diff --git a/clang/include/clang/Basic/BuiltinsWebAssembly.def b/clang/include/clang/Basic/BuiltinsWebAssembly.def
--- a/clang/include/clang/Basic/BuiltinsWebAssembly.def
+++ b/clang/include/clang/Basic/BuiltinsWebAssembly.def
@@ -171,8 +171,17 @@
 TARGET_BUILTIN(__builtin_wasm_narrow_s_i16x8_i32x4, "V8sV4iV4i", "nc", "simd128")
 TARGET_BUILTIN(__builtin_wasm_narrow_u_i16x8_i32x4, "V8UsV4UiV4Ui", "nc", "simd128")
 
-TARGET_BUILTIN(__builtin_wasm_load32_zero, "V4ii*", "nU", "simd128")
-TARGET_BUILTIN(__builtin_wasm_load64_zero, "V2LLiLLi*", "nU", "simd128")
+TARGET_BUILTIN(__builtin_wasm_load32_zero, "V4ii*", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_load64_zero, "V2LLiLLi*", "n", "simd128")
+
+TARGET_BUILTIN(__builtin_wasm_load8_lane, "V16ScSc*V16ScIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_load16_lane, "V8ss*V8sIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_load32_lane, "V4ii*V4iIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_load64_lane, "V2LLiLLi*V2LLiIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_store8_lane, "vSc*V16ScIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_store16_lane, "vs*V8sIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_store32_lane, "vi*V4iIi", "n", "simd128")
+TARGET_BUILTIN(__builtin_wasm_store64_lane, "vLLi*V2LLiIi", "n", "simd128")
 
 #undef BUILTIN
 #undef TARGET_BUILTIN
diff --git a/clang/lib/CodeGen/CGBuiltin.cpp b/clang/lib/CodeGen/CGBuiltin.cpp
--- a/clang/lib/CodeGen/CGBuiltin.cpp
+++ b/clang/lib/CodeGen/CGBuiltin.cpp
@@ -16711,6 +16711,52 @@
     Function *Callee = CGM.getIntrinsic(Intrinsic::wasm_load64_zero);
     return Builder.CreateCall(Callee, {Ptr});
   }
+  case WebAssembly::BI__builtin_wasm_load8_lane:
+  case WebAssembly::BI__builtin_wasm_load16_lane:
+  case WebAssembly::BI__builtin_wasm_load32_lane:
+  case WebAssembly::BI__builtin_wasm_load64_lane:
+  case WebAssembly::BI__builtin_wasm_store8_lane:
+  case WebAssembly::BI__builtin_wasm_store16_lane:
+  case WebAssembly::BI__builtin_wasm_store32_lane:
+  case WebAssembly::BI__builtin_wasm_store64_lane: {
+    Value *Ptr = EmitScalarExpr(E->getArg(0));
+    Value *Vec = EmitScalarExpr(E->getArg(1));
+    Optional<llvm::APSInt> LaneIdxConst =
+        E->getArg(2)->getIntegerConstantExpr(getContext());
+    assert(LaneIdxConst && "Constant arg isn't actually constant?");
+    Value *LaneIdx = llvm::ConstantInt::get(getLLVMContext(), *LaneIdxConst);
+    unsigned IntNo;
+    switch (BuiltinID) {
+    case WebAssembly::BI__builtin_wasm_load8_lane:
+      IntNo = Intrinsic::wasm_load8_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_load16_lane:
+      IntNo = Intrinsic::wasm_load16_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_load32_lane:
+      IntNo = Intrinsic::wasm_load32_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_load64_lane:
+      IntNo = Intrinsic::wasm_load64_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_store8_lane:
+      IntNo = Intrinsic::wasm_store8_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_store16_lane:
+      IntNo = Intrinsic::wasm_store16_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_store32_lane:
+      IntNo = Intrinsic::wasm_store32_lane;
+      break;
+    case WebAssembly::BI__builtin_wasm_store64_lane:
+      IntNo = Intrinsic::wasm_store64_lane;
+      break;
+    default:
+      llvm_unreachable("unexpected builtin ID");
+    }
+    Function *Callee = CGM.getIntrinsic(IntNo);
+    return Builder.CreateCall(Callee, {Ptr, Vec, LaneIdx});
+  }
   case WebAssembly::BI__builtin_wasm_shuffle_v8x16: {
     Value *Ops[18];
     size_t OpIdx = 0;
diff --git a/clang/test/CodeGen/builtins-wasm.c b/clang/test/CodeGen/builtins-wasm.c
--- a/clang/test/CodeGen/builtins-wasm.c
+++ b/clang/test/CodeGen/builtins-wasm.c
@@ -284,6 +284,62 @@
   // WEBASSEMBLY-NEXT: ret
 }
 
+i8x16 load8_lane(signed char *p, i8x16 v) {
+  return __builtin_wasm_load8_lane(p, v, 0);
+  // WEBASSEMBLY: tail call <16 x i8> @llvm.wasm.load8.lane(
+  // WEBASSEMBLY-SAME: i8* %p, <16 x i8> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+i16x8 load16_lane(short *p, i16x8 v) {
+  return __builtin_wasm_load16_lane(p, v, 0);
+  // WEBASSEMBLY: tail call <8 x i16> @llvm.wasm.load16.lane(
+  // WEBASSEMBLY-SAME: i16* %p, <8 x i16> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+i32x4 load32_lane(int *p, i32x4 v) {
+  return __builtin_wasm_load32_lane(p, v, 0);
+  // WEBASSEMBLY: tail call <4 x i32> @llvm.wasm.load32.lane(
