Index: cfe/trunk/lib/StaticAnalyzer/Core/RegionStore.cpp
===================================================================
--- cfe/trunk/lib/StaticAnalyzer/Core/RegionStore.cpp
+++ cfe/trunk/lib/StaticAnalyzer/Core/RegionStore.cpp
@@ -409,6 +409,19 @@
 
   // BindDefault is only used to initialize a region with a default value.
   StoreRef BindDefault(Store store, const MemRegion *R, SVal V) override {
+    // FIXME: The offsets of empty bases can be tricky because of
+    // of the so called "empty base class optimization".
+    // If a base class has been optimized out
+    // we should not try to create a binding, otherwise we should.
+    // Unfortunately, at the moment ASTRecordLayout doesn't expose
+    // the actual sizes of the empty bases
+    // and trying to infer them from offsets/alignments
+    // seems to be error-prone and non-trivial because of the trailing padding.
+    // As a temporary mitigation we don't create bindings for empty bases.
+    if (R->getKind() == MemRegion::CXXBaseObjectRegionKind &&
+        cast<CXXBaseObjectRegion>(R)->getDecl()->isEmpty())
+      return StoreRef(store, *this);
+
     RegionBindingsRef B = getRegionBindings(store);
     assert(!B.lookup(R, BindingKey::Direct));
 
Index: cfe/trunk/test/Analysis/ctor.mm
===================================================================
--- cfe/trunk/test/Analysis/ctor.mm
+++ cfe/trunk/test/Analysis/ctor.mm
@@ -704,3 +704,20 @@
     };
   }
 }
+
+namespace NoCrashOnEmptyBaseOptimization {
+  struct NonEmptyBase {
+    int X;
+    explicit NonEmptyBase(int X) : X(X) {}
+  };
+
+  struct EmptyBase {};
+
+  struct S : NonEmptyBase, EmptyBase {
+    S() : NonEmptyBase(0), EmptyBase() {}
+  };
+
+  void testSCtorNoCrash() {
+    S s;
+  }
+}