diff --git a/openmp/README.rst b/openmp/README.rst
--- a/openmp/README.rst
+++ b/openmp/README.rst
@@ -248,8 +248,8 @@
   out-of-tree builds.
 
 **LIBOMPTARGET_OPENMP_HOST_RTL_FOLDER** = ``""``
-  Path of the folder that contains ``libomp.so``.  This is required for testing
-  out-of-tree builds.
+  Path of the folder that contains ``libomp.so``, and ``libLLVMSupport.so``
+  when profiling is enabled.  This is required for testing.
 
 Options for ``NVPTX device RTL``
 --------------------------------
diff --git a/openmp/libomptarget/CMakeLists.txt b/openmp/libomptarget/CMakeLists.txt
--- a/openmp/libomptarget/CMakeLists.txt
+++ b/openmp/libomptarget/CMakeLists.txt
@@ -68,14 +68,10 @@
 add_subdirectory(${LIBOMPTARGET_SRC_DIR})
 
 # Definitions for testing, for reuse when testing libomptarget-nvptx.
-if(OPENMP_STANDALONE_BUILD)
-  set(LIBOMPTARGET_OPENMP_HEADER_FOLDER "${CMAKE_CURRENT_BINARY_DIR}/../runtime/src" CACHE STRING
-    "Path to folder containing omp.h")
-  set(LIBOMPTARGET_OPENMP_HOST_RTL_FOLDER "${CMAKE_CURRENT_BINARY_DIR}/../runtime/src" CACHE STRING
-    "Path to folder containing libomp.so")
-else()
-  set(LIBOMPTARGET_OPENMP_HEADER_FOLDER "${CMAKE_CURRENT_BINARY_DIR}/../runtime/src")
-endif()
+set(LIBOMPTARGET_OPENMP_HEADER_FOLDER "${LIBOMP_INCLUDE_DIR}" CACHE STRING
+  "Path to folder containing omp.h")
+set(LIBOMPTARGET_OPENMP_HOST_RTL_FOLDER "${LIBOMP_LIBRARY_DIR}" CACHE STRING
+  "Path to folder containing libomp.so, and libLLVMSupport.so with profiling enabled")
 
 
 # Build offloading plugins and device RTLs if they are available.