+  // WEBASSEMBLY-SAME: i32* %p, <4 x i32> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+i64x2 load64_lane(long long *p, i64x2 v) {
+  return __builtin_wasm_load64_lane(p, v, 0);
+  // WEBASSEMBLY: tail call <2 x i64> @llvm.wasm.load64.lane(
+  // WEBASSEMBLY-SAME: i64* %p, <2 x i64> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+void store8_lane(signed char *p, i8x16 v) {
+  __builtin_wasm_store8_lane(p, v, 0);
+  // WEBASSEMBLY: call void @llvm.wasm.store8.lane(
+  // WEBASSEMBLY-SAME: i8* %p, <16 x i8> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+void store16_lane(short *p, i16x8 v) {
+  __builtin_wasm_store16_lane(p, v, 0);
+  // WEBASSEMBLY: call void @llvm.wasm.store16.lane(
+  // WEBASSEMBLY-SAME: i16* %p, <8 x i16> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+void store32_lane(int *p, i32x4 v) {
+  __builtin_wasm_store32_lane(p, v, 0);
+  // WEBASSEMBLY: call void @llvm.wasm.store32.lane(
+  // WEBASSEMBLY-SAME: i32* %p, <4 x i32> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
+void store64_lane(long long *p, i64x2 v) {
+  __builtin_wasm_store64_lane(p, v, 0);
+  // WEBASSEMBLY: call void @llvm.wasm.store64.lane(
+  // WEBASSEMBLY-SAME: i64* %p, <2 x i64> %v, i32 0)
+  // WEBASSEMBLY-NEXT: ret
+}
+
 i8x16 add_saturate_s_i8x16(i8x16 x, i8x16 y) {
   return __builtin_wasm_add_saturate_s_i8x16(x, y);
   // WEBASSEMBLY: call <16 x i8> @llvm.sadd.sat.v16i8(
diff --git a/llvm/include/llvm/IR/IntrinsicsWebAssembly.td b/llvm/include/llvm/IR/IntrinsicsWebAssembly.td
--- a/llvm/include/llvm/IR/IntrinsicsWebAssembly.td
+++ b/llvm/include/llvm/IR/IntrinsicsWebAssembly.td
@@ -208,6 +208,52 @@
             [IntrReadMem, IntrArgMemOnly],
              "", [SDNPMemOperand]>;
 
+// These intrinsics do not mark their lane index arguments as immediate because
+// that changes the corresponding SDNode from ISD::Constant to
+// ISD::TargetConstant, which would require extra complications in the ISel
+// tablegen patterns. TODO: Replace these intrinsic with normal ISel patterns
+// once the load_lane instructions are merged to the proposal.
+def int_wasm_load8_lane :
+  Intrinsic<[llvm_v16i8_ty],
+            [LLVMPointerType<llvm_i8_ty>, llvm_v16i8_ty, llvm_i32_ty],
+            [IntrReadMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_load16_lane :
+  Intrinsic<[llvm_v8i16_ty],
+            [LLVMPointerType<llvm_i16_ty>, llvm_v8i16_ty, llvm_i32_ty],
+            [IntrReadMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_load32_lane :
+  Intrinsic<[llvm_v4i32_ty],
+            [LLVMPointerType<llvm_i32_ty>, llvm_v4i32_ty, llvm_i32_ty],
+            [IntrReadMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_load64_lane :
+  Intrinsic<[llvm_v2i64_ty],
+            [LLVMPointerType<llvm_i64_ty>, llvm_v2i64_ty, llvm_i32_ty],
+            [IntrReadMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_store8_lane :
+  Intrinsic<[],
+            [LLVMPointerType<llvm_i8_ty>, llvm_v16i8_ty, llvm_i32_ty],
+            [IntrWriteMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_store16_lane :
+  Intrinsic<[],
+            [LLVMPointerType<llvm_i16_ty>, llvm_v8i16_ty, llvm_i32_ty],
+            [IntrWriteMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_store32_lane :
+  Intrinsic<[],
+            [LLVMPointerType<llvm_i32_ty>, llvm_v4i32_ty, llvm_i32_ty],
+            [IntrWriteMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+def int_wasm_store64_lane :
+  Intrinsic<[],
+            [LLVMPointerType<llvm_i64_ty>, llvm_v2i64_ty, llvm_i32_ty],
+            [IntrWriteMem, IntrArgMemOnly],
+            "", [SDNPMemOperand]>;
+
 //===----------------------------------------------------------------------===//
 // Thread-local storage intrinsics
 //===----------------------------------------------------------------------===//
diff --git a/llvm/lib/Target/WebAssembly/AsmParser/WebAssemblyAsmParser.cpp b/llvm/lib/Target/WebAssembly/AsmParser/WebAssemblyAsmParser.cpp
--- a/llvm/lib/Target/WebAssembly/AsmParser/WebAssemblyAsmParser.cpp
+++ b/llvm/lib/Target/WebAssembly/AsmParser/WebAssemblyAsmParser.cpp
@@ -421,6 +421,12 @@
           return error("Expected integer constant");
         parseSingleInteger(false, Operands);
       } else {
+        // v128.{load,store}{8,16,32,64}_lane has both a memarg and a lane
+        // index. We need to avoid parsing an extra alignment operand for the
+        // lane index.
