Index: llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
===================================================================
--- llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
+++ llvm/lib/Target/WebAssembly/WebAssemblyISelLowering.cpp
@@ -225,6 +225,9 @@
     }
   }
 
+  // Don't do anything clever with build_pairs
+  setOperationAction(ISD::BUILD_PAIR, MVT::i64, Expand);
+
   // Trap lowers to wasm unreachable
   setOperationAction(ISD::TRAP, MVT::Other, Legal);
 
Index: llvm/test/CodeGen/WebAssembly/build-pair.ll
===================================================================
--- /dev/null
+++ llvm/test/CodeGen/WebAssembly/build-pair.ll
@@ -0,0 +1,24 @@
+; RUN: llc < %s -asm-verbose=false -verify-machineinstrs -disable-wasm-fallthrough-return-opt -wasm-disable-explicit-locals -wasm-keep-registers -mattr=simd128 | FileCheck %s --check-prefixes CHECK
+
+target datalayout = "e-m:e-p:32:32-i64:64-n32:64-S128"
+target triple = "wasm32-unknown-unknown-wasm"
+
+; Test that BUILD_PAIR dag nodes are correctly lowered.
+
+; CHECK:      i32x4.extract_lane
+; CHECK-NEXT: i64.extend_i32_u
+; CHECK-NEXT: i32x4.extract_lane
+; CHECK-NEXT: i64.extend_i32_u
+; CHECK-NEXT: i64.const {{.*}} 32
+; CHECK-NEXT: i64.shl
+; CHECK-NEXT: i64.or
+; CHECK-NEXT: i64.store
+define void @build_pair_i32s() {
+entry:
+  %0 = load <4 x i32>, <4 x i32>* undef, align 16
+  %shuffle.i184 = shufflevector <4 x i32> %0, <4 x i32> undef, <4 x i32> <i32 2, i32 3, i32 undef, i32 undef>
+  %bc357 = bitcast <4 x i32> %shuffle.i184 to <2 x i64>
+  %1 = extractelement <2 x i64> %bc357, i32 0
+  store i64 %1, i64* undef, align 1
+  ret void
+}