diff --git a/mlir/lib/Bindings/Python/Pass.cpp b/mlir/lib/Bindings/Python/Pass.cpp
--- a/mlir/lib/Bindings/Python/Pass.cpp
+++ b/mlir/lib/Bindings/Python/Pass.cpp
@@ -60,6 +60,17 @@
           "Parse a textual pass-pipeline and return a top-level PassManager "
           "that can be applied on a Module. Throw a ValueError if the pipeline "
           "can't be parsed")
+      .def(
+          "run",
+          [](PyPassManager &passManager, PyModule &module) {
+            MlirLogicalResult status =
+                mlirPassManagerRun(passManager.get(), module.get());
+            if (mlirLogicalResultIsFailure(status))
+              throw SetPyError(PyExc_RuntimeError,
+                               "Failure while executing pass pipeline.");
+          },
+          "Run the pass manager on the provided module, throw a RuntimeError "
+          "on failure.")
       .def(
           "__str__",
           [](PyPassManager &self) {
diff --git a/mlir/test/Bindings/Python/pass_manager.py b/mlir/test/Bindings/Python/pass_manager.py
--- a/mlir/test/Bindings/Python/pass_manager.py
+++ b/mlir/test/Bindings/Python/pass_manager.py
@@ -5,8 +5,7 @@
 from mlir.passmanager import *
 
 # Log everything to stderr and flush so that we have a unified stream to match
-# errors emitted by MLIR to stderr. TODO: this shouldn't be needed when
-# everything is plumbed.
+# errors/info emitted by MLIR to stderr.
 def log(*args):
   print(*args, file=sys.stderr)
   sys.stderr.flush()
@@ -52,3 +51,18 @@
     else:
       log("Exception not produced")
 run(testParseFail)
+
+
+# Verify that a pass manager can execute on IR
+# CHECK-LABEL: TEST: testRun
+def testRunPipeline():
+  with Context():
+    pm = PassManager.parse("print-op-stats")
+    module = Module.parse(r"""func @successfulParse() { return }""")
+    pm.run(module)
+# CHECK: Operations encountered:
+# CHECK: func              , 1
+# CHECK: module            , 1
+# CHECK: module_terminator , 1
+# CHECK: std.return        , 1
+run(testRunPipeline)