+        auto IsLoadStoreLane = InstName.find("_lane") != StringRef::npos;
+        if (IsLoadStoreLane && Operands.size() == 4)
+          return false;
         // Alignment not specified (or atomics, must use default alignment).
         // We can't just call WebAssembly::GetDefaultP2Align since we don't have
         // an opcode until after the assembly matcher, so set a default to fix
diff --git a/llvm/lib/Target/WebAssembly/MCTargetDesc/WebAssemblyMCTargetDesc.h b/llvm/lib/Target/WebAssembly/MCTargetDesc/WebAssemblyMCTargetDesc.h
--- a/llvm/lib/Target/WebAssembly/MCTargetDesc/WebAssemblyMCTargetDesc.h
+++ b/llvm/lib/Target/WebAssembly/MCTargetDesc/WebAssemblyMCTargetDesc.h
@@ -177,7 +177,9 @@
   WASM_LOAD_STORE(ATOMIC_RMW8_U_CMPXCHG_I32)
   WASM_LOAD_STORE(ATOMIC_RMW8_U_CMPXCHG_I64)
   WASM_LOAD_STORE(LOAD_SPLAT_v8x16)
-    return 0;
+  WASM_LOAD_STORE(LOAD_LANE_v16i8)
+  WASM_LOAD_STORE(STORE_LANE_v16i8)
+  return 0;
   WASM_LOAD_STORE(LOAD16_S_I32)
   WASM_LOAD_STORE(LOAD16_U_I32)
   WASM_LOAD_STORE(LOAD16_S_I64)
@@ -203,7 +205,9 @@
   WASM_LOAD_STORE(ATOMIC_RMW16_U_CMPXCHG_I32)
   WASM_LOAD_STORE(ATOMIC_RMW16_U_CMPXCHG_I64)
   WASM_LOAD_STORE(LOAD_SPLAT_v16x8)
-    return 1;
+  WASM_LOAD_STORE(LOAD_LANE_v8i16)
+  WASM_LOAD_STORE(STORE_LANE_v8i16)
+  return 1;
   WASM_LOAD_STORE(LOAD_I32)
   WASM_LOAD_STORE(LOAD_F32)
   WASM_LOAD_STORE(STORE_I32)
@@ -233,7 +237,9 @@
   WASM_LOAD_STORE(ATOMIC_WAIT_I32)
   WASM_LOAD_STORE(LOAD_SPLAT_v32x4)
   WASM_LOAD_STORE(LOAD_ZERO_v4i32)
-    return 2;
+  WASM_LOAD_STORE(LOAD_LANE_v4i32)
+  WASM_LOAD_STORE(STORE_LANE_v4i32)
+  return 2;
   WASM_LOAD_STORE(LOAD_I64)
   WASM_LOAD_STORE(LOAD_F64)
   WASM_LOAD_STORE(STORE_I64)
@@ -256,7 +262,9 @@
   WASM_LOAD_STORE(LOAD_EXTEND_S_v2i64)
   WASM_LOAD_STORE(LOAD_EXTEND_U_v2i64)
   WASM_LOAD_STORE(LOAD_ZERO_v2i64)
-    return 3;
+  WASM_LOAD_STORE(LOAD_LANE_v2i64)
+  WASM_LOAD_STORE(STORE_LANE_v2i64)
+  return 3;
   WASM_LOAD_STORE(LOAD_V128)
   WASM_LOAD_STORE(STORE_V128)
     return 4;
diff --git a/llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp b/llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
--- a/llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
+++ b/llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
@@ -685,6 +685,56 @@
     Info.align = Info.memVT == MVT::i32 ? Align(4) : Align(8);
     Info.flags = MachineMemOperand::MOLoad;
     return true;
+  case Intrinsic::wasm_load8_lane:
+  case Intrinsic::wasm_load16_lane:
+  case Intrinsic::wasm_load32_lane:
+  case Intrinsic::wasm_load64_lane:
+  case Intrinsic::wasm_store8_lane:
+  case Intrinsic::wasm_store16_lane:
+  case Intrinsic::wasm_store32_lane:
+  case Intrinsic::wasm_store64_lane: {
+    MVT MemVT;
+    Align MemAlign;
+    switch (Intrinsic) {
+    case Intrinsic::wasm_load8_lane:
+    case Intrinsic::wasm_store8_lane:
+      MemVT = MVT::i8;
+      MemAlign = Align(1);
+      break;
+    case Intrinsic::wasm_load16_lane:
+    case Intrinsic::wasm_store16_lane:
+      MemVT = MVT::i16;
+      MemAlign = Align(2);
+      break;
+    case Intrinsic::wasm_load32_lane:
+    case Intrinsic::wasm_store32_lane:
+      MemVT = MVT::i32;
+      MemAlign = Align(4);
+      break;
+    case Intrinsic::wasm_load64_lane:
+    case Intrinsic::wasm_store64_lane:
+      MemVT = MVT::i64;
+      MemAlign = Align(8);
+      break;
+    default:
+      llvm_unreachable("unexpected intrinsic");
+    }
+    if (Intrinsic == Intrinsic::wasm_load8_lane ||
