Index: packages/Python/lldbsuite/test/expression_command/call-function/TestCallBuiltinFunction.py
===================================================================
--- packages/Python/lldbsuite/test/expression_command/call-function/TestCallBuiltinFunction.py
+++ packages/Python/lldbsuite/test/expression_command/call-function/TestCallBuiltinFunction.py
@@ -0,0 +1,53 @@
+"""
+Tests calling builtin functions using expression evaluation.
+"""
+
+from __future__ import print_function
+
+
+import lldb
+from lldbsuite.test.decorators import *
+from lldbsuite.test.lldbtest import *
+from lldbsuite.test import lldbutil
+
+
+class ExprCommandCallBuiltinFunction(TestBase):
+
+    mydir = TestBase.compute_mydir(__file__)
+
+    # Builtins are expanded by Clang, so debug info shouldn't matter.
+    NO_DEBUG_INFO_TESTCASE = True
+
+    def setUp(self):
+        TestBase.setUp(self)
+        # Find the line number to break for main.c.
+        self.line = line_number(
+            'main.cpp',
+            '// Please test these expressions while stopped at this line:')
+
+    def test(self):
+        self.build()
+
+        # Set breakpoint in main and run exe
+        self.runCmd("file " + self.getBuildArtifact("a.out"), CURRENT_EXECUTABLE_SET)
+        lldbutil.run_break_set_by_file_and_line(
+            self, "main.cpp", self.line, num_expected_locations=-1, loc_exact=True)
+
+        self.runCmd("run", RUN_SUCCEEDED)
+
+        interp = self.dbg.GetCommandInterpreter()
+        result = lldb.SBCommandReturnObject()
+
+        # Test different builtin functions.
+
+        interp.HandleCommand("expr __builtin_isinf(0.0f)", result)
+        self.assertEqual(result.GetOutput(), "(int) $0 = 0\n")
+
+        interp.HandleCommand("expr __builtin_isnormal(0.0f)", result)
+        self.assertEqual(result.GetOutput(), "(int) $1 = 0\n")
+
+        interp.HandleCommand("expr __builtin_constant_p(1)", result)
+        self.assertEqual(result.GetOutput(), "(int) $2 = 1\n")
+
+        interp.HandleCommand("expr __builtin_abs(-14)", result)
+        self.assertEqual(result.GetOutput(), "(int) $3 = 14\n")
Index: source/Plugins/ExpressionParser/Clang/ClangExpressionParser.h
===================================================================
--- source/Plugins/ExpressionParser/Clang/ClangExpressionParser.h
+++ source/Plugins/ExpressionParser/Clang/ClangExpressionParser.h
@@ -149,8 +149,6 @@
       m_file_manager; ///< The Clang file manager object used by the compiler
   std::unique_ptr<clang::CompilerInstance>
       m_compiler; ///< The Clang compiler used to parse expressions into IR
-  std::unique_ptr<clang::Builtin::Context>
-      m_builtin_context; ///< Context for Clang built-ins
   std::unique_ptr<clang::SelectorTable>
       m_selector_table; ///< Selector table for Objective-C methods
   std::unique_ptr<clang::CodeGenerator>
Index: source/Plugins/ExpressionParser/Clang/ClangExpressionParser.cpp
===================================================================
--- source/Plugins/ExpressionParser/Clang/ClangExpressionParser.cpp
+++ source/Plugins/ExpressionParser/Clang/ClangExpressionParser.cpp
@@ -508,12 +508,21 @@
   // 8. Most of this we get from the CompilerInstance, but we also want to give
   // the context an ExternalASTSource.
   m_selector_table.reset(new SelectorTable());
-  m_builtin_context.reset(new Builtin::Context());
+
+  // We enable all builtin functions beside the builtins from libc/libm (e.g.
+  // 'fopen'). Those libc functions are already correctly handled by LLDB, and
+  // additionally enabling them as expandable builtins is breaking Clang.
+  m_compiler->getLangOpts().NoBuiltin = true;
+
+  auto &PP = m_compiler->getPreprocessor();
+  auto &builtin_context = PP.getBuiltinInfo();
+  builtin_context.initializeBuiltins(PP.getIdentifierTable(),
+                                     m_compiler->getLangOpts());
 
   std::unique_ptr<clang::ASTContext> ast_context(
       new ASTContext(m_compiler->getLangOpts(), m_compiler->getSourceManager(),
                      m_compiler->getPreprocessor().getIdentifierTable(),
-                     *m_selector_table.get(), *m_builtin_context.get()));
+                     *m_selector_table.get(), builtin_context));
 
   ast_context->InitBuiltinTypes(m_compiler->getTarget());