diff --git a/compiler-rt/lib/msan/tests/CMakeLists.txt b/compiler-rt/lib/msan/tests/CMakeLists.txt
--- a/compiler-rt/lib/msan/tests/CMakeLists.txt
+++ b/compiler-rt/lib/msan/tests/CMakeLists.txt
@@ -25,8 +25,6 @@
   ../../../include/sanitizer/msan_interface.h
   )
 set(MSAN_UNITTEST_COMMON_CFLAGS
-  -nostdinc++
-  -isystem ${COMPILER_RT_LIBCXX_PATH}/include
   ${COMPILER_RT_UNITTEST_CFLAGS}
   ${COMPILER_RT_GTEST_CFLAGS}
   -I${COMPILER_RT_SOURCE_DIR}/include
@@ -43,8 +41,6 @@
   -Werror=sign-compare
   -Wno-gnu-zero-variadic-macro-arguments
 )
-# Remove -stdlib= which is unused when passing -nostdinc++.
-string(REGEX REPLACE "-stdlib=[a-zA-Z+]*" "" CMAKE_CXX_FLAGS ${CMAKE_CXX_FLAGS})
 
 set(MSAN_UNITTEST_INSTRUMENTED_CFLAGS
   ${MSAN_UNITTEST_COMMON_CFLAGS}