+        Intrinsic == Intrinsic::wasm_load16_lane ||
+        Intrinsic == Intrinsic::wasm_load32_lane ||
+        Intrinsic == Intrinsic::wasm_load64_lane) {
+      Info.opc = ISD::INTRINSIC_W_CHAIN;
+      Info.flags = MachineMemOperand::MOLoad;
+    } else {
+      Info.opc = ISD::INTRINSIC_VOID;
+      Info.flags = MachineMemOperand::MOStore;
+    }
+    Info.ptrVal = I.getArgOperand(0);
+    Info.memVT = MemVT;
+    Info.offset = 0;
+    Info.align = MemAlign;
+    return true;
+  }
   default:
     return false;
   }
diff --git a/llvm/lib/Target/WebAssembly/WebAssemblyInstrSIMD.td b/llvm/lib/Target/WebAssembly/WebAssemblyInstrSIMD.td
--- a/llvm/lib/Target/WebAssembly/WebAssemblyInstrSIMD.td
+++ b/llvm/lib/Target/WebAssembly/WebAssemblyInstrSIMD.td
@@ -53,7 +53,7 @@
          "v128.load\t$off$p2align", 0>;
 }
 
-// Def load and store patterns from WebAssemblyInstrMemory.td for vector types
+// Def load patterns from WebAssemblyInstrMemory.td for vector types
 foreach vec_t = [v16i8, v8i16, v4i32, v2i64, v4f32, v2f64] in {
 defm : LoadPatNoOffset<vec_t, load, "LOAD_V128">;
 defm : LoadPatImmOff<vec_t, load, regPlusImm, "LOAD_V128">;
@@ -201,6 +201,51 @@
 defm : LoadPatGlobalAddrOffOnly<v4i32, int_wasm_load32_zero, "LOAD_ZERO_v4i32">;
 defm : LoadPatGlobalAddrOffOnly<v2i64, int_wasm_load64_zero, "LOAD_ZERO_v2i64">;
 
+// Load lane
+multiclass SIMDLoadLane<ValueType vec_t, string name, bits<32> simdop> {
+  let mayLoad = 1, UseNamedOperandTable = 1 in {
+  defm LOAD_LANE_#vec_t#_A32 :
+    SIMD_I<(outs V128:$dst),
+           (ins P2Align:$p2align, offset32_op:$off, vec_i8imm_op:$idx,
+                I32:$addr, V128:$vec),
+           (outs), (ins P2Align:$p2align, offset32_op:$off, vec_i8imm_op:$idx),
+           [], name#"\t$dst, ${off}(${addr})$p2align, $vec, $idx",
+           name#"\t$off$p2align, $idx", simdop>;
+  defm LOAD_LANE_#vec_t#_A64 :
+    SIMD_I<(outs V128:$dst),
+           (ins P2Align:$p2align, offset64_op:$off, vec_i8imm_op:$idx,
+                I64:$addr, V128:$vec),
+           (outs), (ins P2Align:$p2align, offset64_op:$off, vec_i8imm_op:$idx),
+           [], name#"\t$dst, ${off}(${addr})$p2align, $vec, $idx",
+           name#"\t$off$p2align, $idx", simdop>;
+  } // mayLoad = 1, UseNamedOperandTable = 1
+}
+
+// TODO: Also support v4f32 and v2f64 once the instructions are merged
+// to the proposal
+defm "" : SIMDLoadLane<v16i8, "v128.load8_lane", 88>;
+defm "" : SIMDLoadLane<v8i16, "v128.load16_lane", 89>;
+defm "" : SIMDLoadLane<v4i32, "v128.load32_lane", 90>;
+defm "" : SIMDLoadLane<v2i64, "v128.load64_lane", 91>;
+
+// Select loads with no constant offset.
+multiclass LoadLanePatNoOffset<ValueType ty, PatFrag kind, ImmLeaf lane_imm_t> {
+  def : Pat<(ty (kind (i32 I32:$addr), (ty V128:$vec), (i32 lane_imm_t:$idx))),
+            (!cast<NI>("LOAD_LANE_"#ty#"_A32") 0, 0, imm:$idx, I32:$addr, V128:$vec)>,
+        Requires<[HasAddr32]>;
+  def : Pat<(ty (kind (i64 I64:$addr), (ty V128:$vec), (i32 lane_imm_t:$idx))),
+            (!cast<NI>("LOAD_LANE_"#ty#"_A64") 0, 0, imm:$idx, I64:$addr, V128:$vec)>,
+        Requires<[HasAddr64]>;
+}
+
+defm : LoadLanePatNoOffset<v16i8, int_wasm_load8_lane, LaneIdx16>;
+defm : LoadLanePatNoOffset<v8i16, int_wasm_load16_lane, LaneIdx8>;
+defm : LoadLanePatNoOffset<v4i32, int_wasm_load32_lane, LaneIdx4>;
+defm : LoadLanePatNoOffset<v2i64, int_wasm_load64_lane, LaneIdx2>;
+
+// TODO: Also support the other load patterns for load_lane once the instructions
+// are merged to the proposal.
