Index: include/llvm/IR/IRBuilder.h
===================================================================
--- include/llvm/IR/IRBuilder.h
+++ include/llvm/IR/IRBuilder.h
@@ -550,6 +550,9 @@
   /// assume that the provided condition will be true.
   CallInst *CreateAssumption(Value *Cond);
 
+  /// \brief Create an noalias intrinsic.
+  Instruction *CreateNoAliasPointer(Value *Ptr, MDNode *ScopeTag);
+
   /// \brief Create a call to the experimental.gc.statepoint intrinsic to
   /// start a new statepoint sequence.
   CallInst *CreateGCStatepointCall(uint64_t ID, uint32_t NumPatchBytes,
Index: lib/IR/IRBuilder.cpp
===================================================================
--- lib/IR/IRBuilder.cpp
+++ lib/IR/IRBuilder.cpp
@@ -17,6 +17,7 @@
 #include "llvm/IR/GlobalVariable.h"
 #include "llvm/IR/Intrinsics.h"
 #include "llvm/IR/LLVMContext.h"
+#include "llvm/IR/Metadata.h"
 #include "llvm/IR/Statepoint.h"
 using namespace llvm;
 
@@ -342,6 +343,32 @@
   return createCallHelper(FnAssume, Ops, this);
 }
 
+Instruction *IRBuilderBase::CreateNoAliasPointer(Value *Ptr, MDNode *ScopeTag) {
+  // FIXME: We can currently mangle just about everything, but not literal
+  // structs (for those, bitcast to i8*).
+  Value *CPtr = Ptr;
+  if (auto *STyp =
+        dyn_cast<StructType>(CPtr->getType()->getPointerElementType())) {
+    if (STyp->isLiteral())
+      CPtr = getCastedInt8PtrValue(CPtr);
+  }
+
+  Type *Types[] = { CPtr->getType() };
+  Value *Ops[] = { CPtr, MetadataAsValue::get(Context, ScopeTag) };
+  Module *M = BB->getModule();
+  Value *FnNoAlias = Intrinsic::getDeclaration(M, Intrinsic::noalias, Types);
+  Instruction *Ret = createCallHelper(FnNoAlias, Ops, this);
+
+  if (Ret->getType() != Ptr->getType()) {
+    BitCastInst *BCI = new BitCastInst(Ret, Ptr->getType(), "");
+    BB->getInstList().insert(InsertPt, BCI);
+    SetInstDebugLocation(BCI);
+    Ret = BCI;
+  }
+
+  return Ret;
+}
+
 /// \brief Create a call to a Masked Load intrinsic.
 /// \p Ptr      - base pointer for the load
 /// \p Align    - alignment of the source location
Index: unittests/IR/IRBuilderTest.cpp
===================================================================
--- unittests/IR/IRBuilderTest.cpp
+++ unittests/IR/IRBuilderTest.cpp
@@ -48,6 +48,30 @@
   GlobalVariable *GV;
 };
 
+TEST_F(IRBuilderTest, NoAlias) {
+  IRBuilder<> Builder(BB);
+  AllocaInst *Var1 = Builder.CreateAlloca(Builder.getInt8Ty());
+
+  MDBuilder MDB(BB->getContext());
+  MDNode *NewDomain =
+    MDB.createAnonymousAliasScopeDomain("Test Domain");
+  MDNode *AScope =
+    MDB.createAnonymousAliasScope(NewDomain, "Test Scope");
+
+  CallInst *NAP = cast<CallInst>(Builder.CreateNoAliasPointer(Var1, AScope));
+
+  EXPECT_EQ(NAP->getArgOperand(0), Var1);
+  EXPECT_EQ(cast<MetadataAsValue>(NAP->getArgOperand(1))->getMetadata(),
+            AScope);
+
+  IntrinsicInst *II_NAP = dyn_cast<IntrinsicInst>(NAP);
+  ASSERT_TRUE(II_NAP != nullptr);
+  EXPECT_EQ(II_NAP->getIntrinsicID(), Intrinsic::noalias);
+
+  EXPECT_TRUE(NAP->onlyAccessesArgMemory());
+  EXPECT_TRUE(NAP->doesNotThrow());
+}
+
 TEST_F(IRBuilderTest, Lifetime) {
   IRBuilder<> Builder(BB);
   AllocaInst *Var1 = Builder.CreateAlloca(Builder.getInt8Ty());