Index: include/llvm/Transforms/Utils/SimplifyLibCalls.h
===================================================================
--- include/llvm/Transforms/Utils/SimplifyLibCalls.h
+++ include/llvm/Transforms/Utils/SimplifyLibCalls.h
@@ -150,6 +150,8 @@
   Value *optimizeIsDigit(CallInst *CI, IRBuilder<> &B);
   Value *optimizeIsAscii(CallInst *CI, IRBuilder<> &B);
   Value *optimizeToAscii(CallInst *CI, IRBuilder<> &B);
+  Value *optimizeAtoi(CallInst *CI, IRBuilder<> &B);
+  Value *optimizeStrtol(CallInst *CI, IRBuilder<> &B);
 
   // Formatting and IO Library Call Optimizations
   Value *optimizeErrorReporting(CallInst *CI, IRBuilder<> &B,
Index: lib/Transforms/Utils/SimplifyLibCalls.cpp
===================================================================
--- lib/Transforms/Utils/SimplifyLibCalls.cpp
+++ lib/Transforms/Utils/SimplifyLibCalls.cpp
@@ -1677,6 +1677,43 @@
                      ConstantInt::get(CI->getType(), 0x7F));
 }
 
+Value *LibCallSimplifier::optimizeAtoi(CallInst *CI, IRBuilder<> &B) {
+  StringRef Str;
+  if (!getConstantStringInfo(CI->getArgOperand(0), Str))
+    return nullptr;
+
+  std::locale Loc;
+  if (Loc.name() != "C") {
+    return nullptr;
+  }
+
+  return ConstantInt::get(CI->getType(), atoi(Str.str().c_str()));
+}
+
+Value *LibCallSimplifier::optimizeStrtol(CallInst *CI, IRBuilder<> &B) {
+  StringRef Str;
+  if (!getConstantStringInfo(CI->getArgOperand(0), Str))
+    return nullptr;
+
+  if (!isa<ConstantPointerNull>(CI->getArgOperand(1)))
+    return nullptr;
+
+  std::locale Loc;
+  if (Loc.name() != "C") {
+    return nullptr;
+  }
+
+  if (ConstantInt *CInt = dyn_cast<ConstantInt>(CI->getArgOperand(2))) {
+    errno = 0;
+    long int Result = strtol(Str.str().c_str(), nullptr, CInt->getSExtValue());
+    if (errno == ERANGE)
+      return nullptr;
+    return ConstantInt::get(CI->getType(), Result);
+  }
+
+  return nullptr;
+}
+
 //===----------------------------------------------------------------------===//
 // Formatting and IO Library Call Optimizations
 //===----------------------------------------------------------------------===//
@@ -2271,6 +2308,10 @@
       return optimizeIsAscii(CI, Builder);
     case LibFunc_toascii:
       return optimizeToAscii(CI, Builder);
+    case LibFunc_atoi:
+      return optimizeAtoi(CI, Builder);
+    case LibFunc_strtol:
+      return optimizeStrtol(CI, Builder);
     case LibFunc_printf:
       return optimizePrintF(CI, Builder);
     case LibFunc_sprintf:
Index: test/Transforms/InstCombine/str-int.ll
===================================================================
--- /dev/null
+++ test/Transforms/InstCombine/str-int.ll
@@ -0,0 +1,98 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py
+; RUN: opt < %s -instcombine -S | FileCheck %s
+
+@.str = private unnamed_addr constant [3 x i8] c"12\00", align 1
+@.str.1 = private unnamed_addr constant [2 x i8] c"0\00", align 1
+@.str.2 = private unnamed_addr constant [11 x i8] c"4294967296\00", align 1
+@.str.3 = private unnamed_addr constant [24 x i8] c"10000000000000000000000\00", align 1
+
+declare i64 @strtol(i8*, i8**, i32) #1