+
 // Store: v128.store
 let mayStore = 1, UseNamedOperandTable = 1 in {
 defm STORE_V128_A32 :
@@ -214,8 +259,9 @@
          "v128.store\t${off}(${addr})$p2align, $vec",
          "v128.store\t$off$p2align", 11>;
 }
+
+// Def store patterns from WebAssemblyInstrMemory.td for vector types
 foreach vec_t = [v16i8, v8i16, v4i32, v2i64, v4f32, v2f64] in {
-// Def load and store patterns from WebAssemblyInstrMemory.td for vector types
 defm : StorePatNoOffset<vec_t, store, "STORE_V128">;
 defm : StorePatImmOff<vec_t, store, regPlusImm, "STORE_V128">;
 defm : StorePatImmOff<vec_t, store, or_is_add, "STORE_V128">;
@@ -223,6 +269,53 @@
 defm : StorePatGlobalAddrOffOnly<vec_t, store, "STORE_V128">;
 }
 
+// Store lane
+multiclass SIMDStoreLane<ValueType vec_t, string name, bits<32> simdop> {
+  let mayStore = 1, UseNamedOperandTable = 1 in {
+  defm STORE_LANE_#vec_t#_A32 :
+    SIMD_I<(outs),
+           (ins P2Align:$p2align, offset32_op:$off, vec_i8imm_op:$idx,
+                I32:$addr, V128:$vec),
+           (outs), (ins P2Align:$p2align, offset32_op:$off, vec_i8imm_op:$idx),
+           [], name#"\t${off}(${addr})$p2align, $vec, $idx",
+           name#"\t$off$p2align, $idx", simdop>;
+  defm STORE_LANE_#vec_t#_A64 :
+    SIMD_I<(outs V128:$dst),
+           (ins P2Align:$p2align, offset64_op:$off, vec_i8imm_op:$idx,
+                I64:$addr, V128:$vec),
+           (outs), (ins P2Align:$p2align, offset64_op:$off, vec_i8imm_op:$idx),
+           [], name#"\t${off}(${addr})$p2align, $vec, $idx",
+           name#"\t$off$p2align, $idx", simdop>;
+  } // mayStore = 1, UseNamedOperandTable = 1
+}
+
+// TODO: Also support v4f32 and v2f64 once the instructions are merged
+// to the proposal
+defm "" : SIMDStoreLane<v16i8, "v128.store8_lane", 92>;
+defm "" : SIMDStoreLane<v8i16, "v128.store16_lane", 93>;
+defm "" : SIMDStoreLane<v4i32, "v128.store32_lane", 94>;
+defm "" : SIMDStoreLane<v2i64, "v128.store64_lane", 95>;
+
+// Select stores with no constant offset.
+multiclass StoreLanePatNoOffset<ValueType ty, PatFrag kind, ImmLeaf lane_imm_t> {
+  def : Pat<(kind (i32 I32:$addr), (ty V128:$vec), (i32 lane_imm_t:$idx)),
+            (!cast<NI>("STORE_LANE_"#ty#"_A32")
+              0, 0, imm:$idx, I32:$addr, ty:$vec)>,
+        Requires<[HasAddr32]>;
+  def : Pat<(kind (i32 I64:$addr), (ty V128:$vec), (i32 lane_imm_t:$idx)),
+            (!cast<NI>("STORE_LANE_"#ty#"_A64")
+              0, 0, imm:$idx, I64:$addr, ty:$vec)>,
+        Requires<[HasAddr64]>;
+}
+
+defm : StoreLanePatNoOffset<v16i8, int_wasm_store8_lane, LaneIdx16>;
+defm : StoreLanePatNoOffset<v8i16, int_wasm_store16_lane, LaneIdx8>;
+defm : StoreLanePatNoOffset<v4i32, int_wasm_store32_lane, LaneIdx4>;
+defm : StoreLanePatNoOffset<v2i64, int_wasm_store64_lane, LaneIdx2>;
+
+// TODO: Also support the other store patterns for store_lane once the
+// instructions are merged to the proposal.
+
 //===----------------------------------------------------------------------===//
 // Constructing SIMD values
 //===----------------------------------------------------------------------===//
diff --git a/llvm/test/CodeGen/WebAssembly/simd-load-lane-offset.ll b/llvm/test/CodeGen/WebAssembly/simd-load-lane-offset.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/WebAssembly/simd-load-lane-offset.ll
@@ -0,0 +1,968 @@
+; NOTE: Assertions have been autogenerated by utils/update_llc_test_checks.py
+; RUN: llc < %s -verify-machineinstrs -mattr=+simd128 | FileCheck %s
+
+; Test SIMD v128.load{8,16,32,64}_lane instructions.
+
+; TODO: Use the offset field by supporting more patterns. Right now only the
+; equivalents of LoadPatNoOffset/StorePatNoOffset are supported.
