Index: include/llvm/IR/Instruction.h
===================================================================
--- include/llvm/IR/Instruction.h
+++ include/llvm/IR/Instruction.h
@@ -252,6 +252,9 @@
   /// Returns false if no metadata was found.
   bool extractProfTotalWeight(uint64_t &TotalVal) const;
 
+  /// Updates branch_weights metadata by scaling it by \p S / \p T.
+  void updateProfWeight(uint64_t S, uint64_t T);
+
   /// Set the debug location information for this instruction.
   void setDebugLoc(DebugLoc Loc) { DbgLoc = std::move(Loc); }
 
Index: lib/IR/Instruction.cpp
===================================================================
--- lib/IR/Instruction.cpp
+++ lib/IR/Instruction.cpp
@@ -17,6 +17,7 @@
 #include "llvm/IR/Constants.h"
 #include "llvm/IR/Instructions.h"
 #include "llvm/IR/Module.h"
+#include "llvm/IR/MDBuilder.h"
 #include "llvm/IR/Operator.h"
 #include "llvm/IR/Type.h"
 using namespace llvm;
@@ -674,3 +675,25 @@
   New->copyMetadata(*this);
   return New;
 }
+
+void Instruction::updateProfWeight(uint64_t S, uint64_t T) {
+  auto *ProfileData = getMetadata(LLVMContext::MD_prof);
+  if (!ProfileData.hasValue())
+    return;
+
+  auto *ProfDataName = dyn_cast<MDString>(ProfileData->getOperand(0));
+  if (!ProfDataName || !ProfDataName->getString().equals("branch_weights"))
+    return;
+
+  SmallVector<uint32_t, 4> Weights;
+  for (unsigned i = 1; i < ProfileData->getNumOperands(); i++) {
+    // Using APInt::div may be expensive, but most cases should fit in 64 bits.
+    APInt Val(128, mdconst::dyn_extract<ConstantInt>(ProfileData->getOperand(i))
+                       ->getValue()
+                       .getZExtValue());
+    Val *= APInt(128, S);
+    Weights.push_back(Val.udiv(APInt(128, T)).getLimitedValue());
+  }
+  MDBuilder MDB(getContext());
+  setMetadata(LLVMContext::MD_prof, MDB.createBranchWeights(Weights));
+}
Index: lib/Transforms/Utils/InlineFunction.cpp
===================================================================
--- lib/Transforms/Utils/InlineFunction.cpp
+++ lib/Transforms/Utils/InlineFunction.cpp
@@ -25,6 +25,7 @@
 #include "llvm/Analysis/CaptureTracking.h"
 #include "llvm/Analysis/EHPersonalities.h"
 #include "llvm/Analysis/InstructionSimplify.h"
+#include "llvm/Analysis/ProfileSummaryInfo.h"
 #include "llvm/Analysis/ValueTracking.h"
 #include "llvm/IR/Attributes.h"
 #include "llvm/IR/CallSite.h"
@@ -1425,28 +1426,55 @@
       ClonedBBs);
 }
 
+/// Update the branch metadata for cloned call instructions.
+static void updateCallProfile(Function *Callee, const ValueToValueMapTy &VMap,
+                              const Optional<uint64_t> &CalleeEntryCount,
+                              const Instruction *TheCall) {
+  if (!CalleeEntryCount.hasValue() || CalleeEntryCount.getValue() < 1)
+    return;
+  Optional<uint64_t> CallSiteCount =
+      ProfileSummaryInfo::getProfileCount(TheCall, nullptr);
+  uint64_t CallCount =
+      std::min(CallSiteCount.hasValue() ? CallSiteCount.getValue() : 0,
+               CalleeEntryCount.getValue());
+
+  for (auto const &Entry : VMap)
+    if (isa<CallInst>(Entry.first) && &*Entry.second != nullptr &&
+        isa<CallInst>(Entry.second))
+      cast<CallInst>(Entry.second)
+          ->updateProfWeight(CallCount, CalleeEntryCount.getValue());
+  for (BasicBlock &BB : *Callee)
+    // No need to update the callsite if it is pruned during inlining.
+    if (VMap.count(&BB))
+      for (Instruction &I : BB)
+        if (CallInst *CI = dyn_cast<CallInst>(&I))
+          CI->updateProfWeight(CalleeEntryCount.getValue() - CallCount,
+                               CalleeEntryCount.getValue());
+}
+
 /// Update the entry count of callee after inlining.
 ///
 /// The callsite's block count is subtracted from the callee's function entry
 /// count.
-static void updateCalleeCount(BlockFrequencyInfo &CallerBFI, BasicBlock *CallBB,
-                              Function *Callee) {
+static void updateCalleeCount(BlockFrequencyInfo *CallerBFI, BasicBlock *CallBB,
+                              Instruction *CallInst, Function *Callee) {
   // If the callee has a original count of N, and the estimated count of
   // callsite is M, the new callee count is set to N - M. M is estimated from
   // the caller's entry count, its entry block frequency and the block frequency
   // of the callsite.
   Optional<uint64_t> CalleeCount = Callee->getEntryCount();
-  if (!CalleeCount)
+  if (!CalleeCount.hasValue())
     return;
-  Optional<uint64_t> CallSiteCount = CallerBFI.getBlockProfileCount(CallBB);
-  if (!CallSiteCount)
+  Optional<uint64_t> CallCount =
+      ProfileSummaryInfo::getProfileCount(CallInst, CallerBFI);
+  if (!CallCount.hasValue())
     return;
   // Since CallSiteCount is an estimate, it could exceed the original callee
   // count and has to be set to 0.
-  if (CallSiteCount.getValue() > CalleeCount.getValue())
+  if (CallCount.getValue() > CalleeCount.getValue())
     Callee->setEntryCount(0);
   else
-    Callee->setEntryCount(CalleeCount.getValue() - CallSiteCount.getValue());
+    Callee->setEntryCount(CalleeCount.getValue() - CallCount.getValue());
 }
 
