Index: lib/Transforms/Scalar/EarlyCSE.cpp
===================================================================
--- lib/Transforms/Scalar/EarlyCSE.cpp
+++ lib/Transforms/Scalar/EarlyCSE.cpp
@@ -766,7 +766,7 @@
     // memory.  The target may override this (e.g. so that a store intrinsic
     // does not read  from memory, and thus will be treated the same as a
     // regular store for commoning purposes).
-    if (Inst->mayReadFromMemory() &&
+    if ((Inst->mayReadFromMemory() || Inst->mayThrow()) &&
         !(MemInst.isValid() && !MemInst.mayReadFromMemory()))
       LastStore = nullptr;
 
Index: test/Transforms/EarlyCSE/readnone-mayunwind.ll
===================================================================
--- /dev/null
+++ test/Transforms/EarlyCSE/readnone-mayunwind.ll
@@ -0,0 +1,15 @@
+; RUN: opt -S -early-cse < %s | FileCheck %s
+
+declare void @readnone_may_unwind() readnone
+
+define void @f(i32* %ptr) {
+; CHECK-LABEL: @f(
+; CHECK: store i32 100, i32* %ptr
+; CHECK: call void @readnone_may_unwind()
+; CHECK: store i32 200, i32* %ptr
+
+  store i32 100, i32* %ptr
+  call void @readnone_may_unwind()
+  store i32 200, i32* %ptr
+  ret void
+}