+
+target datalayout = "e-m:e-p:32:32-i64:64-n32:64-S128"
+target triple = "wasm32-unknown-unknown"
+
+declare <16 x i8> @llvm.wasm.load8.lane(i8*, <16 x i8>, i32)
+declare <8 x i16> @llvm.wasm.load16.lane(i16*, <8 x i16>, i32)
+declare <4 x i32> @llvm.wasm.load32.lane(i32*, <4 x i32>, i32)
+declare <2 x i64> @llvm.wasm.load64.lane(i64*, <2 x i64>, i32)
+
+declare void @llvm.wasm.store8.lane(i8*, <16 x i8>, i32)
+declare void @llvm.wasm.store16.lane(i16*, <8 x i16>, i32)
+declare void @llvm.wasm.store32.lane(i32*, <4 x i32>, i32)
+declare void @llvm.wasm.store64.lane(i64*, <2 x i64>, i32)
+
+;===----------------------------------------------------------------------------
+; v128.load8_lane / v128.store8_lane
+;===----------------------------------------------------------------------------
+
+define <16 x i8> @load_lane_i8_no_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_no_offset:
+; CHECK:         .functype load_lane_i8_no_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %p, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_with_folded_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_with_folded_offset:
+; CHECK:         .functype load_lane_i8_with_folded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i8* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i8*
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_with_folded_gep_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_with_folded_gep_offset:
+; CHECK:         .functype load_lane_i8_with_folded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i8, i8* %p, i32 6
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_with_unfolded_gep_negative_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_with_unfolded_gep_negative_offset:
+; CHECK:         .functype load_lane_i8_with_unfolded_gep_negative_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const -6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i8, i8* %p, i32 -6
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_with_unfolded_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_with_unfolded_offset:
+; CHECK:         .functype load_lane_i8_with_unfolded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i8* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i8*
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_with_unfolded_gep_offset(i8* %p, <16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_with_unfolded_gep_offset:
+; CHECK:         .functype load_lane_i8_with_unfolded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i8, i8* %p, i32 6
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define <16 x i8> @load_lane_i8_from_numeric_address(<16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_from_numeric_address:
+; CHECK:         .functype load_lane_i8_from_numeric_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i8*
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+@gv_i8 = global i8 0
+define <16 x i8> @load_lane_i8_from_global_address(<16 x i8> %v) {
+; CHECK-LABEL: load_lane_i8_from_global_address:
+; CHECK:         .functype load_lane_i8_from_global_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i8
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <16 x i8> @llvm.wasm.load8.lane(i8* @gv_i8, <16 x i8> %v, i32 0)
+  ret <16 x i8> %t
+}
+
+define void @store_lane_i8_no_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_no_offset:
+; CHECK:         .functype store_lane_i8_no_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store8.lane(i8* %p, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_with_folded_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_with_folded_offset:
+; CHECK:         .functype store_lane_i8_with_folded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i8* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i8*
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_with_folded_gep_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_with_folded_gep_offset:
+; CHECK:         .functype store_lane_i8_with_folded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i8, i8* %p, i32 6
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_with_unfolded_gep_negative_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_with_unfolded_gep_negative_offset:
+; CHECK:         .functype store_lane_i8_with_unfolded_gep_negative_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const -6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i8, i8* %p, i32 -6
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_with_unfolded_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_with_unfolded_offset:
+; CHECK:         .functype store_lane_i8_with_unfolded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i8* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i8*
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_with_unfolded_gep_offset(<16 x i8> %v, i8* %p) {
+; CHECK-LABEL: store_lane_i8_with_unfolded_gep_offset:
+; CHECK:         .functype store_lane_i8_with_unfolded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 6
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i8, i8* %p, i32 6
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_to_numeric_address(<16 x i8> %v) {
+; CHECK-LABEL: store_lane_i8_to_numeric_address:
+; CHECK:         .functype store_lane_i8_to_numeric_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i8*
+  tail call void @llvm.wasm.store8.lane(i8* %s, <16 x i8> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i8_from_global_address(<16 x i8> %v) {
+; CHECK-LABEL: store_lane_i8_from_global_address:
+; CHECK:         .functype store_lane_i8_from_global_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i8
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store8_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store8.lane(i8* @gv_i8, <16 x i8> %v, i32 0)
+  ret void
+}
+
+;===----------------------------------------------------------------------------
+; v128.load16_lane / v128.store16_lane
+;===----------------------------------------------------------------------------
+
+define <8 x i16> @load_lane_i16_no_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_no_offset:
+; CHECK:         .functype load_lane_i16_no_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %p, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_with_folded_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_with_folded_offset:
+; CHECK:         .functype load_lane_i16_with_folded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i16* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i16*
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_with_folded_gep_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_with_folded_gep_offset:
+; CHECK:         .functype load_lane_i16_with_folded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i16, i16* %p, i32 6
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_with_unfolded_gep_negative_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_with_unfolded_gep_negative_offset:
+; CHECK:         .functype load_lane_i16_with_unfolded_gep_negative_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const -12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i16, i16* %p, i32 -6
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_with_unfolded_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_with_unfolded_offset:
+; CHECK:         .functype load_lane_i16_with_unfolded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i16* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i16*
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_with_unfolded_gep_offset(i16* %p, <8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_with_unfolded_gep_offset:
+; CHECK:         .functype load_lane_i16_with_unfolded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i16, i16* %p, i32 6
