diff --git a/libcxx/lib/abi/CMakeLists.txt b/libcxx/lib/abi/CMakeLists.txt
--- a/libcxx/lib/abi/CMakeLists.txt
+++ b/libcxx/lib/abi/CMakeLists.txt
@@ -1,43 +1,75 @@
 
-if (DEFINED TARGET_TRIPLE)
-    if (TARGET_TRIPLE MATCHES "darwin")
-        # Ignore the major, minor, and patchlevel versions of darwin targets.
-        string(REGEX REPLACE "darwin[0-9]+\\.[0-9]+\\.[0-9]+" "darwin"
-               GENERIC_TARGET_TRIPLE "${TARGET_TRIPLE}")
-    elseif(TARGET_TRIPLE MATCHES "freebsd")
-        # Ignore the major and minor versions of freebsd targets.
-        string(REGEX REPLACE "freebsd[0-9]+\\.[0-9]+" "freebsd"
-               GENERIC_TARGET_TRIPLE "${TARGET_TRIPLE}")
-    else()
-        set(GENERIC_TARGET_TRIPLE "${TARGET_TRIPLE}")
-    endif()
-endif()
+# This function generates a "unique" identifier based on various properties
+# given as arguments. The idea is to encode all ABI-affecting properties
+# in that identifier, so that we can store ABI information and associate it
+# to a specific ABI configuration.
+#
+# Right now, this is done by using the ABI identifier as the filename containing
+# the list of symbols exported by libc++ for that configuration, however we could
+# make it more sophisticated if the number of ABI-affecting parameters grew.
+function(cxx_abi_list_identifier result triple abi_library abi_version unstable exceptions new_delete_in_libcxx)
+  set(abi_properties)
+
+  if ("${triple}" MATCHES "darwin")
+    # Ignore the major, minor, and patchlevel versions of darwin targets.
+    string(REGEX REPLACE "darwin[0-9]+\\.[0-9]+\\.[0-9]+" "darwin" triple "${triple}")
+  elseif("${triple}" MATCHES "freebsd")
+    # Ignore the major and minor versions of freebsd targets.
+    string(REGEX REPLACE "freebsd[0-9]+\\.[0-9]+" "freebsd" triple "${triple}")
+  endif()
+  list(APPEND abi_properties "${triple}")
+  list(APPEND abi_properties "${abi_library}")
+  list(APPEND abi_properties "v${abi_version}")
+  if (${unstable})
+    list(APPEND abi_properties "unstable")
+  else()
+    list(APPEND abi_properties "stable")
+  endif()
+  if (${exceptions})
+    list(APPEND abi_properties "exceptions")
+  else()
+    list(APPEND abi_properties "noexceptions")
+  endif()
+  if (${new_delete_in_libcxx})
+    list(APPEND abi_properties "new_in_libcxx")
+  else()
+    list(APPEND abi_properties "no_new_in_libcxx")
+  endif()
+
+  list(JOIN abi_properties "." tmp)
+  set(${result} "${tmp}" PARENT_SCOPE)
+endfunction()
+
+cxx_abi_list_identifier(abi_list_identifier
+  "${TARGET_TRIPLE}"
+  "${LIBCXX_CXX_ABI_LIBNAME}"
+  "${LIBCXX_ABI_VERSION}"
+  "${LIBCXX_ABI_UNSTABLE}"
+  "${LIBCXX_ENABLE_EXCEPTIONS}"
+  "${LIBCXX_ENABLE_NEW_DELETE_DEFINITIONS}"
+)
 
