diff --git a/llvm/lib/Target/AArch64/AArch64ISelLowering.cpp b/llvm/lib/Target/AArch64/AArch64ISelLowering.cpp
--- a/llvm/lib/Target/AArch64/AArch64ISelLowering.cpp
+++ b/llvm/lib/Target/AArch64/AArch64ISelLowering.cpp
@@ -13894,7 +13894,17 @@
   case Intrinsic::aarch64_neon_ld4:
   case Intrinsic::aarch64_neon_ld1x2:
   case Intrinsic::aarch64_neon_ld1x3:
-  case Intrinsic::aarch64_neon_ld1x4:
+  case Intrinsic::aarch64_neon_ld1x4: {
+    Info.opc = ISD::INTRINSIC_W_CHAIN;
+    uint64_t NumElts = DL.getTypeSizeInBits(I.getType()) / 64;
+    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), MVT::i64, NumElts);
+    Info.ptrVal = I.getArgOperand(I.arg_size() - 1);
+    Info.offset = 0;
+    Info.align.reset();
+    // volatile loads with NEON intrinsics not supported
+    Info.flags = MachineMemOperand::MOLoad;
+    return true;
+  }
   case Intrinsic::aarch64_neon_ld2lane:
   case Intrinsic::aarch64_neon_ld3lane:
   case Intrinsic::aarch64_neon_ld4lane:
@@ -13902,9 +13912,13 @@
   case Intrinsic::aarch64_neon_ld3r:
   case Intrinsic::aarch64_neon_ld4r: {
     Info.opc = ISD::INTRINSIC_W_CHAIN;
-    // Conservatively set memVT to the entire set of vectors loaded.
-    uint64_t NumElts = DL.getTypeSizeInBits(I.getType()) / 64;
-    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), MVT::i64, NumElts);
+    // ldx return struct with the same vec type
+    Type *RetTy = I.getType();
+    auto *StructTy = cast<StructType>(RetTy);
+    unsigned NumElts = StructTy->getNumElements();
+    Type *VecTy = StructTy->getElementType(0);
+    MVT EleVT = MVT::getVT(VecTy).getVectorElementType();
+    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), EleVT, NumElts);
     Info.ptrVal = I.getArgOperand(I.arg_size() - 1);
     Info.offset = 0;
     Info.align.reset();
@@ -13917,20 +13931,40 @@
   case Intrinsic::aarch64_neon_st4:
   case Intrinsic::aarch64_neon_st1x2:
   case Intrinsic::aarch64_neon_st1x3:
-  case Intrinsic::aarch64_neon_st1x4:
+  case Intrinsic::aarch64_neon_st1x4: {
+    Info.opc = ISD::INTRINSIC_VOID;
+    unsigned NumElts = 0;
+    for (const Value *Arg : I.args()) {
+      Type *ArgTy = Arg->getType();
+      if (!ArgTy->isVectorTy())
+        break;
+      NumElts += DL.getTypeSizeInBits(ArgTy) / 64;
+    }
+    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), MVT::i64, NumElts);
+    Info.ptrVal = I.getArgOperand(I.arg_size() - 1);
+    Info.offset = 0;
+    Info.align.reset();
+    // volatile stores with NEON intrinsics not supported
+    Info.flags = MachineMemOperand::MOStore;
+    return true;
+  }
   case Intrinsic::aarch64_neon_st2lane:
   case Intrinsic::aarch64_neon_st3lane:
   case Intrinsic::aarch64_neon_st4lane: {
     Info.opc = ISD::INTRINSIC_VOID;
-    // Conservatively set memVT to the entire set of vectors stored.