 /// This function inlines the called function into the basic block of the
@@ -1636,13 +1664,14 @@
     // Remember the first block that is newly cloned over.
     FirstNewBlock = LastBlock; ++FirstNewBlock;
 
-    if (IFI.CallerBFI != nullptr && IFI.CalleeBFI != nullptr) {
+    if (IFI.CallerBFI != nullptr && IFI.CalleeBFI != nullptr)
       // Update the BFI of blocks cloned into the caller.
       updateCallerBFI(OrigBB, VMap, IFI.CallerBFI, IFI.CalleeBFI,
                       CalledFunc->front());
-      // Update the profile count of callee.
-      updateCalleeCount(*IFI.CallerBFI, OrigBB, CalledFunc);
-    }
+
+    updateCallProfile(CalledFunc, VMap, CalledFunc->getEntryCount(), TheCall);
+    // Update the profile count of callee.
+    updateCalleeCount(IFI.CallerBFI, OrigBB, TheCall, CalledFunc);
 
     // Inject byval arguments initialization.
     for (std::pair<Value*, Value*> &Init : ByValInit)
Index: test/Transforms/Inline/prof-update.ll
===================================================================
--- /dev/null
+++ test/Transforms/Inline/prof-update.ll
@@ -0,0 +1,39 @@
+; RUN: opt < %s -inline -S | FileCheck %s
+; Checks if inliner updates branch_weights annotation for call instructions.
+
+declare void @ext();
+declare void @ext1();
+
+; CHECK: define void @callee(i32 %n) !prof ![[ENTRY_COUNT:[0-9]*]]
+define void  @callee(i32 %n) !prof !1 {
+  %cond = icmp sle i32 %n, 10
+  br i1 %cond, label %cond_true, label %cond_false
+cond_true:
+; ext1 is optimized away, thus not updated.
+; CHECK: call void @ext1(), !prof ![[COUNT_CALLEE1:[0-9]*]]
+  call void @ext1(), !prof !2
+  ret void
+cond_false:
+; ext is cloned and updated.
+; CHECK: call void @ext(), !prof ![[COUNT_CALLEE:[0-9]*]]
+  call void @ext(), !prof !2
+  ret void
+}
+
+; CHECK: define void @caller()
+define void @caller() {
+; CHECK: call void @ext(), !prof ![[COUNT_CALLER:[0-9]*]]
+  call void @callee(i32 15), !prof !3
+  ret void
+}
+
+!llvm.module.flags = !{!0}
+!0 = !{i32 1, !"MaxFunctionCount", i32 2000}
+!1 = !{!"function_entry_count", i64 1000}
+!2 = !{!"branch_weights", i64 2000}
+!3 = !{!"branch_weights", i64 400}
+attributes #0 = { alwaysinline }
+; CHECK: ![[ENTRY_COUNT]] = !{!"function_entry_count", i64 600}
+; CHECK: ![[COUNT_CALLEE1]] = !{!"branch_weights", i64 2000}
+; CHECK: ![[COUNT_CALLEE]] = !{!"branch_weights", i32 1200}
+; CHECK: ![[COUNT_CALLER]] = !{!"branch_weights", i32 800}