Index: lib/Transforms/Scalar/InferAddressSpaces.cpp
===================================================================
--- lib/Transforms/Scalar/InferAddressSpaces.cpp
+++ lib/Transforms/Scalar/InferAddressSpaces.cpp
@@ -327,6 +327,9 @@
         PushPtrOperand(Cmp->getOperand(0));
         PushPtrOperand(Cmp->getOperand(1));
       }
+    } else if (auto *ASC = dyn_cast<AddrSpaceCastInst>(&I)) {
+      if (!ASC->getType()->isVectorTy())
+        PushPtrOperand(ASC->getPointerOperand());
     }
   }
 
@@ -882,6 +885,15 @@
           }
         }
 
+        if (AddrSpaceCastInst *ASC = dyn_cast<AddrSpaceCastInst>(CurUser)) {
+          unsigned NewAS = NewV->getType()->getPointerAddressSpace();
+          if (ASC->getDestAddressSpace() == NewAS) {
+            ASC->replaceAllUsesWith(NewV);
+            ASC->eraseFromParent();
+            continue;
+          }
+        }
+
         // Otherwise, replaces the use with flat(NewV).
         if (Instruction *I = dyn_cast<Instruction>(V)) {
           BasicBlock::iterator InsertPos = std::next(I->getIterator());
Index: test/Transforms/InferAddressSpaces/AMDGPU/infer-addrspacecast.ll
===================================================================
--- /dev/null
+++ test/Transforms/InferAddressSpaces/AMDGPU/infer-addrspacecast.ll
@@ -0,0 +1,44 @@
+; RUN: opt -S -mtriple=amdgcn-amd-amdhsa -infer-address-spaces %s | FileCheck %s
+
+; Test that pure addrspacecast instructions not directly connected to
+; a memory operation are inferred.
+
+
+; CHECK-LABEL: @addrspacecast_gep_addrspacecast(
+; CHECK: %gep0 = getelementptr i32, i32 addrspace(3)* %ptr, i64 9
+; CHECK-NEXT: store i32 8, i32 addrspace(3)* %gep0, align 8
+; CHECK-NEXT: ret void
+define void @addrspacecast_gep_addrspacecast(i32 addrspace(3)* %ptr) {
+  %asc0 = addrspacecast i32 addrspace(3)* %ptr to i32 addrspace(4)*
+  %gep0 = getelementptr i32, i32 addrspace(4)* %asc0, i64 9
+  %asc1 = addrspacecast i32 addrspace(4)* %gep0 to i32 addrspace(3)*
+  store i32 8, i32 addrspace(3)* %asc1, align 8
+  ret void
+}
+
+; CHECK-LABEL: @addrspacecast_to_memory(
+; CHECK: %gep0 = getelementptr i32, i32 addrspace(3)* %ptr, i64 9
+; CHECK-NEXT: store volatile i32 addrspace(3)* %gep0, i32 addrspace(3)* addrspace(1)* undef
+; CHECK-NEXT: ret void
+define void @addrspacecast_to_memory(i32 addrspace(3)* %ptr) {
+  %asc0 = addrspacecast i32 addrspace(3)* %ptr to i32 addrspace(4)*
+  %gep0 = getelementptr i32, i32 addrspace(4)* %asc0, i64 9
+  %asc1 = addrspacecast i32 addrspace(4)* %gep0 to i32 addrspace(3)*
+  store volatile i32 addrspace(3)* %asc1, i32 addrspace(3)* addrspace(1)* undef
+  ret void
+}
+
+; CHECK-LABEL: @multiuse_addrspacecast_gep_addrspacecast(
+; CHECK: %1 = addrspacecast i32 addrspace(3)* %ptr to i32 addrspace(4)*
+; CHECK-NEXT: store volatile i32 addrspace(4)* %1, i32 addrspace(4)* addrspace(1)* undef
+; CHECK-NEXT: %gep0 = getelementptr i32, i32 addrspace(3)* %ptr, i64 9
+; CHECK-NEXT: store i32 8, i32 addrspace(3)* %gep0, align 8
+; CHECK-NEXT: ret void
+define void @multiuse_addrspacecast_gep_addrspacecast(i32 addrspace(3)* %ptr) {
+  %asc0 = addrspacecast i32 addrspace(3)* %ptr to i32 addrspace(4)*
+  store volatile i32 addrspace(4)* %asc0, i32 addrspace(4)* addrspace(1)* undef
+  %gep0 = getelementptr i32, i32 addrspace(4)* %asc0, i64 9
+  %asc1 = addrspacecast i32 addrspace(4)* %gep0 to i32 addrspace(3)*
+  store i32 8, i32 addrspace(3)* %asc1, align 8
+  ret void
+}
Index: test/Transforms/InferAddressSpaces/AMDGPU/infer-getelementptr.ll
===================================================================
--- test/Transforms/InferAddressSpaces/AMDGPU/infer-getelementptr.ll
+++ test/Transforms/InferAddressSpaces/AMDGPU/infer-getelementptr.ll
@@ -5,10 +5,20 @@
 
