Index: lib/Transforms/InstCombine/InstCombineAddSub.cpp
===================================================================
--- lib/Transforms/InstCombine/InstCombineAddSub.cpp
+++ lib/Transforms/InstCombine/InstCombineAddSub.cpp
@@ -1621,6 +1621,15 @@
       return BinaryOperator::CreateNeg(Y);
   }
 
+  // (sub (or A, B) (and A, B)) --> (xor A, B)
+  {
+    Value *A = nullptr, *B = nullptr;
+    if (match(Op1, m_And(m_Value(A), m_Value(B))) &&
+        (match(Op0, m_Or(m_Specific(A), m_Specific(B))) ||
+         match(Op0, m_Or(m_Specific(B), m_Specific(A)))))
+      return BinaryOperator::CreateXor(A, B);
+  }
+
   if (Op1->hasOneUse()) {
     Value *X = nullptr, *Y = nullptr, *Z = nullptr;
     Constant *C = nullptr;
Index: test/Transforms/InstCombine/sub.ll
===================================================================
--- test/Transforms/InstCombine/sub.ll
+++ test/Transforms/InstCombine/sub.ll
@@ -529,3 +529,13 @@
 ; CHECK-NEXT: [[ADD:%.*]] = add nsw i32 %x, -32768
 ; CHECK: ret i32 [[ADD]]
 }
+
+define i32 @test45(i32 %x, i32 %y) {
+ %or = or i32 %x, %y
+ %and = and i32 %x, %y
+ %sub = sub i32 %or, %and
+ ret i32 %sub
+; CHECK-LABEL: @test45(
+; CHECK-NEXT: %sub = xor i32 %x, %y
+; CHECK:ret i32 %sub
+}