersionedClause<OMPC_NoWait>,
     VersionedClause<OMPC_Use>,