Index: lib/Analysis/ScalarEvolutionExpander.cpp
===================================================================
--- lib/Analysis/ScalarEvolutionExpander.cpp
+++ lib/Analysis/ScalarEvolutionExpander.cpp
@@ -1771,9 +1771,13 @@
                         << *IsomorphicInc << '\n');
         Value *NewInc = OrigInc;
         if (OrigInc->getType() != IsomorphicInc->getType()) {
-          Instruction *IP = isa<PHINode>(OrigInc)
-            ? (Instruction*)L->getHeader()->getFirstInsertionPt()
-            : OrigInc->getNextNode();
+          Instruction *IP = [OrigInc]() {
+            if (PHINode *PN = dyn_cast<PHINode>(OrigInc))
+              return &*PN->getParent()->getFirstInsertionPt();
+            else
+              return OrigInc->getNextNode();
+          }();
+
           IRBuilder<> Builder(IP);
           Builder.SetCurrentDebugLocation(IsomorphicInc->getDebugLoc());
           NewInc = Builder.
Index: test/Analysis/ScalarEvolution/pr22856.ll
===================================================================
--- /dev/null
+++ test/Analysis/ScalarEvolution/pr22856.ll
@@ -0,0 +1,33 @@
+; RUN: opt -loop-reduce -verify < %s
+
+target datalayout = "e-m:e-i64:64-f80:128-n8:16:32:64-S128"
+target triple = "x86_64--linux-gnu"
+
+define void @unbounded() {
+
+block_A:
+  %0 = sext i32 undef to i64
+  br i1 undef, label %block_F, label %block_G
+
+block_C:                ; preds = %block_F
+  br i1 undef, label %block_D, label %block_E
+
+block_D:                  ; preds = %block_D, %block_C
+  br i1 undef, label %block_E, label %block_D
+
+block_E:              ; preds = %block_D, %block_C
+  %iv2 = phi i64 [ %4, %block_D ], [ %4, %block_C ]
+  %1 = add nsw i32 %iv1, 1
+  %2 = icmp eq i32 %1, undef
+  br i1 %2, label %block_G, label %block_F
+
+block_F:          ; preds = %block_E, %block_A
+  %iv3 = phi i64 [ %iv2, %block_E ], [ %0, %block_A ]
+  %iv1 = phi i32 [ %1, %block_E ], [ undef, %block_A ]
+  %3 = add nsw i64 %iv3, 2
+  %4 = add nsw i64 %iv3, 1
+  br label %block_C
+
+block_G:                              ; preds = %block_E, %block_A
+  ret void
+}