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define <8 x i16> @load_lane_i16_from_numeric_address(<8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_from_numeric_address:
+; CHECK:         .functype load_lane_i16_from_numeric_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i16*
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+@gv_i16 = global i16 0
+define <8 x i16> @load_lane_i16_from_global_address(<8 x i16> %v) {
+; CHECK-LABEL: load_lane_i16_from_global_address:
+; CHECK:         .functype load_lane_i16_from_global_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i16
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <8 x i16> @llvm.wasm.load16.lane(i16* @gv_i16, <8 x i16> %v, i32 0)
+  ret <8 x i16> %t
+}
+
+define void @store_lane_i16_no_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_no_offset:
+; CHECK:         .functype store_lane_i16_no_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store16.lane(i16* %p, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_with_folded_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_with_folded_offset:
+; CHECK:         .functype store_lane_i16_with_folded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i16* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i16*
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_with_folded_gep_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_with_folded_gep_offset:
+; CHECK:         .functype store_lane_i16_with_folded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i16, i16* %p, i32 6
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_with_unfolded_gep_negative_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_with_unfolded_gep_negative_offset:
+; CHECK:         .functype store_lane_i16_with_unfolded_gep_negative_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const -12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i16, i16* %p, i32 -6
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_with_unfolded_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_with_unfolded_offset:
+; CHECK:         .functype store_lane_i16_with_unfolded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i16* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i16*
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_with_unfolded_gep_offset(<8 x i16> %v, i16* %p) {
+; CHECK-LABEL: store_lane_i16_with_unfolded_gep_offset:
+; CHECK:         .functype store_lane_i16_with_unfolded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 12
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i16, i16* %p, i32 6
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_to_numeric_address(<8 x i16> %v) {
+; CHECK-LABEL: store_lane_i16_to_numeric_address:
+; CHECK:         .functype store_lane_i16_to_numeric_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i16*
+  tail call void @llvm.wasm.store16.lane(i16* %s, <8 x i16> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i16_from_global_address(<8 x i16> %v) {
+; CHECK-LABEL: store_lane_i16_from_global_address:
+; CHECK:         .functype store_lane_i16_from_global_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i16
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store16_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store16.lane(i16* @gv_i16, <8 x i16> %v, i32 0)
+  ret void
+}
+
+;===----------------------------------------------------------------------------
+; v128.load32_lane / v128.store32_lane
+;===----------------------------------------------------------------------------
+
+define <4 x i32> @load_lane_i32_no_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_no_offset:
+; CHECK:         .functype load_lane_i32_no_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %p, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_with_folded_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_with_folded_offset:
+; CHECK:         .functype load_lane_i32_with_folded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i32* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i32*
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_with_folded_gep_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_with_folded_gep_offset:
+; CHECK:         .functype load_lane_i32_with_folded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i32, i32* %p, i32 6
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_with_unfolded_gep_negative_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_with_unfolded_gep_negative_offset:
+; CHECK:         .functype load_lane_i32_with_unfolded_gep_negative_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const -24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i32, i32* %p, i32 -6
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_with_unfolded_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_with_unfolded_offset:
+; CHECK:         .functype load_lane_i32_with_unfolded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i32* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i32*
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_with_unfolded_gep_offset(i32* %p, <4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_with_unfolded_gep_offset:
+; CHECK:         .functype load_lane_i32_with_unfolded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i32, i32* %p, i32 6
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define <4 x i32> @load_lane_i32_from_numeric_address(<4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_from_numeric_address:
+; CHECK:         .functype load_lane_i32_from_numeric_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i32*
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+@gv_i32 = global i32 0
+define <4 x i32> @load_lane_i32_from_global_address(<4 x i32> %v) {
+; CHECK-LABEL: load_lane_i32_from_global_address:
+; CHECK:         .functype load_lane_i32_from_global_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i32
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <4 x i32> @llvm.wasm.load32.lane(i32* @gv_i32, <4 x i32> %v, i32 0)
+  ret <4 x i32> %t
+}
+
+define void @store_lane_i32_no_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_no_offset:
+; CHECK:         .functype store_lane_i32_no_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store32.lane(i32* %p, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_with_folded_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_with_folded_offset:
+; CHECK:         .functype store_lane_i32_with_folded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i32* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i32*
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_with_folded_gep_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_with_folded_gep_offset:
+; CHECK:         .functype store_lane_i32_with_folded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i32, i32* %p, i32 6
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_with_unfolded_gep_negative_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_with_unfolded_gep_negative_offset:
+; CHECK:         .functype store_lane_i32_with_unfolded_gep_negative_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const -24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i32, i32* %p, i32 -6
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_with_unfolded_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_with_unfolded_offset:
+; CHECK:         .functype store_lane_i32_with_unfolded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i32* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i32*
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_with_unfolded_gep_offset(<4 x i32> %v, i32* %p) {
+; CHECK-LABEL: store_lane_i32_with_unfolded_gep_offset:
+; CHECK:         .functype store_lane_i32_with_unfolded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i32, i32* %p, i32 6
