Index: lib/Sema/SemaStmtAsm.cpp
===================================================================
--- lib/Sema/SemaStmtAsm.cpp
+++ lib/Sema/SemaStmtAsm.cpp
@@ -124,6 +124,19 @@
   // The parser verifies that there is a string literal here.
   assert(AsmString->isAscii());
 
+  bool ValidateConstraints;
+  if (getLangOpts().CUDA) {
+    // In CUDA mode don't verify asm constraints in device functions during host
+    // compilation and vice versa.
+    bool InDeviceMode = getLangOpts().CUDAIsDevice;
+    FunctionDecl *FD = getCurFunctionDecl();
+    bool IsDeviceFunction =
+        FD && (FD->hasAttr<CUDADeviceAttr>() || FD->hasAttr<CUDAGlobalAttr>());
+    ValidateConstraints = IsDeviceFunction == InDeviceMode;
+  } else {
+    ValidateConstraints = true;
+  }
+
   for (unsigned i = 0; i != NumOutputs; i++) {
     StringLiteral *Literal = Constraints[i];
     assert(Literal->isAscii());
@@ -133,7 +146,8 @@
       OutputName = Names[i]->getName();
 
     TargetInfo::ConstraintInfo Info(Literal->getString(), OutputName);
-    if (!Context.getTargetInfo().validateOutputConstraint(Info))
+    if (ValidateConstraints &&
+        !Context.getTargetInfo().validateOutputConstraint(Info))
       return StmtError(Diag(Literal->getLocStart(),
                             diag::err_asm_invalid_output_constraint)
                        << Info.getConstraintStr());
@@ -207,8 +221,9 @@
       InputName = Names[i]->getName();
 
     TargetInfo::ConstraintInfo Info(Literal->getString(), InputName);
-    if (!Context.getTargetInfo().validateInputConstraint(OutputConstraintInfos.data(),
-                                                NumOutputs, Info)) {
+    if (ValidateConstraints &&
+        !Context.getTargetInfo().validateInputConstraint(
+            OutputConstraintInfos.data(), NumOutputs, Info)) {
       return StmtError(Diag(Literal->getLocStart(),
                             diag::err_asm_invalid_input_constraint)
                        << Info.getConstraintStr());
Index: test/SemaCUDA/asm-constraints.cu
===================================================================
--- /dev/null
+++ test/SemaCUDA/asm-constraints.cu
@@ -0,0 +1,15 @@
+// RUN: %clang_cc1 -triple nvptx-unknown-cuda -fsyntax-only -fcuda-is-device -verify %s
+// RUN: %clang_cc1 -triple x86_64-unknown-linux-gnu -fsyntax-only -verify %s
+// expected-no-diagnostics
+
+__attribute__((device)) void df() {
+  short h;
+  // asm with PTX constraints. Some of them are PTX-specific.
+  __asm__("dont care" : "=h"(h): "f"(0.0), "d"(0.0), "h"(0), "r"(0), "l"(0));
+}
+
+void hf() {
+  int a;
+  // Asm with x86 constraints that are not supported by PTX.
+  __asm__("dont care" : "=a"(a): "a"(0), "b"(0), "c"(0));
+}