-# Detect if we are building in the same configuration used to generate
-# the abilist files.
-set(ABILIST_FILE "${CMAKE_CURRENT_LIST_DIR}/${GENERIC_TARGET_TRIPLE}.v${LIBCXX_ABI_VERSION}.abilist")
-if (EXISTS "${ABILIST_FILE}"
-    AND TARGET cxx_shared
-    AND ("${LIBCXX_CXX_ABI_LIBNAME}" STREQUAL "libcxxabi" OR
-         (APPLE AND "${LIBCXX_CXX_ABI_LIBNAME}" STREQUAL "default"))
-    AND NOT LIBCXX_ABI_UNSTABLE
-    AND LIBCXX_ENABLE_EXCEPTIONS
-    AND NOT LIBCXX_ENABLE_NEW_DELETE_DEFINITIONS)
+if (TARGET cxx_shared)
+  set(abi_list_file "${CMAKE_CURRENT_SOURCE_DIR}/${abi_list_identifier}.abilist")
+
+  if (EXISTS "${abi_list_file}")
     add_custom_target(check-cxx-abilist
-            ${Python3_EXECUTABLE} "${LIBCXX_SOURCE_DIR}/utils/sym_diff.py"
-                --only-stdlib-symbols
-                --strict ${ABILIST_FILE}
-                $<TARGET_SONAME_FILE:cxx_shared>
-            DEPENDS cxx_shared
-            COMMENT "Testing ABI compatibility...")
-
-    add_custom_target(generate-cxx-abilist
-        COMMAND ${Python3_EXECUTABLE} "${LIBCXX_SOURCE_DIR}/utils/generate_abi_list.py"
-                 --output "${ABILIST_FILE}"
-                 "$<TARGET_SONAME_FILE:cxx_shared>"
-        DEPENDS cxx_shared
-        COMMENT "Generating the ABI list for the current configuration")
+      "${Python3_EXECUTABLE}" "${LIBCXX_SOURCE_DIR}/utils/sym_diff.py"
+          --only-stdlib-symbols
+          --strict "${abi_list_file}"
+          $<TARGET_SONAME_FILE:cxx_shared>
+      DEPENDS cxx_shared
+      COMMENT "Testing libc++'s exported symbols against the ABI list")
+  else()
+
+  endif()
+
+  add_custom_target(generate-cxx-abilist
+    COMMAND "${Python3_EXECUTABLE}" "${LIBCXX_SOURCE_DIR}/utils/generate_abi_list.py"
+            --output "${abi_list_file}"
+            "$<TARGET_SONAME_FILE:cxx_shared>"
+    DEPENDS cxx_shared
+    COMMENT "Generating the ABI list file for configuration ${abi_list_identifier}")
 else()
-    message(STATUS "there is no pre-generated ABI list for the requested libc++ configuration. "
-            "check-cxx-abilist target is not supported")
+  message(STATUS "Not building a shared library for libc++ -- the ABI list targets will not be available.")
 endif()
diff --git a/libcxx/lib/abi/x86_64-apple-darwin.v1.abilist b/libcxx/lib/abi/x86_64-apple-darwin.libcxxabi.v1.stable.exceptions.no_new_in_libcxx.abilist
rename from libcxx/lib/abi/x86_64-apple-darwin.v1.abilist
rename to libcxx/lib/abi/x86_64-apple-darwin.libcxxabi.v1.stable.exceptions.no_new_in_libcxx.abilist
diff --git a/libcxx/lib/abi/x86_64-unknown-linux-gnu.v1.abilist b/libcxx/lib/abi/x86_64-unknown-linux-gnu.libcxxabi.v1.stable.exceptions.no_new_in_libcxx.abilist
rename from libcxx/lib/abi/x86_64-unknown-linux-gnu.v1.abilist
rename to libcxx/lib/abi/x86_64-unknown-linux-gnu.libcxxabi.v1.stable.exceptions.no_new_in_libcxx.abilist
diff --git a/libcxx/utils/ci/run-buildbot b/libcxx/utils/ci/run-buildbot
--- a/libcxx/utils/ci/run-buildbot
+++ b/libcxx/utils/ci/run-buildbot
@@ -88,6 +88,13 @@
     ninja -C "${BUILD_DIR}" install-cxx install-cxxabi
 }
 
+# TODO: The goal is to test this against all configurations. We should also move
+#       this to the Lit test suite instead of being a separate CMake target.
+function check-abi-list() {
+    echo "+++ Running the libc++ ABI list test"
+    ninja -C "${BUILD_DIR}" check-cxx-abilist
+}
+
 function check-cxx-benchmarks() {
     echo "--- Running the benchmarks"
     ninja -C "${BUILD_DIR}" check-cxx-benchmarks
@@ -100,6 +107,7 @@
     clean
     generate-cmake -C "${MONOREPO_ROOT}/libcxx/cmake/caches/Generic-cxx03.cmake"
     check-cxx-cxxabi
+    check-abi-list
 ;;
 generic-cxx11)
     export CC=clang
@@ -107,6 +115,7 @@
     clean
     generate-cmake -C "${MONOREPO_ROOT}/libcxx/cmake/caches/Generic-cxx11.cmake"
     check-cxx-cxxabi
+    check-abi-list
 ;;
 generic-cxx14)
     export CC=clang
@@ -114,6 +123,7 @@
     clean
     generate-cmake -C "${MONOREPO_ROOT}/libcxx/cmake/caches/Generic-cxx14.cmake"
     check-cxx-cxxabi
+    check-abi-list
 ;;
 generic-cxx17)
     export CC=clang
@@ -121,6 +131,7 @@
     clean
     generate-cmake -C "${MONOREPO_ROOT}/libcxx/cmake/caches/Generic-cxx17.cmake"
     check-cxx-cxxabi
+    check-abi-list
 ;;
 generic-cxx2a)
     export CC=clang
@@ -128,6 +139,7 @@
     clean
     generate-cmake -C "${MONOREPO_ROOT}/libcxx/cmake/caches/Generic-cxx2a.cmake"
     check-cxx-cxxabi
+    check-abi-list
 ;;
 generic-noexceptions)
     export CC=clang
@@ -293,6 +305,7 @@
           -DLLVM_ENABLE_PROJECTS="libcxx;libcxxabi;libunwind"
 
     check-cxx-cxxabi
+    check-abi-list
 ;;
 legacy-standalone)
     export CC=clang