Index: include/llvm/Passes/PassBuilder.h
===================================================================
--- include/llvm/Passes/PassBuilder.h
+++ include/llvm/Passes/PassBuilder.h
@@ -29,10 +29,14 @@
 
 /// A struct capturing PGO tunables.
 struct PGOOptions {
-  std::string ProfileGenFile = "";
-  std::string ProfileUseFile = "";
-  std::string SampleProfileFile = "";
-  bool RunProfileGen = false;
+  PGOOptions(std::string ProfileGenFile = "", std::string ProfileUseFile = "",
+             std::string SampleProfileFile = "", bool RunProfileGen = false)
+      : ProfileGenFile(ProfileGenFile), ProfileUseFile(ProfileUseFile),
+        SampleProfileFile(SampleProfileFile), RunProfileGen(RunProfileGen) {}
+  std::string ProfileGenFile;
+  std::string ProfileUseFile;
+  std::string SampleProfileFile;
+  bool RunProfileGen;
 };
 
 /// \brief This class provides access to building LLVM's passes.
Index: lib/Passes/PassBuilder.cpp
===================================================================
--- lib/Passes/PassBuilder.cpp
+++ lib/Passes/PassBuilder.cpp
@@ -172,6 +172,11 @@
     "enable-npm-gvn-sink", cl::init(false), cl::Hidden,
     cl::desc("Enable the GVN hoisting pass for the new PM (default = off)"));
 
+static cl::opt<std::string> PGOOptString(
+    "pgo-opt", cl::init(""), cl::Hidden,
+    cl::desc("PGOOpt string in the format of "
+             "{gen|use|sample_gen|sample_use}=value"));
+
 static Regex DefaultAliasRegex(
     "^(default|thinlto-pre-link|thinlto|lto-pre-link|lto)<(O[0123sz])>$");
 
@@ -1101,6 +1106,27 @@
   return false;
 }
 
+/// Processes user specifiy -pgo-opt option to override PGOOpt.
+static void processPGOOpt(Optional<PGOOptions> &PGOOpt) {
+  if (PGOOptString.empty())
+    return;
+
+  auto pos = PGOOptString.find('=');
+  if (pos == std::string::npos)
+    report_fatal_error("Invalid -pgo-opt.");
+
+  std::string K = PGOOptString.substr(0, pos);
+  std::string V = PGOOptString.substr(pos + 1);
+
+  PGOOpt = StringSwitch<Optional<PGOOptions>>(K)
+               .Case("gen", PGOOptions(V, "", "", true))
+               .Case("use", PGOOptions("", V, "", false))
+               .Case("sample-use", PGOOptions("", "", V, false))
+               .Default(None);
+  if (!PGOOpt)
+    report_fatal_error("Invalid -pgo-opt.");
+}
+
 template <typename CallbacksT>
 static bool isModulePassName(StringRef Name, CallbacksT &Callbacks) {
   // Manually handle aliases for pre-configured pipeline fragments.
@@ -1668,6 +1694,8 @@
   if (!Pipeline || Pipeline->empty())
     return false;
 
+  processPGOOpt(PGOOpt);
+
   // If the first name isn't at the module layer, wrap the pipeline up
   // automatically.
   StringRef FirstName = Pipeline->front().Name;
Index: test/Other/Inputs/new-pm-pgo.prof
===================================================================
--- /dev/null
+++ test/Other/Inputs/new-pm-pgo.prof
@@ -0,0 +1 @@
+foo:0:0
Index: test/Other/Inputs/new-pm-pgo.proftext
===================================================================
--- /dev/null
+++ test/Other/Inputs/new-pm-pgo.proftext
@@ -0,0 +1 @@
+:ir
Index: test/Other/new-pm-pgo.ll
===================================================================
--- /dev/null
+++ test/Other/new-pm-pgo.ll
@@ -0,0 +1,12 @@
+; RUN: opt -debug-pass-manager -passes='default<O2>' -pgo-opt='gen=temp' %s 2>&1 |FileCheck %s --check-prefixes=GEN
+; RUN: llvm-profdata merge %S/Inputs/new-pm-pgo.proftext -o %t.profdata
+; RUN: opt -debug-pass-manager -passes='default<O2>' -pgo-opt='use=%t.profdata' %s 2>&1 |FileCheck %s --check-prefixes=USE
+; RUN: opt -debug-pass-manager -passes='default<O2>' -pgo-opt='sample-use=%S/Inputs/new-pm-pgo.prof' %s 2>&1 |FileCheck %s --check-prefixes=SAMPLE_USE
+;
+; GEN: Running pass: PGOInstrumentationGen
+; USE: Running pass: PGOInstrumentationUse
+; SAMPLE_USE: Running pass: SampleProfileLoaderPass
+
+define void @foo() {
+  ret void
+}