 @lds = internal unnamed_addr addrspace(3) global [648 x double] undef, align 8
 
+; CHECK-LABEL: @simplified_constexpr_gep_addrspacecast(
+; CHECK: %gep0 = getelementptr inbounds double, double addrspace(3)* getelementptr inbounds ([648 x double], [648 x double] addrspace(3)* @lds, i64 0, i64 384), i64 %idx0
+; CHECK-NEXT: store double 1.000000e+00, double addrspace(3)* %gep0, align 8
+define void @simplified_constexpr_gep_addrspacecast(i64 %idx0, i64 %idx1) {
+  %gep0 = getelementptr inbounds double, double addrspace(4)* addrspacecast (double addrspace(3)* getelementptr inbounds ([648 x double], [648 x double] addrspace(3)* @lds, i64 0, i64 384) to double addrspace(4)*), i64 %idx0
+  %asc = addrspacecast double addrspace(4)* %gep0 to double addrspace(3)*
+  store double 1.000000e+00, double addrspace(3)* %asc, align 8
+  ret void
+}
+
+; FIXME: Should be able to eliminate inner constantexpr addrspacecast.
 ; CHECK-LABEL: @constexpr_gep_addrspacecast(
-; CHECK: %gep0 = getelementptr inbounds double, double addrspace(4)* addrspacecast (double addrspace(3)* getelementptr inbounds ([648 x double], [648 x double] addrspace(3)* @lds, i64 0, i64 384) to double addrspace(4)*), i64 %idx0
-; CHECK-NEXT: %asc = addrspacecast double addrspace(4)* %gep0 to double addrspace(3)*
-; CHECK-NEXT: store double 1.000000e+00, double addrspace(3)* %asc
+; CHECK: %gep0 = getelementptr inbounds double, double addrspace(3)* addrspacecast (double addrspace(4)* getelementptr ([648 x double], [648 x double] addrspace(4)* addrspacecast ([648 x double] addrspace(3)* @lds to [648 x double] addrspace(4)*), i64 0, i64 384) to double addrspace(3)*), i64 %idx0
+; CHECK-NEXT: store double 1.000000e+00, double addrspace(3)* %gep0, align 8
 define void @constexpr_gep_addrspacecast(i64 %idx0, i64 %idx1) {
   %gep0 = getelementptr inbounds double, double addrspace(4)* getelementptr ([648 x double], [648 x double] addrspace(4)* addrspacecast ([648 x double] addrspace(3)* @lds to [648 x double] addrspace(4)*), i64 0, i64 384), i64 %idx0
   %asc = addrspacecast double addrspace(4)* %gep0 to double addrspace(3)*
@@ -18,10 +28,8 @@
 
 ; CHECK-LABEL: @constexpr_gep_gep_addrspacecast(
 ; CHECK: %gep0 = getelementptr inbounds double, double addrspace(3)* getelementptr inbounds ([648 x double], [648 x double] addrspace(3)* @lds, i64 0, i64 384), i64 %idx0
-; CHECK-NEXT: %1 = addrspacecast double addrspace(3)* %gep0 to double addrspace(4)*
-; CHECK-NEXT: %gep1 = getelementptr inbounds double, double addrspace(4)* %1, i64 %idx1
-; CHECK-NEXT: %asc = addrspacecast double addrspace(4)* %gep1 to double addrspace(3)*
-; CHECK-NEXT: store double 1.000000e+00, double addrspace(3)* %asc, align 8
+; CHECK-NEXT: %gep1 = getelementptr inbounds double, double addrspace(3)* %gep0, i64 %idx1
+; CHECK-NEXT: store double 1.000000e+00, double addrspace(3)* %gep1, align 8
 define void @constexpr_gep_gep_addrspacecast(i64 %idx0, i64 %idx1) {
   %gep0 = getelementptr inbounds double, double addrspace(4)* getelementptr ([648 x double], [648 x double] addrspace(4)* addrspacecast ([648 x double] addrspace(3)* @lds to [648 x double] addrspace(4)*), i64 0, i64 384), i64 %idx0
   %gep1 = getelementptr inbounds double, double addrspace(4)* %gep0, i64 %idx1