Index: include/llvm/CodeGen/ISDOpcodes.h
===================================================================
--- include/llvm/CodeGen/ISDOpcodes.h
+++ include/llvm/CodeGen/ISDOpcodes.h
@@ -186,7 +186,8 @@
     /// BUILD_PAIR - This is the opposite of EXTRACT_ELEMENT in some ways.
     /// Given two values of the same integer value type, this produces a value
     /// twice as big.  Like EXTRACT_ELEMENT, this can only be used before
-    /// legalization.
+    /// legalization. The lower part of the composite value should be in
+    /// element 0 and the upper part should be in element 1.
     BUILD_PAIR,
 
     /// MERGE_VALUES - This node takes multiple discrete operands and returns
Index: lib/CodeGen/SelectionDAG/DAGCombiner.cpp
===================================================================
--- lib/CodeGen/SelectionDAG/DAGCombiner.cpp
+++ lib/CodeGen/SelectionDAG/DAGCombiner.cpp
@@ -8634,6 +8634,13 @@
 
   LoadSDNode *LD1 = dyn_cast<LoadSDNode>(getBuildPairElt(N, 0));
   LoadSDNode *LD2 = dyn_cast<LoadSDNode>(getBuildPairElt(N, 1));
+
+  // A BUILD_PAIR is always having the least significant part in elt 0 and the
+  // most significant part in elt 1. So when combining into one large load, we
+  // need to consider the endianness.
+  if (DAG.getDataLayout().isBigEndian())
+    std::swap(LD1, LD2);
+
   if (!LD1 || !LD2 || !ISD::isNON_EXTLoad(LD1) || !LD1->hasOneUse() ||
       LD1->getAddressSpace() != LD2->getAddressSpace())
     return SDValue();