diff --git a/llvm/lib/Target/X86/X86LoadValueInjectionRetHardening.cpp b/llvm/lib/Target/X86/X86LoadValueInjectionRetHardening.cpp
--- a/llvm/lib/Target/X86/X86LoadValueInjectionRetHardening.cpp
+++ b/llvm/lib/Target/X86/X86LoadValueInjectionRetHardening.cpp
@@ -99,6 +99,9 @@
 
   bool Modified = false;
   for (auto &MBB : MF) {
+    if (MBB.empty())
+      continue;
+
     MachineInstr &MI = MBB.back();
     if (MI.getOpcode() != X86::RETQ)
       continue;