diff --git a/clang/lib/CodeGen/CGBuiltin.cpp b/clang/lib/CodeGen/CGBuiltin.cpp
--- a/clang/lib/CodeGen/CGBuiltin.cpp
+++ b/clang/lib/CodeGen/CGBuiltin.cpp
@@ -808,7 +808,12 @@
   AsmOS << SizeSuffix << " $2, ($1)\n\tsetc ${0:b}";
 
   // Build the constraints. FIXME: We should support immediates when possible.
-  std::string Constraints = "=r,r,r,~{cc},~{flags},~{fpsr}";
+  std::string Constraints = "=r,r,r,~{cc},~{memory}";
+  std::string MachineClobbers = CGF.getTarget().getClobbers();
+  if (!MachineClobbers.empty()) {
+    Constraints += ',';
+    Constraints += MachineClobbers;
+  }
   llvm::IntegerType *IntType = llvm::IntegerType::get(
       CGF.getLLVMContext(),
       CGF.getContext().getTypeSize(E->getArg(1)->getType()));
diff --git a/clang/test/CodeGen/bittest-intrin.c b/clang/test/CodeGen/bittest-intrin.c
--- a/clang/test/CodeGen/bittest-intrin.c
+++ b/clang/test/CodeGen/bittest-intrin.c
@@ -34,20 +34,20 @@
 #endif
 
 // X64-LABEL: define dso_local void @test32(i32* %base, i32 %idx)
-// X64: call i8 asm sideeffect "btl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
-// X64: call i8 asm sideeffect "btcl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
-// X64: call i8 asm sideeffect "btrl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
-// X64: call i8 asm sideeffect "btsl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
-// X64: call i8 asm sideeffect "lock btrl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
-// X64: call i8 asm sideeffect "lock btsl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "btl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "btcl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "btrl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "btsl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "lock btrl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
+// X64: call i8 asm sideeffect "lock btsl $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i32* %{{.*}}, i32 {{.*}})
 
 // X64-LABEL: define dso_local void @test64(i64* %base, i64 %idx)
-// X64: call i8 asm sideeffect "btq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
-// X64: call i8 asm sideeffect "btcq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
-// X64: call i8 asm sideeffect "btrq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
-// X64: call i8 asm sideeffect "btsq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
-// X64: call i8 asm sideeffect "lock btrq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
-// X64: call i8 asm sideeffect "lock btsq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{{.*}}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "btq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "btcq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "btrq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "btsq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "lock btrq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
+// X64: call i8 asm sideeffect "lock btsq $2, ($1)\0A\09setc ${0:b}", "=r,r,r,~{cc},~{memory},~{dirflag},~{fpsr},~{flags}"(i64* %{{.*}}, i64 {{.*}})
 
 // ARM-LABEL: define dso_local {{.*}}void @test32(i32* %base, i32 %idx)
 // ARM: %[[IDXHI:[^ ]*]] = ashr i32 %{{.*}}, 3