Index: llvm/lib/Analysis/ProfileSummaryInfo.cpp
===================================================================
--- llvm/lib/Analysis/ProfileSummaryInfo.cpp
+++ llvm/lib/Analysis/ProfileSummaryInfo.cpp
@@ -90,6 +90,11 @@
       return TotalCount;
     return std::nullopt;
   }
+  if (auto *Called = Call.getCalledFunction()) {
+    auto CalledCount = Called->getEntryCount();
+    if (CalledCount && !CalledCount->getCount())
+      return 0;
+  }
   if (BFI)
     return BFI->getBlockProfileCount(Call.getParent(), AllowSynthetic);
   return std::nullopt;
Index: llvm/test/Transforms/Inline/inline-zero-count-call.ll
===================================================================
--- /dev/null
+++ llvm/test/Transforms/Inline/inline-zero-count-call.ll
@@ -0,0 +1,62 @@
+; RUN: opt < %s -passes='require<profile-summary>,cgscc(inline)' -S | FileCheck %s
+
+; This tests a call to a function with zero entry count while no profile data
+; is available for the basic block of the call site.
+
+define void  @noprofile_f(i32 %n) "function-inline-cost"="15" {
+; CHECK-LABEL: define void @noprofile_f
+; CHECK:       cond_false:
+; CHECK-NEXT:    call void @zero_count_f()
+; CHECK-NEXT:    ret void
+;
+  %cond = icmp sle i32 %n, 10
+  br i1 %cond, label %cond_true, label %cond_false
+cond_true:
+  call void @extern_f()
+  ret void
+cond_false:
+  call void @zero_count_f()
+  ret void
+}
+
+define void @pprofile_f(i32 %n) !prof !16 {
+; CHECK-LABEL: define void @pprofile_f
+; CHECK:       cond_false:
+; CHECK-NEXT:    call void @zero_count_f()
+; CHECK-NEXT:    ret void
+;
+  %cond = icmp sle i32 %n, 10
+  br i1 %cond, label %cond_true, label %cond_false
+cond_true:
+  call void @extern_f()
+  ret void
+cond_false:
+  call void @zero_count_f()
+  ret void
+}
+
+define void @zero_count_f() #0  "function-inline-cost"="75" !prof !15 {
+  ret void
+}
+
+declare void @extern_f()
+attributes #0 = { cold }
+
+!15 = !{!"function_entry_count", i64 0}
+!16 = !{!"function_entry_count", i64 1000000}
+
+!llvm.module.flags = !{!1}
+!1 = !{i32 1, !"ProfileSummary", !2}
+!2 = !{!3, !4, !5, !6, !7, !8, !9, !10}
+!3 = !{!"ProfileFormat", !"InstrProf"}
+!4 = !{!"TotalCount", i64 1000000}
+!5 = !{!"MaxCount", i64 1000000}
+!6 = !{!"MaxInternalCount", i64 1}
+!7 = !{!"MaxFunctionCount", i64 1000000}
+!8 = !{!"NumCounts", i64 100}
+!9 = !{!"NumFunctions", i64 100}
+!10 = !{!"DetailedSummary", !11}
+!11 = !{!12, !13, !14}
+!12 = !{i32 10000, i64 100, i32 1}
+!13 = !{i32 990000, i64 100, i32 1}
+!14 = !{i32 999999, i64 1, i32 2}