Index: lib/Target/AMDGPU/AsmParser/AMDGPUAsmParser.cpp
===================================================================
--- lib/Target/AMDGPU/AsmParser/AMDGPUAsmParser.cpp
+++ lib/Target/AMDGPU/AsmParser/AMDGPUAsmParser.cpp
@@ -2455,6 +2455,12 @@
 }
 
 bool AMDGPUAsmParser::ParseDirectiveISAVersion() {
+  if (getSTI().getTargetTriple().getArch() != Triple::amdgcn) {
+    return Error(getParser().getTok().getLoc(),
+                 ".amd_amdgpu_isa directive is not available on non-amdgcn "
+                 "architectures");
+  }
+
   auto ISAVersionFromASM = getLexer().getTok().getStringContents();
   auto ISAVersionFromSTI = IsaInfo::getIsaVersionString(&getSTI());
 
@@ -2471,6 +2477,12 @@
 }
 
 bool AMDGPUAsmParser::ParseDirectiveHSAMetadata() {
+  if (getSTI().getTargetTriple().getOS() != Triple::AMDHSA) {
+    return Error(getParser().getTok().getLoc(),
+                 (Twine(HSAMD::AssemblerDirectiveBegin) + Twine(" directive is "
+                 "not available on non-amdhsa OSes")).str());
+  }
+
   std::string HSAMetadataString;
   raw_string_ostream YamlStream(HSAMetadataString);
 
@@ -2502,7 +2514,7 @@
 
   if (getLexer().is(AsmToken::Eof) && !FoundEnd) {
     return TokError(Twine("expected directive ") +
-                    Twine(HSAMD::AssemblerDirectiveEnd) + Twine("not found"));
+                    Twine(HSAMD::AssemblerDirectiveEnd) + Twine(" not found"));
   }
 
   YamlStream.flush();
@@ -2514,6 +2526,12 @@
 }
 
 bool AMDGPUAsmParser::ParseDirectivePALMetadata() {
+  if (getSTI().getTargetTriple().getOS() != Triple::AMDPAL) {
+    return Error(getParser().getTok().getLoc(),
+                 (Twine(PALMD::AssemblerDirective) + Twine(" directive is "
+                 "not available on non-amdpal OSes")).str());
+  }
+
   PALMD::Metadata PALMetadata;
   for (;;) {
     uint32_t Value;
Index: test/MC/AMDGPU/elf-notes-verify-amdgcn.s
===================================================================
--- /dev/null
+++ test/MC/AMDGPU/elf-notes-verify-amdgcn.s
@@ -0,0 +1,7 @@
+// RUN: not llvm-mc -arch amdgcn %s 2>&1 | FileCheck --check-prefix=GCN %s
+
+// GCN: error: .amd_amdgpu_hsa_metadata directive is not available on non-amdhsa OSes
+.amd_amdgpu_hsa_metadata
+
+// GCN: error: .amd_amdgpu_pal_metadata directive is not available on non-amdpal OSes
+.amd_amdgpu_pal_metadata
Index: test/MC/AMDGPU/elf-notes-verify-r600.s
===================================================================
--- /dev/null
+++ test/MC/AMDGPU/elf-notes-verify-r600.s
@@ -0,0 +1,10 @@
+// RUN: not llvm-mc -arch r600 %s 2>&1 | FileCheck --check-prefix=R600 %s
+
+// R600: error: .amd_amdgpu_isa directive is not available on non-amdgcn architectures
+.amd_amdgpu_isa "r600"
+
+// R600: error: .amd_amdgpu_hsa_metadata directive is not available on non-amdhsa OSes
+.amd_amdgpu_hsa_metadata
+
+// R600: error: .amd_amdgpu_pal_metadata directive is not available on non-amdpal OSes
+.amd_amdgpu_pal_metadata