diff --git a/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h b/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
--- a/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
+++ b/llvm/include/llvm/CodeGen/GlobalISel/LegalizationArtifactCombiner.h
@@ -250,6 +250,22 @@
       return true;
     }
 
+    // trunc(trunc) -> trunc
+    Register TruncSrc;
+    if (mi_match(SrcReg, MRI, m_GTrunc(m_Reg(TruncSrc)))) {
+      const LLT DstTy = MRI.getType(DstReg);
+      const LLT TruncSrcTy = MRI.getType(TruncSrc);
+      if (!isInstLegal({TargetOpcode::G_TRUNC, {DstTy, TruncSrcTy}}))
+        return false;
+
+      LLVM_DEBUG(dbgs() << ".. Combine G_TRUNC(G_TRUNC): " << MI);
+
+      Builder.buildTrunc(DstReg, TruncSrc);
+      UpdatedDefs.push_back(DstReg);
+      markInstAndDefDead(MI, *MRI.getVRegDef(TruncSrc), DeadInsts);
+      return true;
+    }
+
     return false;
   }
 
diff --git a/llvm/test/CodeGen/AArch64/GlobalISel/legalize-load-trunc.mir b/llvm/test/CodeGen/AArch64/GlobalISel/legalize-load-trunc.mir
--- a/llvm/test/CodeGen/AArch64/GlobalISel/legalize-load-trunc.mir
+++ b/llvm/test/CodeGen/AArch64/GlobalISel/legalize-load-trunc.mir
@@ -12,9 +12,8 @@
     ; CHECK-LABEL: name: test_load_trunc
     ; CHECK: [[FRAME_INDEX:%[0-9]+]]:_(p0) = G_FRAME_INDEX %stack.0
     ; CHECK: [[LOAD:%[0-9]+]]:_(s16) = G_LOAD [[FRAME_INDEX]](p0) :: (load 2)
-    ; CHECK: [[TRUNC:%[0-9]+]]:_(s10) = G_TRUNC [[LOAD]](s16)
-    ; CHECK: [[TRUNC1:%[0-9]+]]:_(s1) = G_TRUNC [[TRUNC]](s10)
-    ; CHECK: RET_ReallyLR implicit [[TRUNC1]](s1)
+    ; CHECK: [[TRUNC:%[0-9]+]]:_(s1) = G_TRUNC [[LOAD]](s16)
+    ; CHECK: RET_ReallyLR implicit [[TRUNC]](s1)
     %0:_(p0) = G_FRAME_INDEX %stack.0
     %1:_(s10) = G_LOAD %0(p0) :: (load 2)
     %2:_(s1) = G_TRUNC %1(s10)
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/artifact-combiner-trunc.mir
@@ -118,15 +118,13 @@
 
