diff --git a/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp b/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
--- a/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
+++ b/llvm/lib/CodeGen/AsmPrinter/DwarfDebug.cpp
@@ -1980,8 +1980,12 @@
   Asm->OutStreamer->AddComment("Loc expr size");
   if (getDwarfVersion() >= 5)
     Asm->EmitULEB128(DebugLocs.getBytes(Entry).size());
-  else
+  else if (DebugLocs.getBytes(Entry).size() <= std::numeric_limits<uint16_t>::max())
     Asm->emitInt16(DebugLocs.getBytes(Entry).size());
+  else
+    // The entry is too big to fit into 16 bit, drop it as there is nothing we
+    // can do.
+    return;
   // Emit the entry.
   APByteStreamer Streamer(*Asm);
   emitDebugLocEntry(Streamer, Entry);