diff --git a/clang/lib/CodeGen/CodeGenModule.cpp b/clang/lib/CodeGen/CodeGenModule.cpp
--- a/clang/lib/CodeGen/CodeGenModule.cpp
+++ b/clang/lib/CodeGen/CodeGenModule.cpp
@@ -2212,9 +2212,15 @@
                  *UnitGV = EmitAnnotationUnit(L),
                  *LineNoCst = EmitAnnotationLineNo(L);
 
+  llvm::Constant *ASZeroGV = GV;
+  if (GV->getAddressSpace() != 0) {
+    ASZeroGV = llvm::ConstantExpr::getAddrSpaceCast(
+                   GV, GV->getValueType()->getPointerTo(0));
+  }
+
   // Create the ConstantStruct for the global annotation.
   llvm::Constant *Fields[4] = {
-    llvm::ConstantExpr::getBitCast(GV, Int8PtrTy),
+    llvm::ConstantExpr::getBitCast(ASZeroGV, Int8PtrTy),
     llvm::ConstantExpr::getBitCast(AnnoGV, Int8PtrTy),
     llvm::ConstantExpr::getBitCast(UnitGV, Int8PtrTy),
     LineNoCst
diff --git a/clang/test/CodeGen/annotations-global.c b/clang/test/CodeGen/annotations-global.c
--- a/clang/test/CodeGen/annotations-global.c
+++ b/clang/test/CodeGen/annotations-global.c
@@ -3,6 +3,7 @@
 // RUN: FileCheck --check-prefix=A %s < %t1
 // RUN: FileCheck --check-prefix=BAR %s < %t1
 // RUN: FileCheck --check-prefix=FOOS %s < %t1
+// RUN: FileCheck --check-prefix=ADDRSPACE %s < %t1
 // END.
 
 static __attribute((annotate("sfoo_0"))) __attribute((annotate("sfoo_1"))) char sfoo;
@@ -14,17 +15,19 @@
   sfoo = 0;
 }
 
+__attribute((address_space(1))) __attribute__((annotate("addrspace1_ann"))) char addrspace1_var;
+
 // FOOS: target triple
 // FOOS: private unnamed_addr constant [7 x i8] c"sfoo_{{.}}\00", section "llvm.metadata"
 // FOOS: private unnamed_addr constant [7 x i8] c"sfoo_{{.}}\00", section "llvm.metadata"
 // FOOS-NOT: sfoo_
-// FOOS: @llvm.global.annotations = appending global [10 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @sfoo{{.*}}i8* @sfoo{{.*}}, section "llvm.metadata"
+// FOOS: @llvm.global.annotations = appending global [11 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @sfoo{{.*}}i8* @sfoo{{.*}}, section "llvm.metadata"
 
 // FOO: target triple
 // FOO: private unnamed_addr constant [6 x i8] c"foo_{{.}}\00", section "llvm.metadata"
 // FOO: private unnamed_addr constant [6 x i8] c"foo_{{.}}\00", section "llvm.metadata"
 // FOO-NOT: foo_
-// FOO: @llvm.global.annotations = appending global [10 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @foo{{.*}}i8* @foo{{.*}}, section "llvm.metadata"
+// FOO: @llvm.global.annotations = appending global [11 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @foo{{.*}}i8* @foo{{.*}}, section "llvm.metadata"
 
 // A: target triple
 // A: private unnamed_addr constant [8 x i8] c"ann_a_{{.}}\00", section "llvm.metadata"
@@ -32,10 +35,13 @@
 // A: private unnamed_addr constant [8 x i8] c"ann_a_{{.}}\00", section "llvm.metadata"
 // A: private unnamed_addr constant [8 x i8] c"ann_a_{{.}}\00", section "llvm.metadata"
 // A-NOT: ann_a_
-// A: @llvm.global.annotations = appending global [10 x { i8*, i8*, i8*, i32 }] {{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}, section "llvm.metadata"
+// A: @llvm.global.annotations = appending global [11 x { i8*, i8*, i8*, i32 }] {{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}i8* bitcast (void (i8*)* @a to i8*){{.*}}, section "llvm.metadata"
 
 // BAR: target triple
 // BAR: private unnamed_addr constant [6 x i8] c"bar_{{.}}\00", section "llvm.metadata"
 // BAR: private unnamed_addr constant [6 x i8] c"bar_{{.}}\00", section "llvm.metadata"
 // BAR-NOT: bar_
-// BAR: @llvm.global.annotations = appending global [10 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @a.bar{{.*}}i8* @a.bar{{.*}}, section "llvm.metadata"
+// BAR: @llvm.global.annotations = appending global [11 x { i8*, i8*, i8*, i32 }] {{.*}}i8* @a.bar{{.*}}i8* @a.bar{{.*}}, section "llvm.metadata"
+
+// ADDRSPACE: target triple
+// ADDRSPACE: @llvm.global.annotations = appending global {{.*}} addrspacecast (i8 addrspace(1)* @addrspace1_var to i8*), {{.*}}