Index: lib/Target/AMDGPU/SIInsertSkips.cpp
===================================================================
--- lib/Target/AMDGPU/SIInsertSkips.cpp
+++ lib/Target/AMDGPU/SIInsertSkips.cpp
@@ -132,6 +132,16 @@
           I->getOpcode() == AMDGPU::S_CBRANCH_VCCZ)
         return true;
 
+      // V_READFIRSTLANE/V_READLANE destination register may be used as operand
+      // by some SALU instruction. If exec mask is zero vector instruction
+      // defining the register that is used by the scalar one is not executed
+      // and scalar instruction will operate on undefined data. For
+      // V_READFIRSTLANE/V_READLANE we should avoid predicated execution.
+      if ((I->getOpcode() == AMDGPU::V_READFIRSTLANE_B32) ||
+          (I->getOpcode() == AMDGPU::V_READLANE_B32)) {
+        return true;
+      }
+
       if (I->isInlineAsm()) {
         const MCAsmInfo *MAI = MF->getTarget().getMCAsmInfo();
         const char *AsmStr = I->getOperand(0).getSymbolName();
Index: test/CodeGen/AMDGPU/readlane_exec0.mir
===================================================================
--- /dev/null
+++ test/CodeGen/AMDGPU/readlane_exec0.mir
@@ -0,0 +1,32 @@
+# RUN: llc -o - %s -march=amdgcn -mcpu=fiji  -run-pass=si-insert-skips -verify-machineinstrs | FileCheck -check-prefix=GCN %s
+
+# GCN-LABEL: readlane_exec0
+# GCN: bb.0
+# GCN: S_CBRANCH_EXECZ %bb.2
+
+---
+name: readlane_exec0
+
+body:       |
+  bb.0:
+    successors: %bb.1, %bb.2
+    liveins: %vgpr1_vgpr2:0x00000001, %vgpr2_vgpr3:0x00000003
+
+    %vgpr4 = V_AND_B32_e32 1, %vgpr1, implicit %exec
+    V_CMP_EQ_U32_e32 1, killed %vgpr4, implicit-def %vcc, implicit %exec
+    %sgpr0_sgpr1 = S_AND_SAVEEXEC_B64 killed %vcc, implicit-def %exec, implicit-def %scc, implicit %exec
+    SI_MASK_BRANCH %bb.2, implicit %exec
+    S_BRANCH %bb.1
+
+  bb.1:
+    
+   %sgpr10 = V_READFIRSTLANE_B32 %vgpr2, implicit %exec
+   %sgpr11 = V_READFIRSTLANE_B32 %vgpr3, implicit %exec
+   %sgpr10 = S_LOAD_DWORD_IMM killed %sgpr10_sgpr11, 0, 0
+   S_WAITCNT 127
+   %vgpr0 = V_XOR_B32_e32 killed %sgpr10, killed %vgpr0, implicit %exec
+   
+  bb.2:
+
+    %exec = S_OR_B64 %exec, killed %sgpr0_sgpr1, implicit-def %scc
+...