diff --git a/llvm/lib/Transforms/Utils/LoopRotationUtils.cpp b/llvm/lib/Transforms/Utils/LoopRotationUtils.cpp
--- a/llvm/lib/Transforms/Utils/LoopRotationUtils.cpp
+++ b/llvm/lib/Transforms/Utils/LoopRotationUtils.cpp
@@ -462,9 +462,8 @@
     for (BasicBlock *ExitPred : ExitPreds) {
       // We only need to split loop exit edges.
       Loop *PredLoop = LI->getLoopFor(ExitPred);
-      if (!PredLoop || PredLoop->contains(Exit))
-        continue;
-      if (isa<IndirectBrInst>(ExitPred->getTerminator()))
+      if (!PredLoop || PredLoop->contains(Exit) ||
+          ExitPred->getTerminator()->isIndirectTerminator())
         continue;
       SplitLatchEdge |= L->getLoopLatch() == ExitPred;
       BasicBlock *ExitSplit = SplitCriticalEdge(
diff --git a/llvm/test/Transforms/LoopRotate/callbr.ll b/llvm/test/Transforms/LoopRotate/callbr.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/Transforms/LoopRotate/callbr.ll
@@ -0,0 +1,84 @@
+; RUN: opt < %s -S -loop-rotate -o - -verify-loop-info -verify-dom-info | FileCheck %s
+; RUN: opt < %s -S -loop-rotate -o - -verify-loop-info -verify-dom-info -enable-mssa-loop-dependency=true | FileCheck %s
+
+@d = external dso_local local_unnamed_addr global i64, align 8
+@f = external dso_local local_unnamed_addr global i32, align 4
+@g = external dso_local local_unnamed_addr global i32, align 4
+@i = external dso_local local_unnamed_addr global i32, align 4
+@h = external dso_local local_unnamed_addr global i32, align 4
+
+define dso_local i32 @o() #0 {
+  %1 = alloca [1 x i32], align 4
+  %2 = load i8*, i8** bitcast (i64* @d to i8**), align 8, !tbaa !1
+  br label %3
+
+; <label>:3:                                      ; preds = %m.exit, %0
+  %4 = load i32, i32* @f, align 4, !tbaa !5
+  %5 = icmp eq i32 %4, 0
+  br i1 %5, label %16, label %6
+
+; <label>:6:                                      ; preds = %3
+  %7 = icmp ult i32 %4, 4
+  %8 = zext i1 %7 to i32
+  store i32 %8, i32* @g, align 4, !tbaa !5
+  %9 = bitcast [1 x i32]* %1 to i8*
+  %10 = call i32 @n(i8* nonnull %9, i8* %2)
+  %11 = icmp eq i32 %10, 0
+  br i1 %11, label %thread-pre-split, label %16
+
+thread-pre-split:                                 ; preds = %6
+  %.pr = load i32, i32* @i, align 4, !tbaa !5
+  br label %12
+
+; <label>:12:                                     ; preds = %j.exit.i, %thread-pre-split
+  %.1 = phi i32 [ %15, %j.exit.i ], [ undef, %thread-pre-split ]
+  %13 = icmp eq i32 %.pr, 0
+  br i1 %13, label %m.exit, label %14
+
+; <label>:14:                                     ; preds = %12
+  callbr void asm sideeffect "", "X,~{dirflag},~{fpsr},~{flags}"(i8* blockaddress(@o, %m.exit)) #1
+          to label %j.exit.i [label %m.exit], !srcloc !7
+
+j.exit.i:                                         ; preds = %14
+  %15 = tail call i32 asm "", "={ax},~{dirflag},~{fpsr},~{flags}"() #2, !srcloc !8
+  br label %12
+
+m.exit:                                           ; preds = %14, %12
+  %.1.lcssa = phi i32 [ %.1, %14 ], [ %.1, %12 ]
+  store i32 %.1.lcssa, i32* @h, align 4, !tbaa !5
+  br label %3
+
+; <label>:16:                                     ; preds = %6, %3
+  ret i32 undef
+}
+
+declare dso_local i32 @n(i8*, i8*) local_unnamed_addr #0
+
+attributes #0 = { "use-soft-float"="false" }
+attributes #1 = { nounwind }
+attributes #2 = { nounwind readnone }
+
+!llvm.ident = !{!0}
+
+!0 = !{!"clang version 9.0.0 (https://github.com/llvm/llvm-project.git d3b300358d649d55afbc7c9941429790cc0381c4)"}
+!1 = !{!2, !2, i64 0}
+!2 = !{!"long", !3, i64 0}
+!3 = !{!"omnipotent char", !4, i64 0}
+!4 = !{!"Simple C/C++ TBAA"}
+!5 = !{!6, !6, i64 0}
+!6 = !{!"int", !3, i64 0}
+!7 = !{i32 64}
+!8 = !{i32 122}
+
+; CHECK: @o
+; CHECK: .lr.ph2
+; CHECK: <label>:5
+; CHECK: thread-pre-split:
+; CHECK: .lr.ph:
+; CHECK: <label>:13:
+; CHECK: j.exit.i:
+; CHECK: .m.exit_crit_edge:
+; CHECK: m.exit:
+; CHECK: ._crit_edge:
+; CHECK: ._crit_edge3:
+; CHECK: <label>:17: