diff --git a/llvm/include/llvm/Support/Compiler.h b/llvm/include/llvm/Support/Compiler.h
--- a/llvm/include/llvm/Support/Compiler.h
+++ b/llvm/include/llvm/Support/Compiler.h
@@ -406,10 +406,12 @@
 #if __has_feature(memory_sanitizer)
 # define LLVM_MEMORY_SANITIZER_BUILD 1
 # include <sanitizer/msan_interface.h>
+# define LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE __attribute__((no_sanitize_memory))
 #else
 # define LLVM_MEMORY_SANITIZER_BUILD 0
 # define __msan_allocated_memory(p, size)
 # define __msan_unpoison(p, size)
+# define LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE
 #endif
 
 /// \macro LLVM_ADDRESS_SANITIZER_BUILD
diff --git a/llvm/lib/IR/Metadata.cpp b/llvm/lib/IR/Metadata.cpp
--- a/llvm/lib/IR/Metadata.cpp
+++ b/llvm/lib/IR/Metadata.cpp
@@ -489,7 +489,9 @@
   return Ptr;
 }
 
-void MDNode::operator delete(void *Mem) {
+// Repress memory sanitization, due to use-after-destroy by operator
+// delete. Bug report 24578 identifies this issue.
+LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE void MDNode::operator delete(void *Mem) {
   MDNode *N = static_cast<MDNode *>(Mem);
   size_t OpSize = N->NumOperands * sizeof(MDOperand);
   OpSize = alignTo(OpSize, alignof(uint64_t));
diff --git a/llvm/lib/IR/User.cpp b/llvm/lib/IR/User.cpp
--- a/llvm/lib/IR/User.cpp
+++ b/llvm/lib/IR/User.cpp
@@ -162,7 +162,9 @@
 //                         User operator delete Implementation
 //===----------------------------------------------------------------------===//
 
-void User::operator delete(void *Usr) {
+// Repress memory sanitization, due to use-after-destroy by operator
+// delete. Bug report 24578 identifies this issue.
+LLVM_NO_SANITIZE_MEMORY_ATTRIBUTE void User::operator delete(void *Usr) {
   // Hung off uses use a single Use* before the User, while other subclasses
   // use a Use[] allocated prior to the user.
   User *Obj = static_cast<User *>(Usr);