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_to_numeric_address(<4 x i32> %v) {
+; CHECK-LABEL: store_lane_i32_to_numeric_address:
+; CHECK:         .functype store_lane_i32_to_numeric_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i32*
+  tail call void @llvm.wasm.store32.lane(i32* %s, <4 x i32> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i32_from_global_address(<4 x i32> %v) {
+; CHECK-LABEL: store_lane_i32_from_global_address:
+; CHECK:         .functype store_lane_i32_from_global_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i32
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store32_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store32.lane(i32* @gv_i32, <4 x i32> %v, i32 0)
+  ret void
+}
+
+;===----------------------------------------------------------------------------
+; v128.load64_lane / v128.store64_lane
+;===----------------------------------------------------------------------------
+
+define <2 x i64> @load_lane_i64_no_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_no_offset:
+; CHECK:         .functype load_lane_i64_no_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %p, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_with_folded_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_with_folded_offset:
+; CHECK:         .functype load_lane_i64_with_folded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i64* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i64*
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_with_folded_gep_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_with_folded_gep_offset:
+; CHECK:         .functype load_lane_i64_with_folded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i64, i64* %p, i32 6
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_with_unfolded_gep_negative_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_with_unfolded_gep_negative_offset:
+; CHECK:         .functype load_lane_i64_with_unfolded_gep_negative_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const -48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i64, i64* %p, i32 -6
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_with_unfolded_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_with_unfolded_offset:
+; CHECK:         .functype load_lane_i64_with_unfolded_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i64* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i64*
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_with_unfolded_gep_offset(i64* %p, <2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_with_unfolded_gep_offset:
+; CHECK:         .functype load_lane_i64_with_unfolded_gep_offset (i32, v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    i32.const 48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i64, i64* %p, i32 6
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define <2 x i64> @load_lane_i64_from_numeric_address(<2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_from_numeric_address:
+; CHECK:         .functype load_lane_i64_from_numeric_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i64*
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+@gv_i64 = global i64 0
+define <2 x i64> @load_lane_i64_from_global_address(<2 x i64> %v) {
+; CHECK-LABEL: load_lane_i64_from_global_address:
+; CHECK:         .functype load_lane_i64_from_global_address (v128) -> (v128)
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i64
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.load64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %t = tail call <2 x i64> @llvm.wasm.load64.lane(i64* @gv_i64, <2 x i64> %v, i32 0)
+  ret <2 x i64> %t
+}
+
+define void @store_lane_i64_no_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_no_offset:
+; CHECK:         .functype store_lane_i64_no_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store64.lane(i64* %p, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_with_folded_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_with_folded_offset:
+; CHECK:         .functype store_lane_i64_with_folded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i64* %p to i32
+  %r = add nuw i32 %q, 24
+  %s = inttoptr i32 %r to i64*
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_with_folded_gep_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_with_folded_gep_offset:
+; CHECK:         .functype store_lane_i64_with_folded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i64, i64* %p, i32 6
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_with_unfolded_gep_negative_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_with_unfolded_gep_negative_offset:
+; CHECK:         .functype store_lane_i64_with_unfolded_gep_negative_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const -48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr inbounds i64, i64* %p, i32 -6
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_with_unfolded_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_with_unfolded_offset:
+; CHECK:         .functype store_lane_i64_with_unfolded_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 24
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %q = ptrtoint i64* %p to i32
+  %r = add nsw i32 %q, 24
+  %s = inttoptr i32 %r to i64*
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_with_unfolded_gep_offset(<2 x i64> %v, i64* %p) {
+; CHECK-LABEL: store_lane_i64_with_unfolded_gep_offset:
+; CHECK:         .functype store_lane_i64_with_unfolded_gep_offset (v128, i32) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    local.get 1
+; CHECK-NEXT:    i32.const 48
+; CHECK-NEXT:    i32.add
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = getelementptr i64, i64* %p, i32 6
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_to_numeric_address(<2 x i64> %v) {
+; CHECK-LABEL: store_lane_i64_to_numeric_address:
+; CHECK:         .functype store_lane_i64_to_numeric_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const 42
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  %s = inttoptr i32 42 to i64*
+  tail call void @llvm.wasm.store64.lane(i64* %s, <2 x i64> %v, i32 0)
+  ret void
+}
+
+define void @store_lane_i64_from_global_address(<2 x i64> %v) {
+; CHECK-LABEL: store_lane_i64_from_global_address:
+; CHECK:         .functype store_lane_i64_from_global_address (v128) -> ()
+; CHECK-NEXT:  # %bb.0:
+; CHECK-NEXT:    i32.const gv_i64
+; CHECK-NEXT:    local.get 0
+; CHECK-NEXT:    v128.store64_lane 0, 0
+; CHECK-NEXT:    # fallthrough-return
+  tail call void @llvm.wasm.store64.lane(i64* @gv_i64, <2 x i64> %v, i32 0)
+  ret void
+}
diff --git a/llvm/test/MC/WebAssembly/simd-encodings.s b/llvm/test/MC/WebAssembly/simd-encodings.s
--- a/llvm/test/MC/WebAssembly/simd-encodings.s
+++ b/llvm/test/MC/WebAssembly/simd-encodings.s
@@ -280,6 +280,30 @@
     # CHECK: v128.bitselect # encoding: [0xfd,0x52]
     v128.bitselect
 
+    # CHECK: v128.load8_lane 32, 1 # encoding: [0xfd,0x58,0x00,0x20,0x01]
+    v128.load8_lane 32, 1
+
+    # CHECK: v128.load16_lane 32, 1 # encoding: [0xfd,0x59,0x01,0x20,0x01]
+    v128.load16_lane 32, 1
+
+    # CHECK: v128.load32_lane 32, 1 # encoding: [0xfd,0x5a,0x02,0x20,0x01]
+    v128.load32_lane 32, 1
+
+    # CHECK: v128.load64_lane 32, 1 # encoding: [0xfd,0x5b,0x03,0x20,0x01]
+    v128.load64_lane 32, 1
+
+    # CHECK: v128.store8_lane 32, 1 # encoding: [0xfd,0x5c,0x00,0x20,0x01]
+    v128.store8_lane 32, 1
+
+    # CHECK: v128.store16_lane 32, 1 # encoding: [0xfd,0x5d,0x01,0x20,0x01]
+    v128.store16_lane 32, 1
+
+    # CHECK: v128.store32_lane 32, 1 # encoding: [0xfd,0x5e,0x02,0x20,0x01]
+    v128.store32_lane 32, 1
+
+    # CHECK: v128.store64_lane 32, 1 # encoding: [0xfd,0x5f,0x03,0x20,0x01]
+    v128.store64_lane 32, 1
+
     # CHECK: i8x16.abs # encoding: [0xfd,0x60]
     i8x16.abs