diff --git a/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp b/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
--- a/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
+++ b/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
@@ -714,6 +714,12 @@
   // Emit call site entries for each call or tail call in the function.
   for (const MachineBasicBlock &MBB : MF) {
     for (const MachineInstr &MI : MBB.instrs()) {
+      // Bundles with call in them will pass the isCall() test below but do not
+      // have callee operand information so skip them here. Iterator will
+      // eventually reach the call MI.
+      if (MI.isBundle())
+        continue;
+
       // Skip instructions which aren't calls. Both calls and tail-calling jump
       // instructions (e.g TAILJMPd64) are classified correctly here.
       if (!MI.isCall())
@@ -748,19 +754,27 @@
 
       bool IsTail = TII->isTailCall(MI);
 
+      // If MI is in a bundle, the label was created after the bundle since
+      // EmitFunctionBody iterates over top-level MIs. Get that top-level MI
+      // to search for that label below.
+      const MachineInstr *TopLevelCallMI =
+          MI.isInsideBundle() ? &*getBundleStart(MI.getIterator()) : &MI;
+
       // For tail calls, for non-gdb tuning, no return PC information is needed.
       // For regular calls (and tail calls in GDB tuning), the return PC
       // is needed to disambiguate paths in the call graph which could lead to
       // some target function.
       const MCExpr *PCOffset =
-          (IsTail && !tuneForGDB()) ? nullptr
-                                    : getFunctionLocalOffsetAfterInsn(&MI);
+          (IsTail && !tuneForGDB())
+              ? nullptr
+              : getFunctionLocalOffsetAfterInsn(TopLevelCallMI);
 
       // Address of a call-like instruction for a normal call or a jump-like
       // instruction for a tail call. This is needed for GDB + DWARF 4 tuning.
       const MCSymbol *PCAddr =
-          ApplyGNUExtensions ? const_cast<MCSymbol*>(getLabelAfterInsn(&MI))
-                             : nullptr;
+          ApplyGNUExtensions
+              ? const_cast<MCSymbol *>(getLabelAfterInsn(TopLevelCallMI))
+              : nullptr;
 
       assert((IsTail || PCOffset || PCAddr) &&
              "Call without return PC information");
diff --git a/llvm/test/DebugInfo/Hexagon/bundled-call-pr44001.ll b/llvm/test/DebugInfo/Hexagon/bundled-call-pr44001.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/DebugInfo/Hexagon/bundled-call-pr44001.ll
@@ -0,0 +1,45 @@
+; Check absence of assert failure
+; RUN: llc -O3 -o /dev/null < %s
+
+; ModuleID = 'bundled-call-pr44001.c'
+source_filename = "bundled-call-pr44001.c"
+target datalayout = "e-m:e-p:32:32:32-a:0-n16:32-i64:64:64-i32:32:32-i16:16:16-i1:8:8-f32:32:32-f64:64:64-v32:32:32-v64:64:64-v512:512:512-v1024:1024:1024-v2048:2048:2048"
+target triple = "hexagon-unknown-unknown-elf"
+
+; Function Attrs: nounwind
+define dso_local i32 @foo(i32 %cond) local_unnamed_addr !dbg !12 {
+entry:
+  call void @llvm.dbg.value(metadata i32 %cond, metadata !14, metadata !DIExpression()), !dbg !15
+  %call = tail call i32 @bar(i32 %cond), !dbg !16
+  %add = add nsw i32 %call, 1, !dbg !17
+  ret i32 %add, !dbg !18
+}
+
+declare !dbg !4 dso_local i32 @bar(i32) local_unnamed_addr
+
+; Function Attrs: nounwind readnone speculatable willreturn
+declare void @llvm.dbg.value(metadata, metadata, metadata)
+
+!llvm.dbg.cu = !{!0}
+!llvm.module.flags = !{!8, !9, !10}
+!llvm.ident = !{!11}
+
+!0 = distinct !DICompileUnit(language: DW_LANG_C99, file: !1, producer: "clang version 10.0.0", isOptimized: true, runtimeVersion: 0, emissionKind: FullDebug, enums: !2, retainedTypes: !3, nameTableKind: None)
+!1 = !DIFile(filename: "bundled-call-pr44001.ll", directory: "/")
+!2 = !{}
+!3 = !{!4}
+!4 = !DISubprogram(name: "bar", scope: !1, file: !1, line: 1, type: !5, flags: DIFlagPrototyped, spFlags: DISPFlagOptimized, retainedNodes: !2)
+!5 = !DISubroutineType(types: !6)
+!6 = !{!7, !7}
+!7 = !DIBasicType(name: "int", size: 32, encoding: DW_ATE_signed)
+!8 = !{i32 2, !"Dwarf Version", i32 4}
+!9 = !{i32 2, !"Debug Info Version", i32 3}
+!10 = !{i32 1, !"wchar_size", i32 4}
+!11 = !{!"clang version 10.0.0"}
+!12 = distinct !DISubprogram(name: "foo", scope: !1, file: !1, line: 4, type: !5, scopeLine: 4, flags: DIFlagPrototyped | DIFlagAllCallsDescribed, spFlags: DISPFlagDefinition | DISPFlagOptimized, unit: !0, retainedNodes: !13)
+!13 = !{!14}
+!14 = !DILocalVariable(name: "cond", arg: 1, scope: !12, file: !1, line: 4, type: !7)
+!15 = !DILocation(line: 0, scope: !12)
+!16 = !DILocation(line: 5, column: 10, scope: !12)
+!17 = !DILocation(line: 5, column: 20, scope: !12)
+!18 = !DILocation(line: 5, column: 3, scope: !12)
diff --git a/llvm/test/DebugInfo/Hexagon/lit.local.cfg b/llvm/test/DebugInfo/Hexagon/lit.local.cfg
new file mode 100644
--- /dev/null
+++ b/llvm/test/DebugInfo/Hexagon/lit.local.cfg
@@ -0,0 +1,2 @@
+if not 'Hexagon' in config.root.targets:
+    config.unsupported = True