Index: lib/asan/asan_report.cc
===================================================================
--- lib/asan/asan_report.cc
+++ lib/asan/asan_report.cc
@@ -471,7 +471,7 @@
   // previously. That's unfortunate, but I have no better solution,
   // especially given that the alloca may be from entirely different place
   // (e.g. use-after-scope, or different thread's stack).
-#if defined(__powerpc64__) && __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__
+#if SANITIZER_PPC64V1
   // On PowerPC64 ELFv1, the address of a function actually points to a
   // three-doubleword data structure with the first field containing
   // the address of the function's code.
Index: lib/msan/msan.h
===================================================================
--- lib/msan/msan.h
+++ lib/msan/msan.h
@@ -107,7 +107,7 @@
 # define MEM_TO_SHADOW(mem) ((uptr)mem ^ 0x6000000000ULL)
 # define SHADOW_TO_ORIGIN(shadow) (((uptr)(shadow)) + 0x1000000000ULL)
 
-#elif SANITIZER_LINUX && defined(__powerpc64__)
+#elif SANITIZER_LINUX && SANITIZER_PPC64
 
 const MappingDesc kMemoryLayout[] = {
     {0x000000000000ULL, 0x000100000000ULL, MappingDesc::APP, "low memory"},
Index: lib/sanitizer_common/sanitizer_platform.h
===================================================================
--- lib/sanitizer_common/sanitizer_platform.h
+++ lib/sanitizer_common/sanitizer_platform.h
@@ -123,6 +123,32 @@
 # define SANITIZER_S390_64 0
 #endif
 
+#if defined(__powerpc__)
+# define SANITIZER_PPC 1
+# if defined(__powerpc64__)
+#  define SANITIZER_PPC32 0
+#  define SANITIZER_PPC64 1
+#  if _CALL_ELF == 2
+#   define SANITIZER_PPC64V1 0
+#   define SANITIZER_PPC64V2 1
+#  else
+#   define SANITIZER_PPC64V1 1
+#   define SANITIZER_PPC64V2 0
+#  endif
+# else
+#  define SANITIZER_PPC32 1
+#  define SANITIZER_PPC64 0
+#  define SANITIZER_PPC64V1 0
+#  define SANITIZER_PPC64V2 0
+# endif
+#else
+# define SANITIZER_PPC 0
+# define SANITIZER_PPC32 0
+# define SANITIZER_PPC64 0
+# define SANITIZER_PPC64V1 0
+# define SANITIZER_PPC64V2 0
+#endif
+
 // By default we allow to use SizeClassAllocator64 on 64-bit platform.
 // But in some cases (e.g. AArch64's 39-bit address space) SizeClassAllocator64
 // does not work well and we need to fallback to SizeClassAllocator32.
Index: lib/tsan/rtl/tsan_interceptors.cc
===================================================================
--- lib/tsan/rtl/tsan_interceptors.cc
+++ lib/tsan/rtl/tsan_interceptors.cc
@@ -86,11 +86,9 @@
 };
 #endif
 
-#if defined(__x86_64__) || defined(__mips__) \
-  || (defined(__powerpc64__) && __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__)
+#if defined(__x86_64__) || defined(__mips__) || SANITIZER_PPC64V1
 #define PTHREAD_ABI_BASE  "GLIBC_2.3.2"
-#elif defined(__aarch64__) || (defined(__powerpc64__) \
-  && __BYTE_ORDER__ == __ORDER_LITTLE_ENDIAN__)
+#elif defined(__aarch64__) || SANITIZER_PPC64V2
 #define PTHREAD_ABI_BASE  "GLIBC_2.17"
 #endif