Index: lldb/include/lldb/Core/Disassembler.h
===================================================================
--- lldb/include/lldb/Core/Disassembler.h
+++ lldb/include/lldb/Core/Disassembler.h
@@ -473,6 +473,8 @@
   virtual bool FlavorValidForArchSpec(const lldb_private::ArchSpec &arch,
                                       const char *flavor) = 0;
 
+  virtual void SetUseColor(bool use_color) {}
+
 protected:
   // SourceLine and SourceLinesToDisplay structures are only used in the mixed
   // source and assembly display methods internal to this class.
Index: lldb/source/Core/Disassembler.cpp
===================================================================
--- lldb/source/Core/Disassembler.cpp
+++ lldb/source/Core/Disassembler.cpp
@@ -291,6 +291,8 @@
   SourceManager &source_manager =
       target_sp ? target_sp->GetSourceManager() : debugger.GetSourceManager();
 
+  SetUseColor(debugger.GetUseColor());
+
   if (frame) {
     pc_addr_ptr = &frame->GetFrameCodeAddress();
   }
Index: lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.h
===================================================================
--- lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.h
+++ lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.h
@@ -42,6 +42,8 @@
                             lldb::offset_t data_offset, size_t num_instructions,
                             bool append, bool data_from_file) override;
 
+  void SetUseColor(bool use_color) override;
+
   // PluginInterface protocol
   llvm::StringRef GetPluginName() override { return GetPluginNameStatic(); }
 
Index: lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.cpp
===================================================================
--- lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.cpp
+++ lldb/source/Plugins/Disassembler/LLVMC/DisassemblerLLVMC.cpp
@@ -9,6 +9,7 @@
 #include "DisassemblerLLVMC.h"
 
 #include "llvm-c/Disassembler.h"
+#include "llvm/ADT/ScopeExit.h"
 #include "llvm/ADT/SmallString.h"
 #include "llvm/ADT/StringExtras.h"
 #include "llvm/MC/MCAsmInfo.h"
@@ -63,6 +64,8 @@
   void PrintMCInst(llvm::MCInst &mc_inst, lldb::addr_t pc,
                    std::string &inst_string, std::string &comments_string);
   void SetStyle(bool use_hex_immed, HexImmediateStyle hex_style);
+  void SetUseColor(bool use_color);
+  bool GetUseColor() const;
   bool CanBranch(llvm::MCInst &mc_inst) const;
   bool HasDelaySlot(llvm::MCInst &mc_inst) const;
   bool IsCall(llvm::MCInst &mc_inst) const;
@@ -576,6 +579,12 @@
         else
           mc_disasm_ptr = disasm->m_disasm_up.get();
 
+        // Disable coloring for the duration of this function.
+        const bool saved_use_color = mc_disasm_ptr->GetUseColor();
+        mc_disasm_ptr->SetUseColor(false);
+        auto on_exit = llvm::make_scope_exit(
+            [=]() { mc_disasm_ptr->SetUseColor(saved_use_color); });
+
         lldb::addr_t pc = m_address.GetFileAddress();
         m_using_file_addr = true;
 
@@ -1344,10 +1353,12 @@
   llvm::raw_string_ostream inst_stream(inst_string);
   llvm::raw_string_ostream comments_stream(comments_string);
 
+  inst_stream.enable_colors(m_instr_printer_up->getUseColor());
   m_instr_printer_up->setCommentStream(comments_stream);
   m_instr_printer_up->printInst(&mc_inst, pc, llvm::StringRef(),
                                 *m_subtarget_info_up, inst_stream);
   m_instr_printer_up->setCommentStream(llvm::nulls());
+
   comments_stream.flush();
 
   static std::string g_newlines("\r\n");
@@ -1374,6 +1385,14 @@
   }
 }
 
+void DisassemblerLLVMC::MCDisasmInstance::SetUseColor(bool use_color) {
+  m_instr_printer_up->setUseColor(use_color);
+}
+
+bool DisassemblerLLVMC::MCDisasmInstance::GetUseColor() const {
+  return m_instr_printer_up->getUseColor();
+}
+
 bool DisassemblerLLVMC::MCDisasmInstance::CanBranch(
     llvm::MCInst &mc_inst) const {
   if (m_instr_analysis_up)
@@ -1597,6 +1616,13 @@
   return lldb::DisassemblerSP();
 }
 
+void DisassemblerLLVMC::SetUseColor(bool use_color) {
+  if (m_disasm_up)
+    m_disasm_up->SetUseColor(use_color);
+  if (m_alternate_disasm_up)
+    m_alternate_disasm_up->SetUseColor(use_color);
+}
+
 size_t DisassemblerLLVMC::DecodeInstructions(const Address &base_addr,
                                              const DataExtractor &data,
                                              lldb::offset_t data_offset,
Index: lldb/test/API/python_api/disassemble-raw-data/TestDisassembleRawData.py
===================================================================
--- lldb/test/API/python_api/disassemble-raw-data/TestDisassembleRawData.py
+++ lldb/test/API/python_api/disassemble-raw-data/TestDisassembleRawData.py
@@ -59,9 +59,19 @@
         elif arch in ("aarch64", "arm64"):
             self.assertEqual(inst.GetMnemonic(target), "mov")
             self.assertEqual(inst.GetOperands(target), "w0, #0x63")
+            self.assertEqual(inst.GetComment(target), "=99 ")
             self.assertEqual(
                 inst.GetControlFlowKind(target), lldb.eInstructionControlFlowKindUnknown
             )
+            # Make sure that using colors doesn't affect the output here.
+            res = lldb.SBCommandReturnObject()
+            ci = self.dbg.GetCommandInterpreter()
+            ci.HandleCommand("settings set use-color true", res)
+            self.assertEqual(inst.GetOperands(target), "w0, #0x63")
+            self.assertEqual(inst.GetMnemonic(target), "mov")
+            self.assertEqual(inst.GetComment(target), "=99 ")
+            ci.HandleCommand("settings set use-color false", res)
+
         elif arch == "arm":
             self.assertEqual(inst.GetMnemonic(target), "mov")
             self.assertEqual(inst.GetOperands(target), "r3, #99")