diff --git a/compiler-rt/lib/profile/CMakeLists.txt b/compiler-rt/lib/profile/CMakeLists.txt
--- a/compiler-rt/lib/profile/CMakeLists.txt
+++ b/compiler-rt/lib/profile/CMakeLists.txt
@@ -113,6 +113,8 @@
 
 # We don't use the C++ Standard Library here, so avoid including it by mistake.
 append_list_if(COMPILER_RT_HAS_NOSTDINCXX_FLAG -nostdinc++ EXTRA_FLAGS)
+# Remove -stdlib= which is unused when passing -nostdinc++.
+string(REGEX REPLACE "-stdlib=[a-zA-Z+]*" "" CMAKE_CXX_FLAGS ${CMAKE_CXX_FLAGS})
 
 # This appears to be a C-only warning banning the use of locals in aggregate
 # initializers. All other compilers accept this, though.