diff --git a/lldb/bindings/python/CMakeLists.txt b/lldb/bindings/python/CMakeLists.txt
--- a/lldb/bindings/python/CMakeLists.txt
+++ b/lldb/bindings/python/CMakeLists.txt
@@ -165,16 +165,19 @@
   endif()
   set(python_scripts_target "lldb-python-scripts")
   set(python_scripts_install_target "install-${python_scripts_target}")
-  add_custom_target(${python_scripts_target})
+  # This function might be called multiple times but we only need to create the custom target once.
+  if (NOT TARGET ${python_scripts_target})
+    add_custom_target(${python_scripts_target})
+    if (NOT LLVM_ENABLE_IDE)
+      add_llvm_install_targets(${python_scripts_install_target}
+                              COMPONENT ${python_scripts_target}
+                              DEPENDS ${python_scripts_target})
+    endif()
+  endif()
   add_dependencies(${python_scripts_target} ${swig_target})
   install(DIRECTORY ${lldb_python_target_dir}/../
           DESTINATION ${LLDB_PYTHON_INSTALL_PATH}
           COMPONENT ${python_scripts_target})
-  if (NOT LLVM_ENABLE_IDE)
-    add_llvm_install_targets(${python_scripts_install_target}
-                             COMPONENT ${python_scripts_target}
-                             DEPENDS ${python_scripts_target})
-  endif()
 
   # Add a Post-Build Event to copy the custom Python DLL to the lldb binaries dir so that Windows can find it when launching
   # lldb.exe or any other executables that were linked with liblldb.