Index: .gitignore
===================================================================
--- .gitignore
+++ .gitignore
@@ -63,3 +63,5 @@
 /clang/utils/analyzer/projects/*/PatchedSource
 /clang/utils/analyzer/projects/*/ScanBuildResults
 /clang/utils/analyzer/projects/*/RefScanBuildResults
+# automodapi generates temporary files here.
+/lldb/docs/python_api/api/
Index: lldb/docs/CMakeLists.txt
===================================================================
--- lldb/docs/CMakeLists.txt
+++ lldb/docs/CMakeLists.txt
@@ -15,60 +15,43 @@
   )
 endif()
 
-if (LLDB_ENABLE_PYTHON)
-  find_program(EPYDOC_EXECUTABLE NAMES epydoc epydoc.py)
-  if(EPYDOC_EXECUTABLE)
-    message(STATUS "Found epydoc - ${EPYDOC_EXECUTABLE}")
-
-    find_program(DOT_EXECUTABLE dot)
-    if(DOT_EXECUTABLE)
-      set(EPYDOC_OPTIONS ${EPYDOC_OPTIONS} --graph all --dotpath ${DOT_EXECUTABLE})
-      message(STATUS "Found dot - ${DOT_EXECUTABLE}")
-    endif()
-
-    # Pretend to make a python package so that we can generate the reference.
-    # Because we don't build liblldb, epydoc will complain that the import of
-    # _lldb.so failed, but that doesn't prevent it from generating the docs.
-    file(MAKE_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}/lldb)
-    get_target_property(lldb_bindings_dir swig_wrapper_python BINARY_DIR)
-    add_custom_target(lldb-python-doc-package
-      COMMAND "${CMAKE_COMMAND}" -E copy "${lldb_bindings_dir}/lldb.py" "${CMAKE_CURRENT_BINARY_DIR}/lldb/__init__.py"
-      COMMENT "Copying lldb.py to pretend package.")
-    add_dependencies(lldb-python-doc-package swig_wrapper_python)
+if (LLVM_ENABLE_SPHINX)
+  include(AddSphinxTarget)
+endif()
 
-    set(DOC_DIR "${CMAKE_CURRENT_SOURCE_DIR}/doc")
-    file(MAKE_DIRECTORY "${DOC_DIR}")
-    add_custom_target(lldb-python-doc
-      ${EPYDOC_EXECUTABLE}
-      --html
-      lldb
-      -o ${CMAKE_CURRENT_BINARY_DIR}/python_reference
-      --name "LLDB python API"
-      --url "http://lldb.llvm.org"
-      ${EPYDOC_OPTIONS}
-      WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}
-      COMMENT "Generating LLDB Python API reference with epydoc" VERBATIM
-    )
-    add_dependencies(lldb-python-doc swig_wrapper_python lldb-python-doc-package)
-  else()
-    message(STATUS "Could NOT find epydoc")
-  endif()
+if (LLDB_ENABLE_PYTHON AND SPHINX_FOUND)
+  # Pretend that the SWIG generated API is a Python package.
+  file(MAKE_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}/lldb)
+  get_target_property(lldb_bindings_dir swig_wrapper_python BINARY_DIR)
+  add_custom_target(lldb-python-doc-package
+    COMMAND "${CMAKE_COMMAND}" -E copy "${lldb_bindings_dir}/lldb.py" "${CMAKE_CURRENT_BINARY_DIR}/lldb/__init__.py"
+    COMMENT "Copying lldb.py to pretend its a Python package.")
+  add_dependencies(lldb-python-doc-package swig_wrapper_python)
+
+  # Let sphinx generate the Python API reference.
+  # The sphinx config needs to know where the generated LLDB module is.
+  # There doesn't seem a way to pass pass parameters to the conf.py script,
+  # so pass the path to the module via the LLDB_SWIG_MODULE environment variable.
+  add_custom_target(lldb-python-doc
+    ${CMAKE_COMMAND} -E env "LLDB_SWIG_MODULE=${CMAKE_CURRENT_BINARY_DIR}"
+    ${SPHINX_EXECUTABLE} -M html "${CMAKE_CURRENT_SOURCE_DIR}/python_api" "${CMAKE_CURRENT_BINARY_DIR}/python_reference/"
+    WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}
+    COMMENT "Generating LLDB Python API reference" VERBATIM
+  )
+  add_dependencies(lldb-python-doc swig_wrapper_python lldb-python-doc-package)
 endif ()
 
-if (LLVM_ENABLE_SPHINX)
-  include(AddSphinxTarget)
-  if (SPHINX_FOUND)
-    if (${SPHINX_OUTPUT_HTML})
-      add_sphinx_target(html lldb)
-      # Sphinx does not reliably update the custom CSS files, so force
-      # a clean rebuild of the documentation every time.