     unsigned NumElts = 0;
+    // all the vector type is same
+    Type *VecTy = I.getArgOperand(0)->getType();
+    MVT EleVT = MVT::getVT(VecTy).getVectorElementType();
+
     for (const Value *Arg : I.args()) {
       Type *ArgTy = Arg->getType();
       if (!ArgTy->isVectorTy())
         break;
-      NumElts += DL.getTypeSizeInBits(ArgTy) / 64;
+      NumElts += 1;
     }
-    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), MVT::i64, NumElts);
+
+    Info.memVT = EVT::getVectorVT(I.getType()->getContext(), EleVT, NumElts);
     Info.ptrVal = I.getArgOperand(I.arg_size() - 1);
     Info.offset = 0;
     Info.align.reset();
diff --git a/llvm/test/CodeGen/AArch64/arm64-neon-st-lane-aa.ll b/llvm/test/CodeGen/AArch64/arm64-neon-st-lane-aa.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/AArch64/arm64-neon-st-lane-aa.ll
@@ -0,0 +1,34 @@
+; RUN: llc < %s -mtriple=arm64-none-linux-gnu -mattr=+neon -O2 | FileCheck %s 
+
+; st2 must before two ldrb.
+; The situation that put one ldrb before st2 because of the conservative memVT set for st2lane,
+; which lead to basic-aa goes wrong.
+ 
+define dso_local i32 @test_vst2_lane_u8([2 x <8 x i8>] %vectors.coerce) local_unnamed_addr {
+; CHECK-LABEL:   test_vst2_lane_u8:
+; CHECK:         st2 { v[[V1:[0-9]+]].b, v[[V2:[0-9]+]].b }[6], [x8]
+; CHECK-NEXT:    umov w[[W1:[0-9]+]], v[[V12:[0-9]+]].b[6]
+; CHECK-NEXT:    ldrb w[[W2:[0-9]+]], [sp, #12]
+; CHECK-NEXT:    ldrb w[[W2:[0-9]+]], [sp, #13]
+entry:
+  %temp = alloca [2 x i8], align 4
+  %vectors.coerce.fca.0.extract = extractvalue [2 x <8 x i8>] %vectors.coerce, 0
+  %vectors.coerce.fca.1.extract = extractvalue [2 x <8 x i8>] %vectors.coerce, 1
+  call void @llvm.lifetime.start.p0(i64 2, ptr nonnull %temp) #4
+  call void @llvm.aarch64.neon.st2lane.v8i8.p0(<8 x i8> %vectors.coerce.fca.0.extract, <8 x i8> %vectors.coerce.fca.1.extract, i64 6, ptr nonnull %temp)
+  %0 = load i8, ptr %temp, align 4
+  %vget_lane = extractelement <8 x i8> %vectors.coerce.fca.0.extract, i64 6
+  %cmp8.not = icmp ne i8 %0, %vget_lane
+  %arrayidx3.1 = getelementptr inbounds [2 x i8], ptr %temp, i64 0, i64 1
+  %1 = load i8, ptr %arrayidx3.1, align 1
+  %vget_lane.1 = extractelement <8 x i8> %vectors.coerce.fca.1.extract, i64 6
+  %cmp8.not.1 = icmp ne i8 %1, %vget_lane.1
+  %or.cond = select i1 %cmp8.not, i1 true, i1 %cmp8.not.1
+  %cmp.lcssa = zext i1 %or.cond to i32
+  call void @llvm.lifetime.end.p0(i64 2, ptr nonnull %temp) #4
+  ret i32 %cmp.lcssa
+}
+ 
+declare void @llvm.lifetime.start.p0(i64 immarg, ptr nocapture) #2
+declare void @llvm.aarch64.neon.st2lane.v8i8.p0(<8 x i8>, <8 x i8>, i64, ptr nocapture) #2
+declare void @llvm.lifetime.end.p0(i64 immarg, ptr nocapture) #2
diff --git a/llvm/test/CodeGen/AArch64/multi-vector-load-size.ll b/llvm/test/CodeGen/AArch64/multi-vector-load-size.ll
new file mode 100644
--- /dev/null
+++ b/llvm/test/CodeGen/AArch64/multi-vector-load-size.ll
@@ -0,0 +1,106 @@
+; RUN: llc -mtriple=aarch64-linux-gnu -stop-after=instruction-select < %s | FileCheck %s
+
+%struct.__neon_float32x2x2_t = type { <2 x float>,  <2 x float> }
+%struct.__neon_float32x2x3_t = type { <2 x float>,  <2 x float>,  <2 x float> }
+%struct.__neon_float32x2x4_t = type { <2 x float>,  <2 x float>, <2 x float>,  <2 x float> }
+
