Index: lib/Target/X86/X86FrameLowering.cpp
===================================================================
--- lib/Target/X86/X86FrameLowering.cpp
+++ lib/Target/X86/X86FrameLowering.cpp
@@ -2577,6 +2577,7 @@
   unsigned Regs[2];
   unsigned FoundRegs = 0;
 
+  auto &MRI = MBB.getParent()->getRegInfo();
   auto RegMask = Prev->getOperand(1);
 
   auto &RegClass =
@@ -2590,6 +2591,10 @@
     if (!RegMask.clobbersPhysReg(Candidate))
       continue;
 
+    // Don't clobber reserved registers
+    if (MRI.isReserved(Candidate))
+      continue;
+
     bool IsDef = false;
     for (const MachineOperand &MO : Prev->implicit_operands()) {
       if (MO.isReg() && MO.isDef() &&
Index: test/CodeGen/X86/pop-stack-cleanup-msvc.ll
===================================================================
--- /dev/null
+++ test/CodeGen/X86/pop-stack-cleanup-msvc.ll
@@ -0,0 +1,26 @@
+; RUN: llc < %s | FileCheck %s
+
+target triple = "i686--windows-msvc"
+
+declare { i8*, i32 } @param2_ret2(i32, i32)
+declare i32 @__CxxFrameHandler3(...)
+
+
+define void @test_reserved_regs() minsize optsize personality i32 (...)* @__CxxFrameHandler3 {
+; CHECK-LABEL: test_reserved_regs:
+; CHECK: calll _param2_ret2
+; CHECK-NEXT: popl %ecx
+; CHECK-NEXT: popl %edi
+start:
+  %s = alloca i64
+  store i64 4, i64* %s
+  %0 = invoke { i8*, i32 } @param2_ret2(i32 0, i32 1)
+          to label %out unwind label %cleanup
+
+out:
+  ret void
+
+cleanup:
+  %cp = cleanuppad within none []
+  cleanupret from %cp unwind to caller
+}