Index: lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
===================================================================
--- lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
+++ lib/Transforms/InstCombine/InstCombineAndOrXor.cpp
@@ -126,21 +126,6 @@
 
   switch (Op->getOpcode()) {
   default: break;
-  case Instruction::Or:
-    if (Op->hasOneUse()){
-      ConstantInt *TogetherCI = dyn_cast<ConstantInt>(Together);
-      if (TogetherCI && !TogetherCI->isZero()){
-        // (X | C1) & C2 --> (X & (C2^(C1&C2))) | C1
-        // NOTE: This reduces the number of bits set in the & mask, which
-        // can expose opportunities for store narrowing.
-        Together = ConstantExpr::getXor(AndRHS, Together);
-        Value *And = Builder.CreateAnd(X, Together);
-        And->takeName(Op);
-        return BinaryOperator::CreateOr(And, OpRHS);
-      }
-    }
-
-    break;
   case Instruction::Add:
     if (Op->hasOneUse()) {
       // Adding a one to a single bit bit-field should be turned into an XOR
@@ -1223,6 +1208,22 @@
       return BinaryOperator::CreateXor(And, NewC);
     }
 
+    const APInt *OrC;
+    if (match(Op0, m_OneUse(m_Or(m_Value(X), m_APInt(OrC))))) {
+      // (X | C1) & C2 --> (X & C2^(C1&C2)) | (C1&C2)
+      // NOTE: This reduces the number of bits set in the & mask, which
+      // can expose opportunities for store narrowing for scalars.
+      // NOTE: SimplifyDemandedBits should have already removed bits from C1
+      // that aren't set in C2. Meaning we can replace (C1&C2) with C1 in
+      // above, but this feels safer.
+      APInt Together = *C & *OrC;
+      Value *And = Builder.CreateAnd(X, ConstantInt::get(I.getType(),
+                                                         Together ^ *C));
+      And->takeName(Op0);
+      return BinaryOperator::CreateOr(And, ConstantInt::get(I.getType(),
+                                                            Together));
+    }
+
     // If the mask is only needed on one incoming arm, push the 'and' op up.
     if (match(Op0, m_OneUse(m_Xor(m_Value(X), m_Value(Y)))) ||
         match(Op0, m_OneUse(m_Or(m_Value(X), m_Value(Y))))) {
Index: test/Transforms/InstCombine/or.ll
===================================================================
--- test/Transforms/InstCombine/or.ll
+++ test/Transforms/InstCombine/or.ll
@@ -268,6 +268,21 @@
   ret i32 %E
 }
 
+define <2 x i32> @test30vec(<2 x i32> %A) {
+; CHECK-LABEL: @test30vec(
+; CHECK-NEXT:    [[C:%.*]] = and <2 x i32> [[A:%.*]], <i32 -65536, i32 -65536>
+; CHECK-NEXT:    [[B:%.*]] = and <2 x i32> [[A]], <i32 7224, i32 7224>
+; CHECK-NEXT:    [[D:%.*]] = or <2 x i32> [[B]], <i32 32962, i32 32962>
+; CHECK-NEXT:    [[E:%.*]] = or <2 x i32> [[D]], [[C]]
+; CHECK-NEXT:    ret <2 x i32> [[E]]
+;
+  %B = or <2 x i32> %A, <i32 32962, i32 32962>
+  %C = and <2 x i32> %A, <i32 -65536, i32 -65536>
+  %D = and <2 x i32> %B, <i32 40186, i32 40186>
+  %E = or <2 x i32> %D, %C
+  ret <2 x i32> %E
+}
+
 ; PR4216
 define i64 @test31(i64 %A) {
 ; CHECK-LABEL: @test31(
@@ -285,6 +300,22 @@
   ret i64 %F
 }
 
+define <2 x i64> @test31vec(<2 x i64> %A) {
+; CHECK-LABEL: @test31vec(
+; CHECK-NEXT:    [[E:%.*]] = and <2 x i64> [[A:%.*]], <i64 4294908984, i64 4294908984>
+; CHECK-NEXT:    [[F:%.*]] = or <2 x i64> [[E]], <i64 32962, i64 32962>
+; CHECK-NEXT:    ret <2 x i64> [[F]]
+;
+  %B = or <2 x i64> %A, <i64 194, i64 194>
+  %D = and <2 x i64> %B, <i64 250, i64 250>
+
+  %C = or <2 x i64> %A, <i64 32768, i64 32768>
+  %E = and <2 x i64> %C, <i64 4294941696, i64 4294941696>
+
+  %F = or <2 x i64> %D, %E
+  ret <2 x i64> %F
+}
+
 ; codegen is mature enough to handle vector selects.
 define <4 x i32> @test32(<4 x i1> %and.i1352, <4 x i32> %vecinit6.i176, <4 x i32> %vecinit6.i191) {
 ; CHECK-LABEL: @test32(