-      add_custom_target(clean-lldb-html COMMAND "${CMAKE_COMMAND}" -E
-        remove_directory ${CMAKE_CURRENT_BINARY_DIR}/html)
-      add_dependencies(docs-lldb-html clean-lldb-html)
-    endif()
+if (SPHINX_FOUND)
+  if (${SPHINX_OUTPUT_HTML})
+    add_sphinx_target(html lldb)
+    # Sphinx does not reliably update the custom CSS files, so force
+    # a clean rebuild of the documentation every time.
+    add_custom_target(clean-lldb-html COMMAND "${CMAKE_COMMAND}" -E
+      remove_directory ${CMAKE_CURRENT_BINARY_DIR}/html)
+    add_dependencies(docs-lldb-html clean-lldb-html)
+  endif()
 
-    if (${SPHINX_OUTPUT_MAN})
-      add_sphinx_target(man lldb)
-    endif()
+  if (${SPHINX_OUTPUT_MAN})
+    add_sphinx_target(man lldb)
   endif()
 endif()
Index: lldb/docs/_lldb/__init__.py
===================================================================
--- /dev/null
+++ lldb/docs/_lldb/__init__.py
@@ -0,0 +1,9 @@
+from unittest.mock import Mock
+import sys
+import types
+
+# This package acts as a mock implementation of the native _lldb module so
+# that generating the LLDB documentation doesn't actually require building all
+# of LLDB.
+module_name = '_lldb'
+sys.modules[module_name] = Mock()
Index: lldb/docs/python_api/conf.py
===================================================================
--- /dev/null
+++ lldb/docs/python_api/conf.py
@@ -0,0 +1,19 @@
+# Minimal sphinx configuration for generating LLDB's Python API reference.
+
+import os
+import sys
+# Add the parent directory that contains the mock _lldb native module which
+# is imported by the `lldb` module.
+sys.path.insert(0, os.path.abspath(".."))
+# Add the build directory that contains the `lldb` module. LLDB_SWIG_MODULE is
+# set by CMake.
+sys.path.insert(0, os.getenv("LLDB_SWIG_MODULE"))
+
+project = 'LLDB Python API'
+copyright = '2021, The LLDB Team'
+author = 'The LLDB Team'
+
+extensions = ['sphinx_automodapi.automodapi']
+
+exclude_patterns = []
+html_theme = 'sphinxdoc'
Index: lldb/docs/python_api/index.rst
===================================================================
--- /dev/null
+++ lldb/docs/python_api/index.rst
@@ -0,0 +1,102 @@
+LLDB Python API
+================================
+
+..
+  The long list of "skip" filters out several global functions that are
+  generated by SWIG (but which are not useful as they are only the
+  backend for their respective static functions in the classes).
