Index: include/lldb/Target/PathMappingList.h
===================================================================
--- include/lldb/Target/PathMappingList.h
+++ include/lldb/Target/PathMappingList.h
@@ -116,7 +116,9 @@
     bool
     RemapPath (const char *path, std::string &new_path) const;
 
-    
+    bool
+    ReverseRemapPath (const ConstString &path, ConstString &new_path) const;
+
     //------------------------------------------------------------------
     /// Finds a source file given a file spec using the path remappings.
     ///
Index: packages/Python/lldbsuite/test/source-manager/TestSourceManager.py
===================================================================
--- packages/Python/lldbsuite/test/source-manager/TestSourceManager.py
+++ packages/Python/lldbsuite/test/source-manager/TestSourceManager.py
@@ -170,3 +170,21 @@
         # Display the source code again.  We should see the updated line.
         self.expect("source list -f main.c -l %d" % self.line, SOURCE_DISPLAYED_CORRECTLY,
             substrs = ['Hello lldb'])
+
+    def test_set_breakpoint_with_absloute_path(self):
+        self.build()
+        self.runCmd("settings set target.source-map %s %s" % (os.getcwd(), os.path.join(os.getcwd(), "hidden")))
+
+        exe = os.path.join(os.getcwd(), "a.out")
+        main = os.path.join(os.getcwd(), "hidden", "main.c")
+        self.runCmd("file " + exe, CURRENT_EXECUTABLE_SET)
+
+        lldbutil.run_break_set_by_file_and_line (self, main, self.line, num_expected_locations=1, loc_exact=False)
+        
+        self.runCmd("run", RUN_SUCCEEDED)
+
+        # The stop reason of the thread should be breakpoint.
+        self.expect("thread list", STOPPED_DUE_TO_BREAKPOINT,
+            substrs = ['stopped',
+                       'main.c:%d' % self.line,
+                       'stop reason = breakpoint'])
Index: source/Target/PathMappingList.cpp
===================================================================
--- source/Target/PathMappingList.cpp
+++ source/Target/PathMappingList.cpp
@@ -215,6 +215,27 @@
 }
 
 bool
+PathMappingList::ReverseRemapPath (const ConstString &path, ConstString &new_path) const
+{
+    const char *path_cstr = path.GetCString();
+    if (!path_cstr)
+        return false;
+
+    for (const auto& it : m_pairs)
+    {
+        const size_t prefixLen = it.second.GetLength();
+        if (::strncmp (it.second.GetCString(), path_cstr, prefixLen) == 0)
+        {
+            std::string new_path_str (it.first.GetCString());
+            new_path_str.append(path.GetCString() + prefixLen);
+            new_path.SetCString(new_path_str.c_str());
+            return true;
+        }
+    }
+    return false;
+}
+
+bool
 PathMappingList::FindFile (const FileSpec &orig_spec, FileSpec &new_spec) const
 {
     if (!m_pairs.empty())
Index: source/Target/Target.cpp
===================================================================
--- source/Target/Target.cpp
+++ source/Target/Target.cpp
@@ -348,6 +348,13 @@
                           bool hardware,
                           LazyBool move_to_nearest_code)
 {
+    FileSpec remapped_file;
+    ConstString remapped_path;
+    if (GetSourcePathMap().ReverseRemapPath(ConstString(file.GetPath().c_str()), remapped_path))
+        remapped_file.SetFile(remapped_path.AsCString(), true);
+    else
+        remapped_file = file;
+
     if (check_inlines == eLazyBoolCalculate)
     {
         const InlineStrategy inline_strategy = GetInlineStrategy();
@@ -358,7 +365,7 @@
                 break;
                 
             case eInlineBreakpointsHeaders:
-                if (file.IsSourceImplementationFile())
+                if (remapped_file.IsSourceImplementationFile())
                     check_inlines = eLazyBoolNo;
                 else
                     check_inlines = eLazyBoolYes;
@@ -374,7 +381,7 @@
     {
         // Not checking for inlines, we are looking only for matching compile units
         FileSpecList compile_unit_list;
-        compile_unit_list.Append (file);
+        compile_unit_list.Append (remapped_file);
         filter_sp = GetSearchFilterForModuleAndCUList (containingModules, &compile_unit_list);
     }
     else
@@ -387,7 +394,7 @@
         move_to_nearest_code = GetMoveToNearestCode() ? eLazyBoolYes : eLazyBoolNo;
 
     BreakpointResolverSP resolver_sp(new BreakpointResolverFileLine(nullptr,
-                                                                    file,
+                                                                    remapped_file,
                                                                     line_no,
                                                                     check_inlines,
                                                                     skip_prologue,