Index: lib/Target/AMDGPU/SIInsertSkips.cpp
===================================================================
--- lib/Target/AMDGPU/SIInsertSkips.cpp
+++ lib/Target/AMDGPU/SIInsertSkips.cpp
@@ -135,7 +135,8 @@
         return true;
 
       // These instructions are potentially expensive even if EXEC = 0.
-      if (TII->isSMRD(*I) || TII->isVMEM(*I) || I->getOpcode() == AMDGPU::S_WAITCNT)
+      if (TII->isSMRD(*I) || TII->isVMEM(*I) || TII->isFLAT(*I) ||
+          I->getOpcode() == AMDGPU::S_WAITCNT)
         return true;
 
       ++NumInstr;
Index: test/CodeGen/AMDGPU/insert-skips-flat-vmem.mir
===================================================================
--- /dev/null
+++ test/CodeGen/AMDGPU/insert-skips-flat-vmem.mir
@@ -0,0 +1,58 @@
+# NOTE: Assertions have been autogenerated by utils/update_mir_test_checks.py
+# RUN: llc -march=amdgcn -mcpu=polaris10 -run-pass si-insert-skips -amdgpu-skip-threshold=1 %s -o - | FileCheck %s
+
+---
+
+name: skip_execz_flat
+body: |
+  ; CHECK-LABEL: name: skip_execz_flat
+  ; CHECK: bb.0:
+  ; CHECK:   successors: %bb.1(0x80000000)
+  ; CHECK:   SI_MASK_BRANCH %bb.2, implicit $exec
+  ; CHECK:   S_CBRANCH_EXECZ %bb.2, implicit $exec
+  ; CHECK: bb.1:
+  ; CHECK:   successors: %bb.2(0x80000000)
+  ; CHECK:   $vgpr0 = V_MOV_B32_e32 0, implicit $exec
+  ; CHECK:   FLAT_STORE_DWORD undef $vgpr1_vgpr2, $vgpr0, 0, 0, 0, 0, implicit $exec, implicit $flat_scr
+  ; CHECK: bb.2:
+  ; CHECK:   S_ENDPGM 0
+  bb.0:
+    successors: %bb.1
+    SI_MASK_BRANCH %bb.2, implicit $exec
+
+  bb.1:
+    successors: %bb.2
+    $vgpr0 = V_MOV_B32_e32 0, implicit $exec
+    FLAT_STORE_DWORD undef $vgpr1_vgpr2, $vgpr0, 0, 0, 0, 0, implicit $exec, implicit $flat_scr
+
+  bb.2:
+    S_ENDPGM 0
+...
+
+---
+
+name: skip_execz_mubuf
+body: |
+  ; CHECK-LABEL: name: skip_execz_mubuf
+  ; CHECK: bb.0:
+  ; CHECK:   successors: %bb.1(0x80000000)
+  ; CHECK:   SI_MASK_BRANCH %bb.2, implicit $exec
+  ; CHECK:   S_CBRANCH_EXECZ %bb.2, implicit $exec
+  ; CHECK: bb.1:
+  ; CHECK:   successors: %bb.2(0x80000000)
+  ; CHECK:   $vgpr0 = V_MOV_B32_e32 0, implicit $exec
+  ; CHECK:   BUFFER_STORE_DWORD_OFFSET $vgpr0, undef $sgpr0_sgpr1_sgpr2_sgpr3, undef $sgpr4, 0, 0, 0, 0, 0, implicit $exec
+  ; CHECK: bb.2:
+  ; CHECK:   S_ENDPGM 0
+  bb.0:
+    successors: %bb.1
+    SI_MASK_BRANCH %bb.2, implicit $exec
+
+  bb.1:
+    successors: %bb.2
+    $vgpr0 = V_MOV_B32_e32 0, implicit $exec
+    BUFFER_STORE_DWORD_OFFSET $vgpr0, undef $sgpr0_sgpr1_sgpr2_sgpr3, undef $sgpr4, 0, 0, 0, 0, 0, implicit $exec
+
+  bb.2:
+    S_ENDPGM 0
+...