diff --git a/openmp/CMakeLists.txt b/openmp/CMakeLists.txt
--- a/openmp/CMakeLists.txt
+++ b/openmp/CMakeLists.txt
@@ -55,11 +55,6 @@
 set(OPENMP_TEST_OPENMP_FLAGS ${OPENMP_TEST_COMPILER_OPENMP_FLAGS} CACHE STRING
   "OpenMP compiler flag to use for testing OpenMP runtime libraries.")
 
-
-# Build host runtime library.
-add_subdirectory(runtime)
-
-
 set(ENABLE_LIBOMPTARGET ON)
 # Currently libomptarget cannot be compiled on Windows or MacOS X.
 # Since the device plugins are only supported on Linux anyway,
@@ -86,6 +81,11 @@
        ${ENABLE_LIBOMPTARGET})
 option(OPENMP_ENABLE_LIBOMPTARGET_PROFILING "Enable time profiling for libomptarget."
        ${ENABLE_LIBOMPTARGET})
+
+# Build host runtime library, after LIBOMPTARGET variables are set since they are needed
+# to enable time profiling support in the OpenMP runtime.
+add_subdirectory(runtime)
+
 if (OPENMP_ENABLE_LIBOMPTARGET)
   # Check that the library can actually be built.
   if (APPLE OR WIN32)
diff --git a/openmp/runtime/src/CMakeLists.txt b/openmp/runtime/src/CMakeLists.txt
--- a/openmp/runtime/src/CMakeLists.txt
+++ b/openmp/runtime/src/CMakeLists.txt
@@ -50,6 +50,15 @@
   include_directories(${LIBOMP_HWLOC_INSTALL_DIR}/include)
 endif()
 
+# Building with time profiling support for libomptarget requires
+# LLVM directory includes.
+if(LIBOMPTARGET_PROFILING_SUPPORT)
+  include_directories(
+    ${LLVM_MAIN_INCLUDE_DIR}
+    ${LLVM_INCLUDE_DIR}
+  )
+endif()
+
 # Getting correct source files to build library
 set(LIBOMP_CXXFILES)
 set(LIBOMP_ASMFILES)