diff --git a/clang/lib/Driver/ToolChains/Gnu.h b/clang/lib/Driver/ToolChains/Gnu.h
--- a/clang/lib/Driver/ToolChains/Gnu.h
+++ b/clang/lib/Driver/ToolChains/Gnu.h
@@ -212,6 +212,9 @@
     /// The set of multilibs that the detected installation supports.
     MultilibSet Multilibs;
 
+    // Gentoo-specific toolchain configurations are stored here.
+    const std::string GentooConfigDir = "/etc/env.d/gcc";
+
   public:
     explicit GCCInstallationDetector(const Driver &D) : IsValid(false), D(D) {}
     void init(const llvm::Triple &TargetTriple, const llvm::opt::ArgList &Args,
diff --git a/clang/lib/Driver/ToolChains/Gnu.cpp b/clang/lib/Driver/ToolChains/Gnu.cpp
--- a/clang/lib/Driver/ToolChains/Gnu.cpp
+++ b/clang/lib/Driver/ToolChains/Gnu.cpp
@@ -2535,6 +2535,9 @@
     const llvm::Triple &TargetTriple, const ArgList &Args,
     const SmallVectorImpl<StringRef> &CandidateTriples,
     const SmallVectorImpl<StringRef> &CandidateBiarchTriples) {
+  if (!D.getVFS().exists(D.SysRoot + GentooConfigDir))
+    return false;
+
   for (StringRef CandidateTriple : CandidateTriples) {
     if (ScanGentooGccConfig(TargetTriple, Args, CandidateTriple))
       return true;
@@ -2551,7 +2554,7 @@
     const llvm::Triple &TargetTriple, const ArgList &Args,
     StringRef CandidateTriple, bool NeedsBiarchSuffix) {
   llvm::ErrorOr<std::unique_ptr<llvm::MemoryBuffer>> File =
-      D.getVFS().getBufferForFile(D.SysRoot + "/etc/env.d/gcc/config-" +
+      D.getVFS().getBufferForFile(D.SysRoot + GentooConfigDir + "/config-" +
                                   CandidateTriple.str());
   if (File) {
     SmallVector<StringRef, 2> Lines;
@@ -2563,7 +2566,7 @@
         continue;
       // Process the config file pointed to by CURRENT.
       llvm::ErrorOr<std::unique_ptr<llvm::MemoryBuffer>> ConfigFile =
-          D.getVFS().getBufferForFile(D.SysRoot + "/etc/env.d/gcc/" +
+          D.getVFS().getBufferForFile(D.SysRoot + GentooConfigDir + "/" +
                                       Line.str());
       std::pair<StringRef, StringRef> ActiveVersion = Line.rsplit('-');
       // List of paths to scan for libraries.