+declare i32 @atoi(i8*) #2
+
+define i64 @strtol_dec() #0 {
+; CHECK-LABEL: @strtol_dec(
+; CHECK-NEXT:    ret i64 12
+;
+  %call = call i64 @strtol(i8* getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i32 0, i32 0), i8** null, i32 10) #2
+  ret i64 %call
+}
+
+define i64 @strtol_base_zero() #0 {
+; CHECK-LABEL: @strtol_base_zero(
+; CHECK-NEXT:    ret i64 12
+;
+  %call = call i64 @strtol(i8* getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i32 0, i32 0), i8** null, i32 0) #2
+  ret i64 %call
+}
+
+define i64 @strtol_hex() #0 {
+; CHECK-LABEL: @strtol_hex(
+; CHECK-NEXT:    ret i64 18
+;
+  %call = call i64 @strtol(i8* getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i32 0, i32 0), i8** null, i32 16) #2
+  ret i64 %call
+}
+
+define i64 @strtol_endptr_not_null() #0 {
+; CHECK-LABEL: @strtol_endptr_not_null(
+; CHECK-NEXT:    [[END:%.*]] = alloca i8*, align 4
+; CHECK-NEXT:    [[CALL:%.*]] = call i64 @strtol(i8* getelementptr inbounds ([2 x i8], [2 x i8]* @.str.1, i64 0, i64 0), i8** nonnull [[END]], i32 10)
+; CHECK-NEXT:    ret i64 [[CALL]]
+;
+  %end = alloca i8*, align 4
+  %call = call i64 @strtol(i8* getelementptr inbounds ([2 x i8], [2 x i8]* @.str.1, i32 0, i32 0), i8** %end, i32 10) #2
+  ret i64 %call
+}
+
+define i32 @atoi_test() #0 {
+; CHECK-LABEL: @atoi_test(
+; CHECK-NEXT:    ret i32 12
+;
+  %call = call i32 @atoi(i8* getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i32 0, i32 0)) #4
+  ret i32 %call
+}
+
+define i64 @strtol_not_const_str(i8* %s) #0 {
+; CHECK-LABEL: @strtol_not_const_str(
+; CHECK-NEXT:    [[CALL:%.*]] = call i64 @strtol(i8* nocapture [[S:%.*]], i8** null, i32 10)
+; CHECK-NEXT:    ret i64 [[CALL]]
+;
+  %call = call i64 @strtol(i8* %s, i8** null, i32 10) #3
+  ret i64 %call
+}
+
+define i32 @atoi_not_const_str(i8* %s) #0 {
+; CHECK-LABEL: @atoi_not_const_str(
+; CHECK-NEXT:    [[CALL:%.*]] = call i32 @atoi(i8* [[S:%.*]])
+; CHECK-NEXT:    ret i32 [[CALL]]
+;
+  %call = call i32 @atoi(i8* %s) #4
+  ret i32 %call
+}
+
+define i64 @strtol_not_const_base(i32 %b) #0 {
+; CHECK-LABEL: @strtol_not_const_base(
+; CHECK-NEXT:    [[CALL:%.*]] = call i64 @strtol(i8* nocapture getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i64 0, i64 0), i8** null, i32 [[B:%.*]])
+; CHECK-NEXT:    ret i64 [[CALL]]
+;
+  %call = call i64 @strtol(i8* getelementptr inbounds ([3 x i8], [3 x i8]* @.str, i32 0, i32 0), i8** null, i32 %b) #2
+  ret i64 %call
+}
+
+define i64 @strtol_long_int() #0 {
+; CHECK-LABEL: @strtol_long_int(
+; CHECK-NEXT:    ret i64 4294967296
+;
+  %call = call i64 @strtol(i8* getelementptr inbounds ([11 x i8], [11 x i8]* @.str.2, i32 0, i32 0), i8** null, i32 10) #3
+  ret i64 %call
+}
+
+
+define i64 @strtol_errno() #0 {
+; CHECK-LABEL: @strtol_errno(
+; CHECK-NEXT:    [[CALL:%.*]] = call i64 @strtol(i8* nocapture getelementptr inbounds ([24 x i8], [24 x i8]* @.str.3, i64 0, i64 0), i8** null, i32 10)
+; CHECK-NEXT:    ret i64 [[CALL]]
+;
+  %call = call i64 @strtol(i8* nocapture getelementptr inbounds ([24 x i8], [24 x i8]* @.str.3, i64 0, i64 0), i8** null, i32 10) #2
+  ret i64 %call
+}