 body: |
   bb.0:
-    ; Test that trunc(merge) with trunc-size > merge-source-size is not combined
-    ; if trunc-size % merge-source-size != 0
+    ; Test that trunc(merge) with trunc-size > merge-source-size and
+    ; trunc-size % merge-source-size != 0 can be combined after the G_TRUNCs
+    ; have been combined.
     ; CHECK-LABEL: name: trunc_s68_merge_s128_s32
     ; CHECK: [[C:%[0-9]+]]:_(s32) = G_CONSTANT i32 0
     ; CHECK: [[C1:%[0-9]+]]:_(s32) = G_CONSTANT i32 1
-    ; CHECK: [[MV:%[0-9]+]]:_(s128) = G_MERGE_VALUES [[C]](s32), [[C1]](s32), [[C]](s32), [[C1]](s32)
-    ; CHECK: [[TRUNC:%[0-9]+]]:_(s68) = G_TRUNC [[MV]](s128)
-    ; CHECK: [[TRUNC1:%[0-9]+]]:_(s32) = G_TRUNC [[TRUNC]](s68)
-    ; CHECK: $vgpr0 = COPY [[TRUNC1]](s32)
+    ; CHECK: $vgpr0 = COPY [[C]](s32)
     %0:_(s32) = G_CONSTANT i32 0
     %1:_(s32) = G_CONSTANT i32 1
     %2:_(s128) = G_MERGE_VALUES %0, %1, %0, %1
@@ -134,3 +132,19 @@
     %4:_(s32) = G_TRUNC %3
     $vgpr0 = COPY %4
 ...
+
+---
+name: trunc_trunc
+
+body: |
+  bb.0:
+    ; Test that trunc(trunc) is combined to a single trunc
+    ; CHECK-LABEL: name: trunc_trunc
+    ; CHECK: [[DEF:%[0-9]+]]:_(s64) = G_IMPLICIT_DEF
+    ; CHECK: [[TRUNC:%[0-9]+]]:_(s32) = G_TRUNC [[DEF]](s64)
+    ; CHECK: $vgpr0 = COPY [[TRUNC]](s32)
+    %0:_(s64) = G_IMPLICIT_DEF
+    %1:_(s48) = G_TRUNC %0
+    %2:_(s32) = G_TRUNC %1
+    $vgpr0 = COPY %2
+...
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-bitcast.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-bitcast.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-bitcast.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-bitcast.mir
@@ -340,8 +340,7 @@
     ; CHECK: [[SHL:%[0-9]+]]:_(s32) = G_SHL [[AND1]], [[C]](s32)
     ; CHECK: [[OR:%[0-9]+]]:_(s32) = G_OR [[AND]], [[SHL]]
     ; CHECK: [[BITCAST:%[0-9]+]]:_(<2 x s16>) = G_BITCAST [[OR]](s32)
-    ; CHECK: [[COPY4:%[0-9]+]]:_(s32) = COPY [[TRUNC]](s32)
-    ; CHECK: [[AND2:%[0-9]+]]:_(s32) = G_AND [[COPY4]], [[C1]]
+    ; CHECK: [[AND2:%[0-9]+]]:_(s32) = G_AND [[TRUNC]], [[C1]]
     ; CHECK: [[C2:%[0-9]+]]:_(s32) = G_CONSTANT i32 0
     ; CHECK: [[SHL1:%[0-9]+]]:_(s32) = G_SHL [[C2]], [[C]](s32)
     ; CHECK: [[OR1:%[0-9]+]]:_(s32) = G_OR [[AND2]], [[SHL1]]
@@ -355,10 +354,10 @@
     ; CHECK: [[LSHR2:%[0-9]+]]:_(s32) = G_LSHR [[BITCAST2]], [[C]](s32)
     ; CHECK: [[BITCAST3:%[0-9]+]]:_(s32) = G_BITCAST [[UV3]](<2 x s16>)
     ; CHECK: [[LSHR3:%[0-9]+]]:_(s32) = G_LSHR [[BITCAST3]], [[C]](s32)
-    ; CHECK: [[COPY5:%[0-9]+]]:_(s32) = COPY [[BITCAST2]](s32)
-    ; CHECK: [[COPY6:%[0-9]+]]:_(s32) = COPY [[LSHR2]](s32)
-    ; CHECK: [[COPY7:%[0-9]+]]:_(s32) = COPY [[BITCAST3]](s32)
-    ; CHECK: [[BUILD_VECTOR:%[0-9]+]]:_(<3 x s32>) = G_BUILD_VECTOR [[COPY5]](s32), [[COPY6]](s32), [[COPY7]](s32)
+    ; CHECK: [[COPY4:%[0-9]+]]:_(s32) = COPY [[BITCAST2]](s32)
+    ; CHECK: [[COPY5:%[0-9]+]]:_(s32) = COPY [[LSHR2]](s32)
+    ; CHECK: [[COPY6:%[0-9]+]]:_(s32) = COPY [[BITCAST3]](s32)
+    ; CHECK: [[BUILD_VECTOR:%[0-9]+]]:_(<3 x s32>) = G_BUILD_VECTOR [[COPY4]](s32), [[COPY5]](s32), [[COPY6]](s32)
     ; CHECK: $vgpr0_vgpr1_vgpr2 = COPY [[BUILD_VECTOR]](<3 x s32>)
     %0:_(s64) = COPY $vgpr0_vgpr1
     %1:_(s48) = G_TRUNC %0
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-extract.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-extract.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-extract.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-extract.mir
@@ -56,8 +56,7 @@
     ; CHECK-LABEL: name: test_extract_s16_s31_offset0
     ; CHECK: [[COPY:%[0-9]+]]:_(s64) = COPY $vgpr0_vgpr1
     ; CHECK: [[TRUNC:%[0-9]+]]:_(s32) = G_TRUNC [[COPY]](s64)
-    ; CHECK: [[COPY1:%[0-9]+]]:_(s32) = COPY [[TRUNC]](s32)
-    ; CHECK: $vgpr0 = COPY [[COPY1]](s32)
+    ; CHECK: $vgpr0 = COPY [[TRUNC]](s32)
     %0:_(s64) = COPY $vgpr0_vgpr1
     %1:_(s31) = G_TRUNC %0
     %2:_(s16) = G_EXTRACT %1, 0
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-inttoptr.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-inttoptr.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-inttoptr.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-inttoptr.mir
@@ -188,9 +188,8 @@
 
     ; CHECK-LABEL: name: test_inttoptr_s33_to_p3
     ; CHECK: [[COPY:%[0-9]+]]:_(s64) = COPY $vgpr0_vgpr1
-    ; CHECK: [[TRUNC:%[0-9]+]]:_(s33) = G_TRUNC [[COPY]](s64)
-    ; CHECK: [[TRUNC1:%[0-9]+]]:_(s32) = G_TRUNC [[TRUNC]](s33)
-    ; CHECK: [[INTTOPTR:%[0-9]+]]:_(p3) = G_INTTOPTR [[TRUNC1]](s32)
+    ; CHECK: [[TRUNC:%[0-9]+]]:_(s32) = G_TRUNC [[COPY]](s64)
+    ; CHECK: [[INTTOPTR:%[0-9]+]]:_(p3) = G_INTTOPTR [[TRUNC]](s32)
     ; CHECK: S_ENDPGM 0, implicit [[INTTOPTR]](p3)
     %0:_(s64) = COPY $vgpr0_vgpr1
     %1:_(s33) = G_TRUNC %0
diff --git a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-trunc.mir b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-trunc.mir
--- a/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-trunc.mir
+++ b/llvm/test/CodeGen/AMDGPU/GlobalISel/legalize-trunc.mir
@@ -215,9 +215,8 @@
 
     ; CHECK-LABEL: name: test_trunc_s16_to_s1
     ; CHECK: [[COPY:%[0-9]+]]:_(s32) = COPY $vgpr0
-    ; CHECK: [[TRUNC:%[0-9]+]]:_(s16) = G_TRUNC [[COPY]](s32)
-    ; CHECK: [[TRUNC1:%[0-9]+]]:_(s1) = G_TRUNC [[TRUNC]](s16)
-    ; CHECK: S_ENDPGM 0, implicit [[TRUNC1]](s1)
+    ; CHECK: [[TRUNC:%[0-9]+]]:_(s1) = G_TRUNC [[COPY]](s32)
+    ; CHECK: S_ENDPGM 0, implicit [[TRUNC]](s1)
     %0:_(s32) = COPY $vgpr0
     %1:_(s16) = G_TRUNC %0
     %2:_(s1) = G_TRUNC %1