+declare %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4.v2f32.p0f32(float*)
+
+declare %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld1x2.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld1x3.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld1x4.v2f32.p0f32(float*)
+
+declare %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2r.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3r.v2f32.p0f32(float*)
+declare %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4r.v2f32.p0f32(float*)
+
+declare %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2lane.v2f32.p0f32(<2 x float>, <2 x float>, i64, float*)
+declare %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3lane.v2f32.p0f32(<2 x float>, <2 x float>, <2 x float>, i64, float*)
+declare %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4lane.v2f32.p0f32(<2 x float>, <2 x float>, <2 x float>, <2 x float>, i64, float*)
+
+
+define %struct.__neon_float32x2x2_t @test_ld2(float* %addr) {
+  ; CHECK-LABEL: name: test_ld2
+  ; CHECK: LD2Twov2s {{.*}} :: (load (s128) {{.*}})
+  %val = call %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x2_t %val
+}
+
+define %struct.__neon_float32x2x3_t @test_ld3(float* %addr) {
+  ; CHECK-LABEL: name: test_ld3
+  ; CHECK: LD3Threev2s {{.*}} :: (load (s192) {{.*}})
+  %val = call %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x3_t %val
+}
+
+define %struct.__neon_float32x2x4_t @test_ld4(float* %addr) {
+  ; CHECK-LABEL: name: test_ld4
+  ; CHECK: LD4Fourv2s {{.*}} :: (load (s256) {{.*}})
+  %val = call %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x4_t %val
+}
+
+define %struct.__neon_float32x2x2_t @test_ld1x2(float* %addr) {
+  ; CHECK-LABEL: name: test_ld1x2
+  ; CHECK: LD1Twov2s {{.*}} :: (load (s128) {{.*}})
+  %val = call %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld1x2.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x2_t %val
+}
+
+define %struct.__neon_float32x2x3_t @test_ld1x3(float* %addr) {
+  ; CHECK-LABEL: name: test_ld1x3
+  ; CHECK: LD1Threev2s {{.*}} :: (load (s192) {{.*}})
+  %val = call %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld1x3.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x3_t %val
+}
+
+define %struct.__neon_float32x2x4_t @test_ld1x4(float* %addr) {
+  ; CHECK-LABEL: name: test_ld1x4
+  ; CHECK: LD1Fourv2s {{.*}} :: (load (s256) {{.*}})
+  %val = call %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld1x4.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x4_t %val
+}
+
+define %struct.__neon_float32x2x2_t @test_ld2r(float* %addr) {
+  ; CHECK-LABEL: name: test_ld2r
+  ; CHECK: LD2Rv2s {{.*}} :: (load (s64) {{.*}})
+  %val = call %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2r.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x2_t %val
+}
+
+define %struct.__neon_float32x2x3_t @test_ld3r(float* %addr) {
+  ; CHECK-LABEL: name: test_ld3r
+  ; CHECK: LD3Rv2s {{.*}} :: (load (s96) {{.*}})
+  %val = call %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3r.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x3_t %val
+}
+
+define %struct.__neon_float32x2x4_t @test_ld4r(float* %addr) {
+  ; CHECK-LABEL: name: test_ld4r
+  ; CHECK: LD4Rv2s {{.*}} :: (load (s128) {{.*}})
+  %val = call %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4r.v2f32.p0f32(float* %addr)
