Index: lib/Transforms/Utils/PromoteMemoryToRegister.cpp
===================================================================
--- lib/Transforms/Utils/PromoteMemoryToRegister.cpp
+++ lib/Transforms/Utils/PromoteMemoryToRegister.cpp
@@ -511,6 +511,11 @@
           !isKnownNonZero(ReplVal, DL, 0, AC, LI, &DT))
         addAssumeNonNull(AC, LI);
 
+      // If the replacement value is the load, this must occur in unreachable
+      // code.
+      if (ReplVal == LI)
+        ReplVal = UndefValue::get(LI->getType());
+
       LI->replaceAllUsesWith(ReplVal);
     }
 
Index: test/Transforms/Mem2Reg/pr37632-unreachable-list-of-stores.ll
===================================================================
--- /dev/null
+++ test/Transforms/Mem2Reg/pr37632-unreachable-list-of-stores.ll
@@ -0,0 +1,20 @@
+; RUN: opt -mem2reg < %s -S | FileCheck %s
+
+
+; CHECK-LABEL: void @patatino()
+; CHECK-NEXT: ret void
+
+; CHECK-LABEL: cantreachme:
+; CHECK-NEXT: %dec = add nsw i32 undef, -1
+; CHECK-NEXT: br label %cantreachme
+
+define void @patatino() {
+  %a = alloca i32, align 4
+  ret void
+cantreachme:
+  %dec = add nsw i32 %tmp, -1
+  store i32 %dec, i32* %a
+  store i32 %tmp, i32* %a
+  %tmp = load i32, i32* %a
+  br label %cantreachme
+}