+  Without this list
+.. automodapi:: lldb
+  :no-inheritance-diagram:
+  :skip: SBBreakpoint_EventIsBreakpointEvent
+  :skip: SBBreakpoint_GetBreakpointEventTypeFromEvent
+  :skip: SBBreakpoint_GetBreakpointFromEvent
+  :skip: SBBreakpoint_GetBreakpointLocationAtIndexFromEvent
+  :skip: SBBreakpoint_GetNumBreakpointLocationsFromEvent
+  :skip: SBCommandInterpreter_EventIsCommandInterpreterEvent
+  :skip: SBCommandInterpreter_GetArgumentDescriptionAsCString
+  :skip: SBCommandInterpreter_GetArgumentTypeAsCString
+  :skip: SBCommandInterpreter_GetBroadcasterClass
+  :skip: SBCommunication_GetBroadcasterClass
+  :skip: SBData_CreateDataFromCString
+  :skip: SBData_CreateDataFromDoubleArray
+  :skip: SBData_CreateDataFromSInt
+  :skip: SBData_CreateDataFromSInt
+  :skip: SBData_CreateDataFromUInt
+  :skip: SBData_CreateDataFromUInt
+  :skip: SBData_CreateDataFromSInt32Array
+  :skip: SBData_CreateDataFromSInt64Array
+  :skip: SBData_CreateDataFromUInt32Array
+  :skip: SBData_CreateDataFromUInt64Array
+  :skip: SBDebugger_Create
+  :skip: SBDebugger_Create
+  :skip: SBDebugger_Destroy
+  :skip: SBDebugger_FindDebuggerWithID
+  :skip: SBDebugger_GetBuildConfiguration
+  :skip: SBDebugger_GetDefaultArchitecture
+  :skip: SBDebugger_GetInternalVariableValue
+  :skip: SBDebugger_GetVersionString
+  :skip: SBDebugger_Initialize
+  :skip: SBDebugger_InitializeWithErrorHandling
+  :skip: SBDebugger_MemoryPressureDetected
+  :skip: SBDebugger_SetDefaultArchitecture
+  :skip: SBDebugger_SetInternalVariable
+  :skip: SBDebugger_StateAsCString
+  :skip: SBDebugger_StateIsRunningState
+  :skip: SBDebugger_StateIsStoppedState
+  :skip: SBDebugger_Terminate
+  :skip: SBEvent_GetCStringFromEvent
+  :skip: SBFileSpec_ResolvePath
+  :skip: SBFile_MakeBorrowed
+  :skip: SBFile_MakeBorrowedForcingIOMethods
+  :skip: SBFile_MakeForcingIOMethods
+  :skip: SBHostOS_GetLLDBPath
+  :skip: SBHostOS_GetLLDBPythonPath
+  :skip: SBHostOS_GetProgramFileSpec
+  :skip: SBHostOS_GetUserHomeDirectory
+  :skip: SBHostOS_ThreadCancel
+  :skip: SBHostOS_ThreadCreate
+  :skip: SBHostOS_ThreadCreated
+  :skip: SBHostOS_ThreadDetach
+  :skip: SBHostOS_ThreadJoin
+  :skip: SBLanguageRuntime_GetLanguageTypeFromString
+  :skip: SBLanguageRuntime_GetNameForLanguageType
+  :skip: SBModuleSpecList_GetModuleSpecifications
+  :skip: SBModule_GarbageCollectAllocatedModules
+  :skip: SBModule_GetNumberAllocatedModules
+  :skip: SBPlatform_GetHostPlatform
+  :skip: SBProcess_EventIsProcessEvent
+  :skip: SBProcess_EventIsStructuredDataEvent
+  :skip: SBProcess_GetBroadcasterClassName
+  :skip: SBProcess_GetInterruptedFromEvent
+  :skip: SBProcess_GetNumRestartedReasonsFromEvent
+  :skip: SBProcess_GetProcessFromEvent
+  :skip: SBProcess_GetRestartedFromEvent
+  :skip: SBProcess_GetRestartedReasonAtIndexFromEvent
+  :skip: SBProcess_GetStateFromEvent
+  :skip: SBProcess_GetStructuredDataFromEvent
+  :skip: SBReproducer_Capture
+  :skip: SBReproducer_PassiveReplay
+  :skip: SBReproducer_SetAutoGenerate
+  :skip: SBReproducer_SetWorkingDirectory
+  :skip: SBTarget_EventIsTargetEvent
+  :skip: SBTarget_GetBroadcasterClassName
+  :skip: SBTarget_GetModuleAtIndexFromEvent
+  :skip: SBTarget_GetNumModulesFromEvent
+  :skip: SBTarget_GetTargetFromEvent
+  :skip: SBThread_EventIsThreadEvent
+  :skip: SBThread_GetBroadcasterClassName
+  :skip: SBThread_GetStackFrameFromEvent
+  :skip: SBThread_GetThreadFromEvent
+  :skip: SBTypeSummary_CreateWithFunctionName
+  :skip: SBTypeSummary_CreateWithScriptCode
+  :skip: SBTypeSummary_CreateWithSummaryString
+  :skip: SBTypeSynthetic_CreateWithClassName
+  :skip: SBTypeSynthetic_CreateWithScriptCode
+  :skip: SBWatchpoint_EventIsWatchpointEvent
+  :skip: SBWatchpoint_GetWatchpointEventTypeFromEvent
+  :skip: SBWatchpoint_GetWatchpointFromEvent
+  :skip: command
+  :skip: in_range
+  :skip: is_numeric_type
+  :skip: lldb_iter