+  ret %struct.__neon_float32x2x4_t %val
+}
+
+define %struct.__neon_float32x2x2_t @test_ld2lane(<2 x float> %a, <2 x float> %b, float* %addr) {
+  ; CHECK-LABEL: name: test_ld2lane
+  ; CHECK: {{.*}} LD2i32 {{.*}}
+  %val = call %struct.__neon_float32x2x2_t @llvm.aarch64.neon.ld2lane.v2f32.p0f32(<2 x float> %a, <2 x float> %b, i64 1, float* %addr)
+  ret %struct.__neon_float32x2x2_t %val
+}
+
+define %struct.__neon_float32x2x3_t @test_ld3lane(<2 x float> %a, <2 x float> %b, <2 x float> %c, float* %addr) {
+  ; CHECK-LABEL: name: test_ld3lane
+  ; CHECK: {{.*}} LD3i32 {{.*}}
+  %val = call %struct.__neon_float32x2x3_t @llvm.aarch64.neon.ld3lane.v2f32.p0f32(<2 x float> %a, <2 x float> %b, <2 x float> %c, i64 1, float* %addr)
+  ret %struct.__neon_float32x2x3_t %val
+}
+
+define %struct.__neon_float32x2x4_t @test_ld4lane(<2 x float> %a, <2 x float> %b, <2 x float> %c, <2 x float> %d, float* %addr) {
+  ; CHECK-LABEL: name: test_ld4lane
+  ; CHECK: {{.*}} LD4i32 {{.*}}
+  %val = call %struct.__neon_float32x2x4_t @llvm.aarch64.neon.ld4lane.v2f32.p0f32(<2 x float> %a, <2 x float> %b, <2 x float> %c, <2 x float> %d, i64 1, float* %addr)
+  ret %struct.__neon_float32x2x4_t %val
+}
\ No newline at end of file
diff --git a/llvm/test/CodeGen/AArch64/multi-vector-store-size.ll b/llvm/test/CodeGen/AArch64/multi-vector-store-size.ll
--- a/llvm/test/CodeGen/AArch64/multi-vector-store-size.ll
+++ b/llvm/test/CodeGen/AArch64/multi-vector-store-size.ll
@@ -23,8 +23,6 @@
   %cr = fadd <4 x float> %cl, %dl
   %dr = fadd <4 x float> %dl, %al
 
-; The sizes below are conservative.  AArch64TargetLowering
-; conservatively assumes the entire vector is stored.
   tail call void @llvm.aarch64.neon.st2.v4f32.p0(<4 x float> %ar, <4 x float> %br, ptr %res)
 ; CHECK: ST2Twov4s {{.*}} :: (store (s256) {{.*}})
   tail call void @llvm.aarch64.neon.st3.v4f32.p0(<4 x float> %ar, <4 x float> %br, <4 x float> %cr, ptr %res)
@@ -46,8 +44,6 @@
   %cr = fadd <4 x float> %cl, %dl
   %dr = fadd <4 x float> %dl, %al
 
-; The sizes below are conservative.  AArch64TargetLowering
-; conservatively assumes the entire vector is stored.
   tail call void @llvm.aarch64.neon.st1x2.v4f32.p0(<4 x float> %ar, <4 x float> %br, ptr %res)
 ; CHECK: ST1Twov4s {{.*}} :: (store (s256) {{.*}})
   tail call void @llvm.aarch64.neon.st1x3.v4f32.p0(<4 x float> %ar, <4 x float> %br, <4 x float> %cr, ptr %res)
@@ -69,14 +65,12 @@
   %cr = fadd <4 x float> %cl, %dl
   %dr = fadd <4 x float> %dl, %al
 
-; The sizes below are conservative.  AArch64TargetLowering
-; conservatively assumes the entire vector is stored.
   tail call void @llvm.aarch64.neon.st2lane.v4f32.p0(<4 x float> %ar, <4 x float> %br, i64 1, ptr %res)
-; CHECK: ST2i32 {{.*}} :: (store (s256) {{.*}})
+; CHECK: ST2i32 {{.*}} :: (store (s64) {{.*}})
   tail call void @llvm.aarch64.neon.st3lane.v4f32.p0(<4 x float> %ar, <4 x float> %br, <4 x float> %cr, i64 1, ptr %res)
-; CHECK: ST3i32 {{.*}} :: (store (s384) {{.*}})
+; CHECK: ST3i32 {{.*}} :: (store (s96) {{.*}})
   tail call void @llvm.aarch64.neon.st4lane.v4f32.p0(<4 x float> %ar, <4 x float> %br, <4 x float> %cr, <4 x float> %dr, i64 1, ptr %res)
-; CHECK: ST4i32 {{.*}} :: (store (s512) {{.*}})
+; CHECK: ST4i32 {{.*}} :: (store (s128) {{.*}})
 
   ret void
 }