Index: lit/CMakeLists.txt
===================================================================
--- lit/CMakeLists.txt
+++ lit/CMakeLists.txt
@@ -46,6 +46,7 @@
 
 # the value is not canonicalized within LLVM
 llvm_canonicalize_cmake_booleans(
+  LLDB_DISABLE_PYTHON
   LLVM_ENABLE_ZLIB)
 
 configure_lit_site_cfg(
Index: lit/Suite/lit.site.cfg.in
===================================================================
--- lit/Suite/lit.site.cfg.in
+++ lit/Suite/lit.site.cfg.in
@@ -13,6 +13,7 @@
 config.python_executable = "@PYTHON_EXECUTABLE@"
 config.dotest_path = "@LLDB_SOURCE_DIR@/test/dotest.py"
 config.dotest_args_str = "@LLDB_DOTEST_ARGS@"
+config.lldb_disable_python = @LLDB_DISABLE_PYTHON@
 
 
 # Additional dotest arguments can be passed to lit by providing a
Index: lit/Suite/lldbtest.py
===================================================================
--- lit/Suite/lldbtest.py
+++ lit/Suite/lldbtest.py
@@ -37,6 +37,9 @@
         if litConfig.noExecute:
             return lit.Test.PASS, ''
 
+        if test.config.lldb_disable_python:
+            return (lit.Test.UNSUPPORTED, 'Python module disabled')
+
         if test.config.unsupported:
             return (lit.Test.UNSUPPORTED, 'Test is unsupported')